Results 151 to 160 of about 51,589 (295)

The effect of non-differential measurement error on bias, precision and power in Mendelian randomization studies [PDF]

, 2014
B. L. Pierce, Tyler J. VanderWeele
openalex   +1 more source

Temporal niche differentiation often leads to priority effects rather than coexistence: Lessons from a marine midge

Journal of Animal Ecology, EarlyView.
When organisms use similar resources but at a different time, it is not obvious whether they can divide their temporal niches in a coexistence promoting manner or of something else should happen. This study shows that priority effects are a likely, but not self‐evident, outcome.
Runa K. Ekrem, Charlotte de Vries, Tobias S. Kaiser, Hanna Kokko   +3 more
wiley   +1 more source

Functional validation of a white pupae minimal gene construct in Ceratitis capitata (Diptera: Tephritidae)

Insect Science, EarlyView.
An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates, Roswitha A. Aumann, Inga Sievers, Tanja Rehling, Marc F. Schetelig   +4 more
wiley   +1 more source

Mendelian randomization of serum urate and parkinson disease progression [PDF]

, 2014
Kelly Claire Simon, Shirley Eberly, Xiang Gao, David Oakes, Caroline M. Tanner, Ira Shoulson, Stanley Fahn, Michael A. Schwarzschild, Alberto Ascherio   +8 more
openalex   +1 more source

Multi‐Omic Associations of Epigenetic Age Acceleration Are Heterogeneously Shaped by Genetic and Environmental Influences

Aging Cell, EarlyView.
The connections between epigenetic age acceleration (EAA) and the multi‐ome, as well as the extent to which these connections are driven by genetic and environmental factors, remain underexplored. We identified blood proteins, metabolites, and exposures associated with EAA in young adults and, using twin study designs, show that these associations are ...
Gabin Drouard, Sannimari Suhonen, Aino Heikkinen, Zhiyang Wang, Jaakko Kaprio, Miina Ollikainen   +5 more
wiley   +1 more source

MR-PheWAS: hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization [PDF]

, 2015
Louise A C Millard, Neil M Davies, Nicholas J. Timpson, Kate Tilling, Peter Flach, George Davey Smith   +5 more
openalex   +1 more source

Dietary Selenium Deficiency Accelerates the Onset of Aging‐Related Gut Microbial Changes in Aged Telomere‐Humanized Mice, With Akkermansia muciniphila Being the Most Prominent and Alleviating Selenium Deficiency‐Induced Type 2 Diabetes

Aging Cell, EarlyView.
Gut Akkermansia muciniphila is enriched by dietary selenium deficiency in aged telomere‐humanized mice and counteracts dietary selenium deficiency‐induced type 2 diabetes. ABSTRACT Previous studies have shown that dietary selenium (Se) deficiency in mice reshapes gut microbiota, exacerbates healthspan deterioration (e.g., type 2 diabetes), and ...
Ying‐Chen Huang, Hsin‐Yi Lu, Li Zhang, Alicia Olivier, Tung‐Lung Wu, Chuan‐Yu Hsu, Caleb LeGrand, Huawei Zeng, Samantha Curran, Qingzhou Wang, Ramakrishna Nannapaneni, Xue Zhang, Max Ticó, Marco Mariotti, Ryan T. Y. Wu, Gerald F. Combs Jr, Wen‐Hsing Cheng   +16 more
wiley   +1 more source

Exploring the relationship between maternal iron status and offspring’s blood pressure and adiposity: a Mendelian randomization study

, 2012
Nisreen A Alwan, Debbie A. Lawlor, McArdle, Greenwood, Cade   +4 more
openalex   +2 more sources

Milk intake is not associated with low risk of diabetes or overweight-obesity: a Mendelian randomization study in 97,811 Danish individuals [PDF]

, 2015
Helle K M Bergholdt, Børge G. Nordestgaard, Christina Ellervik   +2 more
openalex   +1 more source

Microbiological Foundations to Optimise Intrinsic Capacity and Promote Healthy Ageing: An Integration Into the Life Course Approach

Aging Cell, EarlyView.
Gut microbiota composition may influence trajectories of intrinsic capacity throughout life. Factors that positively or negatively impact gut microbiota (determining eubiosis or dysbiosis, respectively) can affect health, potentially acting through short‐chain fatty acids and their metabolic and anti‐inflammatory functions.
Christoph Benner, Matteo Cesari, Ritu Sadana   +2 more
wiley   +1 more source