Results 41 to 50 of about 3,490 (181)
Clinical Medicine Insights: Endocrinology and Diabetes, 2017 Mutations in the VHL, RET, SDHB , and SDHD genes are responsible for von Hippel-Lindau (VHL) disease, multiple endocrine neoplasia type 2 (MEN2), and familial paraganglioma, respectively.
Chutintorn Sriphrapradang +3 more
doaj +1 more source
A novel mutation identified in a patient with pheochromocytoma and renal cell carcinoma [PDF]
Kosin Medical Journal, 2018 Pheochromocytomas might be sporadic or genetic. Genetic pheochromocytoma is associated with multiple endocrine neoplasia (MEN) type 2A, MEN type 2B, and von Hippel-Lindau (VHL) disease. RET mutations are identified in more than 90% of index cases of MEN2
Jae Wan Kwon +5 more
doaj +1 more source
Endocrine Connections, 2021 Risk of metastatic disease in the cluster 2-related pheochromocytoma/paraganglioma (PPGL) is low. In MEN2 patients, identification of origin of met astases from pheochromocytoma (PCC) or medullary thyroid carcinoma (MTC) is challenging as both are of ...
Sandeep Kumar +10 more
doaj +1 more source
Role of VEGF-A and Its Receptors in Sporadic and MEN2-Associated Pheochromocytoma [PDF]
International Journal of Molecular Sciences, 2014 Pheochromocytoma (PHEO), a rare catecholamine producing tumor arising from the chromaffin cells, may occurs sporadically (76%–80%) or as part of inherited syndromes (20%–24%). Angiogenesis is a fundamental step in tumor proliferation and vascular endothelial growth factor (VEGF-A) is the most well-characterized angiogenic factor. The role of angiogenic
Ferreira, Carla Vaz +7 more
openaire +3 more sources
A Case of Multiple Endocrine Neoplasia Type 2B and Gangliomatosis of Gastrointestinal Tract
Case Reports in Medicine, 2012 Multiple endocrine neoplasia type 2 (MEN2) is a rare familial syndrome caused by mutations in the RET protooncogene and it is transmitted as an autosomal dominant trait.
Banafshe Shahnazari +5 more
doaj +1 more source
Management of hyperparathyroidism (PHP) in MEN2 syndromes in Europe [PDF]
Thyroid Research, 2013 Hyperparathyroidism occurs in 20-30% of MEN2A syndrome patients. It is usually associated with mild disease and is frequently asymptomatic, especially in younger age. There is genotype/phenotype association and PHP is usually associated with codon 634 mutations; however association with more "rare" mutations has also been reported. The pathology of the
openaire +2 more sources
Head &Neck, EarlyView.ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent +15 more
wiley +1 more source
International Journal of Applied Linguistics, EarlyView.ABSTRACT Teacher well‐being has garnered increasing attention in language education, as it plays a vital role in shaping both their professional lives and student learning. Although its importance is recognised, further research is still needed to gain a more comprehensive understanding of language teachers' well‐being.
Takeshi Onodera
wiley +1 more source
Diagnosis of pheochromocytoma with special emphasis on MEN2 syndrome
Hormones, 2009 Pheochromocytomas/paragangliomas(PHEOs/PGLs) are rare but treacherous catecholamine-producing tumors which, if overlooked or improperly treated, will almost invariably prove fatal. Patients with MEN2 PHEOs have a high incidence of paroxysmal attacks and a higher prevalence of hypertension and other cardiovascular problems than do patients with Von ...
Karel, Pacak +2 more
openaire +2 more sources