Results 121 to 130 of about 143,068 (301)
Outlier Detection in Mendelian Randomization
Statistics in MedicineABSTRACT Mendelian randomization (MR) uses genetic variants as instrumental variables to infer causal effects of exposures on an outcome. One key assumption of MR is that the genetic variants used as instrumental variables are independent of the outcome conditional on the risk factor and unobserved confounders.
Maximilian M. Mandl +3 more
openaire +4 more sources
Mendelian Randomization Steiger test results
Mendelian Randomization Steiger test ...
X, X
core +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Cancer survivors frequently experience cancer‐related cognitive impairment (CRCI), but the contributions of different anti‐cancer therapies remain unclear. Patients with breast or gynaecological cancer were recruited before any anti‐cancer treatment.
Qiqi Lei +5 more
wiley +1 more source
A Bidirectional Mendelian Randomization Study of Sarcopenia-Related Traits and Knee Osteoarthritis
, 2023 Longyao Zhang,1,2,* Chao Zhang,1,2,* Juntao Zhang,1,2 Aifeng Liu,1,2 Ping Wang,1,2 Jiankang Xu1,2 1Orthopedics Department, the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China ...
Wang P +5 more
core
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng +4 more
wiley +1 more source
Mendelian Randomization Analysis Supports a Causal Relationship Between Circulating Inflammatory Proteins and Basal Cell Carcinoma [PDF]
Zhi-da Fu,1,2,* Yao Wang,3,* Hong-li Yan,2 Jian-hua Wu1 1Department of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China; 2Center for Reproductive Medicine, Changhai Hospital, Naval Medical University,
Yan HL, Fu ZD, Wang Y, Wu JH
core
The womb as the cradle of longevity: Perinatal origins of biological aging
International Journal of Gynecology &Obstetrics, EarlyView.Abstract The perinatal period is increasingly recognized as an important determinant of biological aging trajectories and disease susceptibility across the lifespan. This narrative review synthesizes current evidence linking intrauterine exposures to adult health outcomes across three biological dimensions: fetal programming, maternal influences, and ...
Sevim Ozge Ozdemir, Ebru Davutoglu
wiley +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Journal of Multidisciplinary HealthcarePengfei Liu,1 Qiurong Zeng2 1Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan, People’s Republic of China; 2Department of Laboratory Medicine, North Sichuan Medical College, Nanchong, Sichuan, People’s Republic of ...
Liu P, Zeng Q
doaj
Frontiers in EndocrinologyBackgroundMendelian randomization is believed to attenuate the biases inherent in observational studies, yet a meta-analysis of Mendelian randomization studies in osteoporosis has not been conducted thus far.
Wenhao Ji +11 more
doaj +1 more source