Results 21 to 30 of about 12,302 (171)

Beyond the “3 Ps”: A critical appraisal of the non-endocrine manifestations of multiple endocrine neoplasia type 1

Frontiers in Endocrinology, 2022
Multiple endocrine neoplasia type 1 (MEN1), an autosomal-dominantly inherited tumor syndrome, is classically defined by tumors arising from the “3 Ps”: Parathyroids, Pituitary, and the endocrine Pancreas.
Steven G. Waguespack
doaj   +1 more source

A large Turkish pedigree with multiple endocrine neoplasia type 1 syndrome carrying a rare mutation: c.1680_1683 del TGAG

The Turkish Journal of Gastroenterology, 2020
Background & Aims: Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome characterized by tumors arising from endocrine glands with no specific genotype-phenotype correlation. Herein, we report the largest Turkish kindred with MEN1
Coşkun Özer Demirtaş, Pınar Ata, Ali Çetin, Ayberk Türkyılmaz, Deniz Guney Duman   +4 more
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Adrenocortical carcinoma in patients with MEN1: a kindred report and review of the literature

Endocrine Connections, 2019
Objective: Up to 40% of multiple endocrine neoplasia type 1 (MEN1) patients may have adrenal cortical tumors. However, adrenocortical carcinoma (ACC) is rare.
Weixi Wang, Rulai Han, Lei Ye, Jing Xie, Bei Tao, Fukang Sun, Ran Zhuo, Xi Chen, Xiaxing Deng, Cong Ye, Hongyan Zhao, Shu Wang   +11 more
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MEN1 promotes ferroptosis by inhibiting mTOR-SCD1 axis in pancreatic neuroendocrine tumors

Acta Biochimica et Biophysica Sinica, 2022
Pancreatic neuroendocrine tumor (pNET) is the second most common malignant tumors of the pancreas. Multiple endocrine neoplasia 1 ( MEN1) is the most frequently mutated gene in pNETs and MEN1-encoded protein, menin, is a scaffold ...
Ye Zeng, Chen Haidi, Ji Shunrong, Hu Yuheng, Lou Xin, Zhang Wuhu, Jing Desheng, Fan Guixiong, Zhang Yue, Chen Xuemin, Zhuo Qifeng, Chen Jie, Xu Xiaowu, Yu Xianjun, Xu Jin, Qin Yi, Gao Heli   +16 more
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MEN1-dependent breast cancer: indication for early screening? Results from the Dutch MEN1 study group. [PDF]

, 2017
Objective: Multiple Endocrine Neoplasia type 1 (MEN1) is associated with an early onset elevated breast cancer risk. This finding potentially has implications for breast cancer screening for females with MEN1. Considering the impact for females with MEN1,
Vriens, M.R., Menno R. Vriens, Horst-Schrivers, A.N. van der, Dreijerink, Koen M, Bas Havekes, Petra H. M. Peeters, Bisschop, P.H., Ausems, MG, Van Leeuwaarde, Rachel S., Bisschop, Peter H, Peeters, Petra H.M., Vriens, Menno R, Peeters, P.H.M., Peeters, PH, Olaf M. Dekkers, Drent, M.L. (Madeleine), Madeleine L. Drent, Pijnappel, R.M., Dreijerink, K, Dekkers, O.M. (Olaf), Beijers, H.J. (Hanneke J.), Drent, Madeleine L, Drent, Madeleine L., Beijers, HJ, Vriens, M.R. (Menno), Dreijerink, Koen M., Peeters, Petra H M, Pijnappel, RM, Vriens, MR, de Herder, WW, Havekes, B. (Bas), Valk, G.D., Herder, W.W. de, Valk, Gerlof D, Van Leeuwaarde, R.S. (Rachel S.), Dreijerink, K.M. (Koen M.), Ausems, M.G., Pijnappel, Ruud M., Peter H. Bisschop, Pijnappel, Ruud M, Ruud M. Pijnappel, Peeters, Petra H. M., Herder, W.W. (Wouter) de, Dreijerink, Koen M. A., Dreijerink, K.M., van der Horst-Schrivers, Anouk N., van Leeuwaarde, Rachel S, Anouk N. van der Horst-Schrivers, de Herder, W.W., Havekes, B, Koen M. Dreijerink, Ausems, Margreet G, Bisschop, Peter H., Valk, G.D. (Gerlof), Horst-Schrivers, A.N.A. (Anouk) van der, Wouter W. de Herder, Drent, M.L., Beijers, Hanneke J., van Leeuwaarde, RS, Ausems, Margreet G., Leeuwaarde, R.S. van, Dekkers, Olaf M., Bisschop, P.H. (Peter), Beijers, H.J., van der Horst-Schrivers, AN, Bisschop, PH, Ausems, M.G.E.M. (Margreet), Hanneke J. Beijers, Drent, ML, Dekkers, O.M., Dreijerink, KM, Dekkers, Olaf M, Havekes, Bas, Valk, Gerlof D., Dekkers, OM, Margreet G. Ausems, Peeters, PHM, de Herder, Wouter W., Gerlof D. Valk, van der Horst-Schrivers, Anouk N, Rachel S. van Leeuwaarde, Havekes, B., Vriens, Menno R., de Herder, Wouter W, de Herder, Wouter, Beijers, Hanneke J, Valk, GD, Pijnappel, W.W.M.P. (Pim)   +87 more
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Pituitary disease in MEN type 1 (MEN1): Data from the France-Belgium MEN1 multicenter study [PDF]

, 2002
peer reviewedTo date, data on pituitary adenomas in MEN type 1 (MEN1) still have to be evaluated. We analyzed the data of a large series of 324 MEN1 patients from a French and Belgian multicenter study.
Boureille, F., Sassolas, G., Montvernay, C., Chambe, B., Cougard, P., Goudet, P., Murat, A., Calender, A., Vergès, B., Beckers, Albert   +9 more
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Multiple endocrine neoplasia type 1

Indian Journal of Endocrinology and Metabolism, 2012
Multiple endocrine neoplasia type 1 (MEN1) is characterized by the occurrence of parathyroid, pancreatic islet and anterior pituitary tumors. Some patients may also develop carcinoid tumors, adrenocortical tumors, facial angiofibromas, collagenomas, and ...
R V Thakker
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MEN1 surveillance guidelines : time to (re)think? [PDF]

, 2022
Clinical practice guidelines for patients with multiple endocrine neoplasia type 1 (MEN1) recommend a variety of surveillance options. Given progress over the past decade in this area, it is timely to evaluate their ongoing utility. MEN1 is characterized
Newell-Price, J., Newey, P.J., Newey, Paul J., Newell-Price, John   +3 more
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The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth.

PLoS ONE, 2015
Multiple endocrine neoplasia type 1 (MEN1) is a genetic disorder characterized by tissue-specific tumors in the endocrine pancreas, parathyroid, and pituitary glands.
Wendy M McKimpson, Ziqiang Yuan, Min Zheng, Judy S Crabtree, Steven K Libutti, Richard N Kitsis   +5 more
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Impact of Delay in Diagnosis in Outcomes in MEN1: Results From the Dutch MEN1 Study Group [PDF]

, 2016
Contains fulltext : 172749.pdf (Publisher’s version ) (Open Access)OBJECTIVE: Identifying a germline mutation in the multiple endocrine neoplasia type 1 (MEN1) gene in an index case has consequences for a whole family.
Vriens, M.R., van Nesselrooij, BPM, Horst-Schrivers, A.N. van der, Bisschop, P.H., van Nesselrooij, Bernadette P. M., Bisschop, Peter H, Hermus, Ad R, Laat, J.M. de, Vriens, Menno R, de Laat, JM, van Nesselrooij, Bernadette P M, Drent, Madeleine L, Drent, Madeleine L., Pieterman, Carolina R C, Nesselrooij, B.P. van, Vriens, MR, Valk, G.D., Herder, W.W. de, Valk, Gerlof D, Van Leeuwaarde, RS, Nesselrooij, B.P.M. van, Hermus, A.R., van Leeuwaarde, Rachel S, Hermus, Ad R., van der Horst-Schrivers, Anouk N., Pieterman, Carolina R. C., de Herder, W.W., Pieterman, C.R.C., Havekes, B, Bisschop, Peter H., de Laat, Joanne M, Drent, M.L., Leeuwaarde, R.S. van, Dekkers, Olaf M., Hermus, AR, Pieterman, CRC, van der Horst-Schrivers, AN, Pieterman, C.R., Bisschop, PH, Dekkers, O.M., Drent, ML, van Leeuwaarde, Rachel S., Dekkers, Olaf M, Havekes, Bas, Valk, Gerlof D., Dekkers, OM, de Herder, Wouter W., van der Horst-Schrivers, Anouk N, Havekes, B., Vriens, Menno R., de Herder, Wouter W, de Laat, Joanne M., Valk, GD   +52 more
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