Results 61 to 70 of about 11,896,249 (305)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A method to determine the accuracy of shape setting thin, spirally shaped Nitinol wires

open access: yesCurrent Directions in Biomedical Engineering, 2021
Electric stimulation of the auditory nerve using a cochlear implant (CI) is presumed to be superior when the electrode array (EA) is placed close to the inner wall of the cochlea. Nitinol is investigated as an actuator that enables an intracochlear shape
Ehmann Tim   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Equivalence between a time-fractional and an integer-order gradient flow: The memory effect reflected in the energy

open access: yesAdvances in Nonlinear Analysis, 2022
Time-fractional partial differential equations are nonlocal-in-time and show an innate memory effect. Previously, examples like the time-fractional Cahn-Hilliard and Fokker-Planck equations have been studied.
Fritz Marvin   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Determination of Total Mercury in Gold-loaded Carbon by Solid Mercury Analyzer

open access: yesYankuang ceshi, 2016
Gold-loaded carbon has a strong adsorption ability of mercury, which will result in the pollution of the gold extraction process and reduce the absorption of gold by activated carbon.
LUO Rong-gen
doaj   +1 more source

Entanglement Dynamics of Coupled Quantum Oscillators in Independent NonMarkovian Baths

open access: yesEntropy, 2022
This work strives to better understand how the entanglement in an open quantum system, here represented by two coupled Brownian oscillators, is affected by a nonMarkovian environment (with memories), here represented by two independent baths each ...
Jen-Tsung Hsiang   +2 more
doaj   +1 more source

Memory Conformity Effect

open access: yes
The chapter discusses the most important areas of research on the memory conformity effect, which involves the inclusion of incorrect information (misinformation) in memory accounts concerning a particular event obtained by a witness as a result of another witness’s account of the same event.
Kękuś, Magdalena   +2 more
openaire   +3 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Self-rated everyday prospective memory abilities of cigarette smokers and non-smokers: a web based study [PDF]

open access: yes, 2005
The present study examined self-ratings of two aspects of everyday memory performance: long-term prospective memory—measured by the prospective memory questionnaire (PMQ), and everyday memory—measured by the everyday memory questionnaire (EMQ).
Buchanan, Tom   +11 more
core   +1 more source

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