Results 211 to 220 of about 95,337 (328)

Pathogenic Variants in Mennonites From Southern Brazil: Implications for Preventive Measures in Public Health

Clinical Genetics, EarlyView.
In 325 exomes of South Brazilian Mennonites, we identified 23 pathogenic variants (P) and 27 likely P, with founder effects identified for 96% of P, whose frequencies differed from non‐Finnish Europeans, Amish, and Brazilian populations. ABSTRACT The Mennonite population has a unique history of 500 years of genetic isolation shaped by at least three ...
Luiza Beatriz Mayer de Lima, Eduardo Delabio Auer, Isabela Dall’Oglio Bucco, Valéria Bumiller‐Bini Hoch, Priscila Ianzen dos Santos, Fabiana L. Lopes, Alan Shuldiner, Emilton Lima Júnior, Angelica Beate Winter Boldt   +8 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Causal association of smoking and laryngeal cancer: A Mendelian randomization study. [PDF]

Tob Induc Dis
Yang F, Chen X, Wei R, Lv P, Alhoot MA.
europepmc   +1 more source

Do Obesity Classifications Create the Obesity Paradox? A Scoping Review of Obesity Definitions Applied in Sepsis Research

Clinical Obesity, EarlyView.
ABSTRACT Obesity appears to be associated with improved health outcomes in patients with sepsis, a phenomenon termed the obesity paradox. However, the potential influence of varying operational definitions of obesity on clinical outcomes within this paradox remains inadequately characterised.
Efris Kartikasari, Brian Robinson, Caz Hales   +2 more
wiley   +1 more source

Causal Relationship Between Galectins With Neuroblastoma: A Mendelian Randomization Study. [PDF]

Mol Neurobiol
Long C, Liang P, Liu X, Wang Y.
europepmc   +1 more source

Disentangling the relationship between glucose, insulin and brain health: A UK Biobank study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Background Glycaemic traits are associated with poorer brain health and dementia risk. Recent advances in genetic instruments for specific glycaemic markers enable an in‐depth investigation of the likely nature of associations and underlying mechanisms between diabetes‐related mechanisms and brain health and dementia.
Andrew C. Mason, Nasri Fatih, Reecha Sofat, Christopher T. Rentsch, Liam Smeeth, Krishnan Bhaskaran, Nish Chaturvedi, Victoria Garfield   +7 more
wiley   +1 more source

Blood urea nitrogen and bladder cancer: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Bai J, Wang L.
europepmc   +1 more source

Two-sample Mendelian randomisation:avoiding the downsides of a powerful, widely applicable but potentially fallible technique [PDF]

, 2016
Davey Smith, George, Davies, Neil, Hemani, Gibran, Pires Hartwig, Fernando   +3 more
core   +1 more source

Association Between Di‐(2‐Ethylhexyl) Phthalate and Childhood Asthma Through Plasma Metabolome Alterations

Allergy, EarlyView.
Mi Jeong Kim, Seung Hwa Lee, Su Jung Kim, Ha Eun Song, Hyoyeong Lee, Mi Jin Kang, Song‐I Yang, Hyo‐Bin Kim, So Yeon Lee, Jeong‐Hyun Kim, Hosub Im, Hoon Je Seong, Yong Joo Park, Jeonghun Yeom, Ji‐Hye Oh, Eom Ji Choi, Dong In Suh, Kyung Won Kim, Kangmo Ahn, Youn Ho Shin, Soo‐Jong Hong, Hyun Ju Yoo   +21 more
wiley   +1 more source

Implications of inflammation and sex in lower extremity arterial disease

European Journal of Clinical Investigation, EarlyView.
The graphical abstract illustrates the role of inflammation and sex‐related differences in lower extremity artery disease (LEAD). Key inflammatory biomarkers associated with LEAD include C‐reactive protein (CRP), fibrinogen, interleukin‐6 (IL‐6), and D‐dimer, which contribute to vascular inflammation and atherosclerotic plaque formation in lower limb ...
Katja Schnidrig, Manovriti Thakur, Aleksandra Tuleja, Sarah Maike Bernhard, Heidi Noels, Drosos Kotelis, Marc Schindewolf, Yvonne Döring   +7 more
wiley   +1 more source