Mendelian randomization of serum urate and parkinson disease progression [PDF]
Kelly Claire Simon+8 more
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Noise and the risk of tinnitus: A two‐sample Mendelian randomized study
Abstract Objectives Observational studies imply that noise may increase the likelihood of developing tinnitus. However, no causal relationship has been established between the two using Mendelian randomization (MR) analysis, we aimed to determine the potential causal relationship between noise and various categories of tinnitus.
He‐Sen Huang+6 more
wiley +1 more source
The association between plasminogen activator inhibitor type 1 (PAI-1) levels, PAI-1 4G/5G polymorphism, and myocardial infarction: a Mendelian randomization meta-analysis [PDF]
Georgios K. Nikolopoulos+8 more
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ABSTRACT Objective Assessment of whether maternal anaemia in early pregnancy is associated with offspring congenital heart disease (CHD). Design Matched case–control study. Setting January 1998–October 2020, United Kingdom. Population Women with a haemoglobin measurement in the first 100 days of pregnancy and a CHD‐diagnosed child.
Manisha Nair+4 more
wiley +1 more source
YKL-40 and Alcoholic Liver and Pancreas Damage and Disease in 86258 Individuals from the General Population: Cohort and Mendelian Randomization Studies [PDF]
Alisa D. Kjærgaard+3 more
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Instrumental variables in the cost of illness featuring type 2 diabetes
Abstract Objective To ascertain how an instrumental variables (IV) model can improve upon the estimates obtained from traditional cost‐of‐illness (COI) models that treat health conditions as predetermined. Study Setting and Design A simulation study based on observational data compares the coefficients and average marginal effects from an IV model to a
Kyle Kole+6 more
wiley +1 more source
Examining the causal association of fasting glucose with blood pressure in healthy children and adolescents: a Mendelian randomization study employing common genetic variants of fasting glucose [PDF]
Tina S. Goharian+9 more
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The introgression of a synthetic sex ratio distortion transgene into two different genetic backgrounds of Anopheles coluzzii by six backcrosses. We showed that the phenotype of the sex ratio distorter is stabile in the introgressed An. coluzzii strains.
Paola Pollegioni+13 more
wiley +1 more source
Low Nonfasting Triglycerides and Reduced All-Cause Mortality: A Mendelian Randomization Study [PDF]
Mette Thomsen+3 more
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The effect of non-differential measurement error on bias, precision and power in Mendelian randomization studies [PDF]
B. L. Pierce, Tyler J. VanderWeele
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