Results 201 to 210 of about 1,141,533 (358)

Mendelian randomization analysis revealed causal effects from gut microbiota to abdominal obesity [PDF]

, 2020
Qian Xu, Shanshan Zhang, Yu‐Fang Pei, Jing‐Jing Ni, Lei Zhang, Ruirui Wang, Yu-Jing Weng, Xun Cui, Xin‐Tong Wei   +8 more
openalex   +1 more source

The bidirectional causal effects of brain morphology across the life course and risk of Alzheimers disease: A cross-cohort comparison and Mendelian randomization meta-analysis [PDF]

, 2021
Roxanna Korologou‐Linden, Bing Xu, Elizabeth Coulthard, Esther Walton, Alfie Wearn, Gibran Hemani, Tonya White, Charlotte A. M. Cecil, Tamsin Sharp, Henning Tiemeier, Tobias Banaschewski, Arun L.W. Bokde, Erin Burke Quinlan, Sylvane Desrivières, Herta Flor, Antoine Grigis, Penny Gowland, Andreas Heinz, Rüdiger Brühl, Jean‐Luc Martinot, Marie‐Laure Paillère Martinot, Éric Artiges, Frauke Nees, Dimitris Papadopoulos Orfanos, Tomáš Paus, Luise Poustka, Millenet Sabina, Juliane H. Fröhner, Lauren Robinson, Michael N. Smolka, Henrik Walter, Jeanne Winterer, Robert Whelan, Günter Schumann, Laura D Howe, Yoav Ben‐Shlomo, Neil M Davies, Emma L. Anderson   +37 more
openalex   +1 more source

Development of a prognostic nomogram and genetic insights for prostate cancer patients with secondary primary malignancies: A SEER retrospective cohort study and Mendelian randomization analysis

UroPrecision, EarlyView.
Abstract Background Prostate cancer (PCa) patients are at risk of developing second primary malignancies (SPMs), which can significantly shorten their survival. Understanding the risk of SPMs and associated factors is crucial to the optimization of patient follow‐up.
Qi Zhang, Lufan Liang, Ziyu Liu, Ziyang Yang, Jiahao Cheng, Xuan Li, Yueting Huang, Weisi Chen, Jiazhen Yin, Ligong Chen, Zhang Cao, Di Gu   +11 more
wiley   +1 more source

Testosterone and cardiovascular risk factors in men, a mendelian randomization analysis in the Guangzhou Biobank Cohort Study [PDF]

, 2013
J Zhao, TH Lam, Kar Keung Cheng, B Liu, Wangjingyi Zhang, C.Q. Jiang, GM Leung, C. Mary Schooling   +7 more
openalex  

Genetically Predicted Testosterone and Systemic Inflammation in Men: A Separate-Sample Mendelian Randomization Analysis in Older Chinese Men

, 2015
Jie Zhao, Chaoqiang Jiang, TH Lam, Bin Liu, Kar Keung Cheng, Lin Xu, Shiu Lun Au Yeung, Weisen Zhang, GM Leung, C. Mary Schooling   +9 more
openalex   +2 more sources

Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer’s dementia: a network Mendelian randomization analysis [PDF]

, 2021
Di Liu, Youxin Wang, Huiquan Jing, Qun Meng, Jingyun Yang   +4 more
openalex   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Plasma cytokine levels and PCOS risk: Mendelian randomization analysis reveals IL6R as a preventive factor

Journal of Ovarian Research
Background Polycystic ovary syndrome is a prevalent gynecological condition affecting primarily women of childbearing age. It is characterized by elevated androgen levels, ovulatory dysfunction, and morphological abnormalities. Despite extensive research
Xiaopei Li, Yan Li, Bumei Zhang, Jianmei Wang, Yang Yang, Yongrui Du   +5 more
doaj   +1 more source

Functional validation of a white pupae minimal gene construct in Ceratitis capitata (Diptera: Tephritidae)

Insect Science, EarlyView.
An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates, Roswitha A. Aumann, Inga Sievers, Tanja Rehling, Marc F. Schetelig   +4 more
wiley   +1 more source

Two-Sample Mendelian Randomization Analysis of Associations Between Periodontal Disease and Risk of Cancer [PDF]

, 2021
Laura Corlin, Mengyuan Ruan, Konstantinos K. Tsilidis, Emmanouil Bouras, Yau‐Hua Yu, Rachael Z. Stolzenberg‐Solomon, Alison P. Klein, Harvey A. Risch, Christopher I. Amos, Lori C. Sakoda, Pavel Vodička, Pai K Rish, James D. Beck, Elizabeth A. Platz, Dominique S. Michaud   +14 more
openalex   +1 more source