Results 201 to 210 of about 51,589 (295)

Causal relationship between immune mediators and parkinson's disease: A Mendelian randomization analysis. [PDF]

Sci Rep
Qiu R, Su Y, Pan L, Fan K, Sun Z, Liang Y, Lin X, Zhang Y.   +7 more
europepmc   +1 more source

Liver Enzymes and Risk of Ischemic Heart Disease and Type 2 Diabetes Mellitus: A Mendelian Randomization Study [PDF]

, 2016
Junxi Liu, Shiu Lun Au Yeung, Shi Lin Lin, GM Leung, C. Mary Schooling   +4 more
openalex   +1 more source

N‐lactoyl amino acids are potential biomarkers for insulin resistance and diabetic complications

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims N‐lactoyl amino acids (Lac‐AA) are emerging as crucial players in metabolic research, with potential implications for disease mechanisms and therapeutic interventions. This study exploress the role of Lac‐AA in insulin resistance, type 2 diabetes (T2D), and its complications.
Khaled Naja, Asma A. Elashi, Najeha Anwardeen, Aleem Razzaq, Laila Hedaya, Shamma Almuraikhy, Ilhame Diboun, Karsten Suhre, Omar AlBagha, Mohamed A. Elrayess   +9 more
wiley   +1 more source

Genetic Evidence on the Role of Blood Phytosterols in Frailty: A Mendelian Randomization Study. [PDF]

Food Sci Nutr
Gao G, Yao T, Liu C, Fan H, Zhang X, Zhang H, Zhao X, Song B, Wang K, Liu T, Guang X, Zhou Q, Lu W.   +12 more
europepmc   +1 more source

Serum gamma-glutamyl transferase and risk of type 2 diabetes in the general Korean population: a Mendelian randomization study [PDF]

, 2016
Youn Sue Lee, Yoonsu Cho, Stephen Burgess, George Davey Smith, Caroline L. Relton, So-Youn Shin, Min‐Jeong Shin   +6 more
openalex   +1 more source

Clinical whole genome sequencing in pediatric epilepsy: Genetic and phenotypic spectrum of 733 individuals

Epilepsia, EarlyView.
Abstract Objective A large proportion of pediatric epilepsies have an underlying genetic etiology. Limited studies have explored the efficacy of whole genome sequencing (WGS) in a clinical setting. Our academic–clinical center implemented clinical whole exome sequencing (WES) in 2014, then transitioned to WGS from 2015.
Olivia J. Henry, Sofia Ygberg, Michela Barbaro, Nicole Lesko, Leif Karlsson, Lucía Peña‐Pérez, Ann Båvner, Virpi Töhönen, Anna Lindstrand, Tommy Stödberg, Anna Wedell   +10 more
wiley   +1 more source

A comprehensive analysis through Mendelian randomization of immunological markers and sphingolipid metabolism. [PDF]

Discov Oncol
Yang D, Zhang W, Wang Q.
europepmc   +1 more source

Type 2 Diabetes, Diabetes Genetic Score and Risk of Decreased Renal Function and Albuminuria: A Mendelian Randomization Study [PDF]

, 2016
Min Xu, Yufang Bi, Ya Huang, Lan Xie, Mingli Hao, Zhiyun Zhao, Yu Xu, Jieli Lu, Yuhong Chen, Yimin Sun, Lu Qi, Weiqing Wang, Guang Ning   +12 more
openalex   +1 more source

Cannabidiol attenuates epileptic phenotype and increases survival in a mouse model of developmental and epileptic encephalopathy type 1

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathy type 1 (DEE1) is a rare drug‐resistant pediatric epilepsy caused by trinucleotide repeat expansions in the X‐linked ARX gene, leading to elongation of the first polyalanine tract. It presents with early onset tonic seizures or spasms, developmental and cognition delay, and high risk of ...
Lucia Verrillo, Fabio Arturo Iannotti, Denise Drongitis, Katiuscia Martinello, Loredana Poeta, Adriano Barra, Gaetano Terrone, Sergio Fucile, Vincenzo Di Marzo, Maria Giuseppina Miano   +9 more
wiley   +1 more source

Causal Effects of Gut Microbiome on Tinnitus: A Mendelian Randomization Study. [PDF]

J Multidiscip Healthc
Zeng Q, Xie W, Dong H, Liu X, Shao S, Chen L, Zhang W.   +6 more
europepmc   +1 more source