Results 1 to 10 of about 5,300,714 (382)

Memory Disorders Related to Hippocampal Function: The Interest of 5-HT₄Rs Targeting. [PDF]

Int J Mol Sci, 2021
The hippocampus has long been considered as a key structure for memory processes. Multilevel alterations of hippocampal function have been identified as a common denominator of memory impairments in a number of psychiatric and neurodegenerative diseases.
Roux CM, Leger M, Freret T.
europepmc   +2 more sources

Experiences of people with memory disorders and their spouse carers on influencing formal care: "They ask my wife questions that they should ask me". [PDF]

Dementia (London), 2021
Background People with memory disorders often need care and help from family carers and health and social care providers. Due to the deterioration of cognitive capacity and language skills, they may be unable to convey their thoughts and care preferences
Aaltonen MS, Martin-Matthews A, Pulkki JM, Eskola P, Jolanki OH.   +4 more
europepmc   +2 more sources

Disorders of memory [PDF]

Brain, 2002
This paper reviews disorders of memory. After a brief survey of the clinical varieties of the amnesic syndrome, transient and persistent, selected theoretical issues will be considered by posing a series of questions. (i) What is impaired and what is spared in anterograde amnesia?
Michael D. Kopelman
openalex   +4 more sources

An Interactional Profile to Assist the Differential Diagnosis of Neurodegenerative and Functional Memory Disorders. [PDF]

Alzheimer Dis Assoc Disord, 2018
Objective: Specialist services for dementia are seeing an increasing number of patients. We investigated whether interactional and linguistic features in the communication behavior of patients with memory problems could help distinguish between those ...
Reuber M, Blackburn DJ, Elsey C, Wakefield S, Ardern KA, Harkness K, Venneri A, Jones D, Shaw C, Drew P.   +9 more
europepmc   +2 more sources

Memory disorders in children [PDF]

, 2013
Memory disorders are a frequent consequence of a variety of childhood neurological conditions. We will review the characteristics of memory disorders as a function of the main four memory systems: short-term memory, episodic memory, semantic memory, and ...
Baddeley, Baddeley, Baddeley, Cornoldi, Hanten, Hermann, Majerus, Majerus, Majerus, Majerus, Scott, Temple, Temple, Ullman   +13 more
core   +4 more sources

Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer’s disease-like pathology

Nature Communications, 2021
Most instances of Alzheimer’s disease (AD) are sporadic or not associated with a particular mutation. Here, the authors develop knock-in mice that express wildtype human Aβ under control of the mouse App locus, which may have potential for modelling some
David Baglietto-Vargas, Stefania Forner, Lena Cai, Alessandra C. Martini, Laura Trujillo-Estrada, Vivek Swarup, Marie Minh Thu Nguyen, Kelly Do Huynh, Dominic I. Javonillo, Kristine Minh Tran, Jimmy Phan, Shan Jiang, Enikö A. Kramár, Cristina Nuñez-Diaz, Gabriela Balderrama-Gutierrez, Franklin Garcia, Jessica Childs, Carlos J. Rodriguez-Ortiz, Juan Antonio Garcia-Leon, Masashi Kitazawa, Mohammad Shahnawaz, Dina P. Matheos, Xinyi Ma, Celia Da Cunha, Ken C. Walls, Rahasson R. Ager, Claudio Soto, Antonia Gutierrez, Ines Moreno-Gonzalez, Ali Mortazavi, Andrea J. Tenner, Grant R. MacGregor, Marcelo Wood, Kim N. Green, Frank M. LaFerla   +34 more
doaj   +1 more source

Grey and white matter correlates of recent and remote autobiographical memory retrieval:Insights from the dementias [PDF]

, 2014
The capacity to remember self-referential past events relies on the integrity of a distributed neural network. Controversy exists, however, regarding the involvement of specific brain structures for the retrieval of recently experienced versus more ...
A Barnabe, A Gilboa, A Gilboa, A Mechelli, A Viard, A Viard, AE Cavanna, B Levine, Bonnie Y. K. Lam, BYK Lam, CM Kipps, D Rueckert, DL Greenberg, DL Greenberg, DR Addis, E Mioshi, E Mioshi, E Svoboda, EA Maguire, EA Maguire, EA Maguire, G Northoff, G Winocur, GB Karas, GM McKhann, H Söderlund, HE Moss, HJ Rosen, HJ Rosen, HM Bonnici, J Ashburner, J Greene, J Morris, John R. Hodges, JR Binder, JR Hodges, K Oishi, K Rascovsky, L Nadel, L Squire, Laurie Miller, M Irish, M Irish, M Irish, M Irish, M Irish, M Irish, M Irish, M McKinnon, M Mion, M Moscovitch, M Piefke, M Sollberger, M Sugiura, M Visser, MA Conway, MA Conway, Michael Hornberger, ML Gorno-Tempini, Muireann Irish, N Philippi, O Meulenbroek, Olivier Piguet, P Piolino, P Piolino, P Piolino, P Piolino, R Cabeza, R Reitan, R Westmacott, Ramon Trullas, RS Rosenbaum, S Mori, S Oddo, S Savage, S Sheldon, S Steinvorth, Shadi El Wahsh, Sharpley Hsieh, SM Smith, SM Smith, SM Smith, Suncica Lah, TC Chua, TE Nichols, V Matuszewski, Y Zhang   +86 more
core   +6 more sources

Reasons for undergoing amyloid imaging among cognitively unimpaired older adults

Annals of Clinical and Translational Neurology, 2021
Objectives Preclinical Alzheimer’s disease (AD) clinical trials screen cognitively unimpaired older adults for biomarker criteria and disclose their results.
Mary M. Ryan, Daniel L. Gillen, Joshua D. Grill   +2 more
doaj   +1 more source

Abuse in the caregiving relationship between older people with memory disorders and family caregivers: A systematic review.

Journal of Advanced Nursing, 2020
AIM To synthesize what is known about elder abuse and relationship factors associated with abuse between caregivers and older people with memory disorders at home. BACKGROUND Concerns about abuse within the caring relationship between older people with
T. Välimäki, A. Mäki-Petäjä-Leinonen, M. Vaismoradi   +2 more
semanticscholar   +1 more source

Estimating attrition in mild-to-moderate Alzheimer’s disease and mild cognitive impairment clinical trials

Alzheimer’s Research & Therapy, 2023
Background Participant retention is a key factor that affects clinical trial integrity. Trial protocols estimate attrition as a function of sample size calculations. Alzheimer’s disease (AD) is an area of active treatment development.
Marina Ritchie, Daniel L. Gillen, Joshua D. Grill   +2 more
doaj   +1 more source