Quantitative, High-Throughput Assays for Proteolytic Degradation of Amylin
Methods and Protocols, 2020 Amylin is a pancreatic peptide hormone that regulates glucose homeostasis but also aggregates to form islet amyloid in type-2 diabetes. Given its role in both health and disease, there is renewed interest in proteolytic degradation of amylin by insulin ...
Caitlin N. Suire +2 more
doaj +1 more source
Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease
Scientific Data, 2021 Measurement(s) Protein Expression • gene expression • electrophysiology data • protein measurement • behavior Technology Type(s) immunofluorescence microscopy assay • RNA sequencing • electrophysiology assay • Electrochemiluminescence Immunoassay ...
Stefania Forner +20 more
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Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2020 Introduction We sought to examine the association of race/ethnicity with willingness to engage in studies that involve procedures typical of Alzheimer's disease (AD) clinical trials and determine whether any observed differences could be explained by ...
Christian R. Salazar +3 more
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Mapping dynamic interactions among cognitive biases in depression [PDF]
, 2020 Depression is theorized to be caused in part by biased cognitive processing of emotional information. Yet, prior research has adopted a reductionist approach that does not characterize how biases in cognitive processes such as attention and memory work ...
Bernstein, Amit +3 more
core +1 more source
Potential health effects of Champagne wine consumption [PDF]
, 2011 Epidemiological studies have suggested an inverse correlation between red wine consumption and the incidence of cardiovascular and neurodegenerative disorders.
Corona, Giulia +7 more
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A physiological marker of recognition memory in adults with autism spectrum disorder? The Pupil Old/New Effect [PDF]
, 2020 This study investigated the pupil Old/New effect in individuals with Autism Spectrum Disorder (ASD) and typical development (TD). Participants studied verbal and visual meaningful and meaningless materials in black and white on a computer screen.
Bowler, D. M., Gaigg, S. B., Ring, M.
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Overgeneral past and future thinking in dysphoria: the role of emotional cues and cueing methodology [PDF]
, 2015 Overgeneral memory, where individuals exhibit difficulties in retrieving specific episodes from autobiographical memory, has been consistently linked with emotional disorders. However, the majority of this literature has relied upon a single methodology,
Anderson, Rachel J. +2 more
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Modulation of adult-born neurons in the inflamed hippocampus. [PDF]
, 2013 Throughout life new neurons are continuously added to the hippocampal circuitry involved with spatial learning and memory. These new cells originate from neural precursors in the subgranular zone of the dentate gyrus, migrate into the granule cell layer,
Belarbi, Karim, Rosi, Susanna
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Protocol for single-nucleus ATAC sequencing and bioinformatic analysis in frozen human brain tissue
STAR Protocols, 2022 Summary: Single-nucleus ATAC sequencing (snATAC-seq) employs a hyperactive Tn5 transposase to gain precise information about the cis-regulatory elements in specific cell types. However, the standard protocol of snATAC-seq is not optimized for all tissues,
Zechuan Shi +4 more
doaj +1 more source
Augev Method and an Innovative Use of Vocal Spectroscopy in Evaluating and Monitoring the Rehabilitation Path of Subjects Showing Severe Communication Pathologies [PDF]
, 2019 A strongly connotative element of developmental disorders (DS) is the total or partial impairment of verbal communication and, more generally, of social interaction.
Bosna, Vittoria +6 more
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