Results 1 to 10 of about 24,136 (236)

Genetic background influences tumour development in heterozygous Men1 knockout mice [PDF]

Endocrine Connections, 2020
Multiple endocrine neoplasia type 1 (MEN1), an autosomal domina nt disorder caused by MEN1 germline mutations, is characterised by parathyroid, pancreati c and pituitary tumours.
Kate E Lines, Mahsa Javid, Anita A C Reed, Gerard V Walls, Mark Stevenson, Michelle Simon, Kreepa G Kooblall, Sian E Piret, Paul T Christie, Paul J Newey, Ann-Marie Mallon, Rajesh V Thakker   +11 more
doaj   +6 more sources

Multiple Endocrine Neoplasia Type 1 (MEN1): An Update and the Significance of Early Genetic and Clinical Diagnosis

Frontiers in Endocrinology, 2019
Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary tumor syndrome inherited in an autosomal dominant manner and characterized by a predisposition to a multitude of endocrine neoplasms primarily of parathyroid, enteropancreatic, and anterior ...
Crystal Dawn Chrysavgi Kamilaris, Constantine A Stratakis   +1 more
exaly   +3 more sources

Case Report: A novel likely pathogenetic variant of the <i>MEN1</i> gene in multiple endocrine neoplasia type 1. [PDF]

Front Endocrinol (Lausanne)
BackgroundMultiple endocrine neoplasia type 1 (MEN1) is a rare disease caused by mutations in the oncosuppressor gene MEN1 and characterized by co-occurrence of tumors of the parathyroid gland, pancreas, and pituitary gland.
Sun M, Chang X, Huang X, Chen L, Peng M, Zhong X.   +5 more
europepmc   +2 more sources

Pituitary Disease in MEN Type 1 (MEN1): Data from the France-Belgium MEN1 Multicenter Study [PDF]

Journal of Clinical Endocrinology and Metabolism, 2002
Bruno Vergès, Albert Beckers
exaly   +2 more sources

O-12 A RARE MEN1 CASE WITH MULTIHORMONAL SECRETION AND THYMIC NEUROENDOCRINE TUMOR WITH METASTATIC PROGRESSION [PDF]

JCEM Case Rep
Ferhan Mantar, Fatih SELÇUKBİRİCİK
europepmc   +2 more sources

Synapse formation between central neurons requires postsynaptic expression of the MEN1 tumor suppressor gene [PDF]

, 2001
Bouwman, J., Feng, Z.P., Geraerts, W.P.M., Kesteren, R.E. van, Munno, D.W., Smit, A.B., Syed, N.I.   +6 more
core   +4 more sources

Cutaneous lesions and other non-endocrine manifestations of Multiple Endocrine Neoplasia type 1 syndrome

Frontiers in Endocrinology, 2023
BackgroundMultiple Endocrine Neoplasia type 1 is a rare genetic syndrome mainly caused by mutations of MEN1 gene and characterized by a combination of several endocrine and non-endocrine manifestations.
Laura Pierotti, Elena Pardi, Elisa Dinoi, Paolo Piaggi, Simona Borsari, Simone Della Valentina, Chiara Sardella, Angela Michelucci, Maria Adelaide Caligo, Fausto Bogazzi, Claudio Marcocci, Claudio Marcocci, Filomena Cetani   +12 more
doaj   +1 more source

Systematic detection of mosaicism by using digital NGS reveals three new MEN1 mosaicisms

Endocrine Connections, 2022
Purpose: Mosaicism is a feature of several inherited tumor syndromes. Only a few cases of mosaicism have been described in multiple endocrine neoplasia type 1 (MEN1).
Arnaud Lagarde, Grégory Mougel, Lucie Coppin, Magalie Haissaguerre, Lauriane Le Collen, Amira Mohamed, Marc Klein, Marie-Françoise Odou, Antoine Tabarin, Hedia Brixi, Thomas Cuny, Brigitte Delemer, Anne Barlier, Pauline Romanet   +13 more
doaj   +1 more source

Mutational and large deletion study of genes implicated in hereditary forms of primary hyperparathyroidism and correlation with clinical features. [PDF]

PLoS ONE, 2017
The aim of this study was to carry out genetic screening of the MEN1, CDKN1B and AIP genes, both by direct sequencing of the coding region and multiplex ligation-dependent probe amplification (MLPA) assay in the largest monocentric series of Italian ...
Elena Pardi, Simona Borsari, Federica Saponaro, Fausto Bogazzi, Claudio Urbani, Stefano Mariotti, Francesca Pigliaru, Chiara Satta, Fabiana Pani, Gabriele Materazzi, Paolo Miccoli, Lorena Grantaliano, Claudio Marcocci, Filomena Cetani   +13 more
doaj   +1 more source

Prevalence of Parathyroid Carcinoma and Atypical Parathyroid Neoplasms in 153 Patients With Multiple Endocrine Neoplasia Type 1: Case Series and Literature Review

Frontiers in Endocrinology, 2020
Purpose: The occurrence of parathyroid carcinoma (PC) and atypical parathyroid neoplasm (APN) in multiple endocrine neoplasia type 1 (MEN1) is rare. The present paper reports the cases of 3 MEN1-PC/APN patients at our center and discusses the prevalence ...
An Song, Yi Yang, Shuzhong Liu, Min Nie, Yan Jiang, Mei Li, Weibo Xia, Ou Wang, Xiaoping Xing   +8 more
doaj   +1 more source