Results 71 to 80 of about 2,782,098 (300)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Vestnik KRAUNC: Fiziko-Matematičeskie NaukiВ статье представлено исследование вычислительной эффективности гибридного параллельного алгоритма, реализующего нелокальную неявную конечно-разностную схему (IFDS) для численного решения задачи динамики объемной активности радона (ОАР).
Твёрдый, Д.А.
doaj +1 more source
Constructing a coarse-grained water model based on non-Markovian dissipative particle dynamics
Nihon Kikai Gakkai ronbunshu, 2018 We constructed a coarse-grained (CG) water model based on non-Markovian dissipative particle dynamics (NMDPD) taking into account memory effects. The NMDPD equation of motion was derived from a generalized Langevin equation formulated via the Mori ...
Gengo KIHARA +4 more
doaj +1 more source
Contribution of Ultra-Fine Bubbles to Promoting Effect on Propane Hydrate Formation
Frontiers in Chemistry, 2020 To investigate experimentally how ultra-fine bubbles (UFBs) may promote hydrate formation, we examined the formation of propane (C3H8) hydrate from UFB-infused water solution using two preparation methods.
Tsutomu Uchida +5 more
doaj +1 more source
The effect of spatial learning on the number of astrocytes in rat dentate gyrus [PDF]
, 2007 In this study, we evaluated the effect of spatial learning on the number of astrocytes in the rat dentate gyrus with Morris water maze. Fifteen male albino Wistar rats were divided into three groups as control, reference memory and working memory groups.
Hosseini, A. +3 more
core
Temperature memory effect/triple-shape memory effect in niti shape memory alloys and shape memory effect in keratin [PDF]
, 2019 Besides the shape memory effect (SME), in which the permanent shape can be recovered at the presence of the right stimulus, the temperature memory effect (TME) is another feature of shape memory materials. The TME refers to a phenomenon that a particular temperature can be memorized in a certain manner.
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
IEEE AccessThe global outbreak of Monkeypox has emerged as a significant concern in recent years, as per the World Health Organization (WHO). It is essential to study the transmission dynamics of the disease to project its progression and design future mitigation ...
Chinwe Peace Igiri, Samuel Shikaa
doaj +1 more source
Subsequent memory effects in schizophrenia [PDF]
Psychiatry Research: Neuroimaging, 2014 Differential neural activation at encoding can predict which stimuli will be subsequently remembered or forgotten, and memory deficits are pronounced in schizophrenia. We used event-related functional magnetic resonance imaging (fMRI) to investigate subsequent memory (SM) effects for visual fractals in patients with schizophrenia (n=26) and healthy ...
Azurii K, Collier +4 more
openaire +2 more sources