Results 81 to 90 of about 2,782,098 (300)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The effect of Midazolam and Propranolol on fear memory reconsolidation in ethanol-withdrawn rats: Influence of D-cycloserine [PDF]
, 2014 Background: Withdrawal from chronic ethanol facilitates the formation of contextual fear memory and delays the onset to extinction, with its retrieval promoting an increase in ethanol consumption.
Espejo, Pablo Javier +4 more
core +1 more source
Spacing effects in picture memory [PDF]
Memory & Cognition, 1973 Three experiments were conducted to capitalize on the conclusion of Shaffer and Shiffrin (1972) that complex visual scenes are not rehearsed in testing the hypothesis that the effect of spacing on memory is due to rehearsal. In Experiment I, a list of vacation slides was presented in which both the number of repetitions and the spacing of repetitions ...
D L, Hintzman, M K, Rogers
openaire +2 more sources
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Exercise Does Not Effect Context-dependent Episodic Memory [PDF]
, 2019 Memory has been shown to be strongly associated with the context in which it is encoded, suggesting that the context is central to the memory itself. However, the effect of exercise on context dependent object recognition is not fully known.
Greenberg, Michael D.
core +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Vestnik KRAUNC: Fiziko-Matematičeskie NaukiРадон — инертный радиоактивный газ, исследования вариаций которого в сопоставлении с сейсмичностью считаются перспективными для целей разработки методик прогноза землетрясений.
Твёрдый, Д.А. +2 more
doaj +1 more source
On memory effect in modified gravity theories
, 2019 In this note, we discuss the gravitational memory effect in higher derivative and infinite derivative gravity theories and give the detailed relevant calculations whose results were given in our recent works.
Kilicarslan, Ercan
core +1 more source
Effects of memory on the shapes of simple outbreak trees [PDF]
, 2016 Genomic tools, including phylogenetic trees derived from sequence data, are increasingly used to understand outbreaks of infectious diseases. One challenge is to link phylogenetic trees to patterns of transmission.
Boyd, M +3 more
core +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source