Results 31 to 40 of about 3,490 (181)

RMRP, RMST, FTX and IPW: novel potential long non-coding RNAs in medullary thyroid cancer

Orphanet Journal of Rare Diseases, 2021
The relevant role of long non-coding RNAs (lncRNAs) in cancer is currently a matter of increasing interest. Medullary thyroid cancer (MTC) is a rare neuroendocrine tumor (2–5% of all thyroid cancer) derived from the parafollicular C-cells which secrete ...
Berta Luzón-Toro, Leticia Villalba-Benito, Raquel María Fernández, Ana Torroglosa, Guillermo Antiñolo, Salud Borrego   +5 more
doaj   +1 more source

Spectrum of Germline RET variants identified by targeted sequencing and associated Multiple Endocrine Neoplasia type 2 susceptibility in China

BMC Cancer, 2021
Background Germline RET mutations and variants are involved in development of multiple endocrine neoplasia type 2 (MEN2). The present study investigated a spectrum of RET variants, analyzed genotype-phenotype relationships, and evaluated their effect on ...
Xiao-Ping Qi, Jian-Qiang Zhao, Xu-Dong Fang, Bi-Jun Lian, Feng Li, Hui-Hong Wang, Zhi-Lie Cao, Wei-Hui Zheng, Juan Cao, Yu Chen   +9 more
doaj   +1 more source

I tempi della tiroidectomia nella MEN2 [PDF]

L'Endocrinologo, 2021
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Alessandro Prete, Rossella Elisei
openaire   +2 more sources

Synchronized Laparoscopic Bilateral Adrenalectomy for Pheochromocytoma in Multiple Endocrine Neoplasia Syndrome: A Case Report

Journal of Kidney Cancer and VHL, 2022
Pheochromocytomas are tumors producing catecholamines that arise from chromaffin cells in the adrenal medulla. They are usually benign in multiple endocrine neoplasia type 2 (MEN2) syndrome, but they tend to present bilaterally in 50–80% of the patients.
Ali Eslahi, Shahryar Zeighami, Faisal Ahmed, Seyed Hossein Hosseini, Bahareh Ebrahimi, Mohammad Hossein Anbardar   +5 more
doaj   +1 more source

Streamlining Thyroidectomy Treatment with a Multidisciplinary Approach: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2023
Multiple Endocrine Neoplasia 2 (MEN2) is a rare genetic disorder that affects the endocrine glands and can lead to the development of tumours in the thyroid gland, parathyroid gland, and adrenal glands.
Avilash Mohapatra, Deepanshi Vashishtha, Srikanta Padhan   +2 more
doaj   +1 more source

Multiple endocrine neoplasia type 2

Orphanet Journal of Rare Diseases, 2006
Multiple Endocrine Neoplasia Type 2 (MEN2) is a rare hereditary complex disorder characterized by the presence of medullary thyroid carcinoma (MTC), unilateral or bilateral pheochromocytoma (PHEO) and other hyperplasia and/or neoplasia of different ...
Luzi Ettore, Tognarini Isabella, Carbonell Sala Silvia, Del Monte Francesca, Falchetti Alberto, Marini Francesca, Brandi Maria   +6 more
doaj   +1 more source

Looking beyond the thyroid: advances in the understanding of pheochromocytoma and hyperparathyroidism phenotypes in MEN2 and of non-MEN2 familial forms [PDF]

Endocrine-Related Cancer, 2018
Over the last years, the knowledge of MEN2 and non-MEN2 familial forms of pheochromocytoma (PHEO) has increased. In MEN2, PHEO is the second most frequent disease: the penetrance and age at diagnosis depend on the mutation of RET .
Guerin, Carole, Romanet, Pauline, Taieb, David, Brue, Thierry, Lacroix, André, Sebag, Frédéric, Barlier, Anne, Castinetti, Frederic   +7 more
openaire   +3 more sources

Simultaneous bilateral laparoscopic cortical-sparing adrenalectomy for bilateral pheochromocytomas in multiple endocrine neoplasia type 2

Frontiers in Surgery, 2023
PurposeThis study aimed to assess the feasibility of synchronous bilateral laparoscopic or open cortical-sparing adrenalectomy (SB-LCSA or SB-OCSA) for bilateral pheochromocytomas (bPHEOs) in multiple endocrine neoplasia type 2 (MEN2).MethodsAltogether ...
Xiao-Ping Qi, Bi-Jun Lian, Xu-Dong Fang, Fang Dong, Feng Li, Hang-Yang Jin, Ke Zhang, Kang-Er Wang, Yi Zhang   +8 more
doaj   +1 more source

Neoplasias endócrinas múltiplas.

Acta Médica Portuguesa, 2007
The knowledge of genetics has increased in recent years and has led to important changes in management of hereditary diseases. Multiple endocrine neoplasia is characterized by the occurrence of benign or malign tumours involving two or more endocrine ...
Joana Guimarães
doaj   +1 more source

Prevalence and genetics of "de novo" MEN2 syndromes.

J Clin Endocrinol Metab
Abstract Context Hereditary medullary thyroid carcinoma (MTC) is an inherited syndrome accounting for 25% of MTC cases. It is caused by germline RET mutations, which can be inherited or occur de novo.
Casalini R, Romei C, Bottici V, Cappagli V, Tascini V, Matrone A, Prete A, Ciampi R, Ramone T, Elisei R.   +9 more
europepmc   +3 more sources