Results 181 to 190 of about 42,228 (267)

Causal associations between lifestyle factors and hemorrhoidal disease: Insights from Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Xiong J, Xu Y, Liu X, Liu C, Gao Q.
europepmc   +1 more source

Breeding 5.0: Artificial intelligence (AI)‐decoded germplasm for accelerated crop innovation

Journal of Integrative Plant Biology, EarlyView.
ABSTRACT Crop breeding technologies are vital for global food security. While traditional methods have improved yield, stress tolerance, and nutrition, rising challenges such as climate instability, land loss, and pest pressure now demand new solutions.
Jiayi Fu, Shouzhi Zheng, Longjiang Fan, Xiaoming Zheng, Qian Qian   +4 more
wiley   +1 more source

Blood cell traits on cardiovascular morpho-functional phenotypes: evidence from Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Li M, Zhu H, Shen L, Teng Y, Xiang X, Wei Y, Zhao K, Sun Z.   +7 more
europepmc   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Causality between noise pollution and Alzheimer disease: A Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Chen ZH, Wang LX, Li R, Jiang YH, Zong GH, Yi ZX, Ren XY, Jia BH.   +7 more
europepmc   +1 more source

A Principled Framework for Mendelian Randomization in Oral Health Research

Journal of Periodontal Research, EarlyView.
This methodological article provides a clear and accessible overview of Mendelian randomization for oral health researchers, emphasizing the core assumptions needed for credible causal inference. Focusing on applications in oral health, particularly periodontitis, it highlights both the strengths and limitations of the study design in order to support ...
Nasir Z. Bashir, Mario Romandini, Moritz Kebschull, Konstantinos K. Tsilidis, Dominique S. Michaud, Stephen Burgess   +5 more
wiley   +1 more source

Mendelian randomization analysis links HLA-DR+ CD14- CD16+ monocytes to CCL19-driven ankylosing spondylitis risk. [PDF]

Medicine (Baltimore)
Bei L, Liao J, Tan C, Li X, Yang Z.
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

The mechanism of gut microbiota in septic cardiomyopathy based on the bulk transcriptome and Mendelian randomization analysis. [PDF]

Front Immunol
Tao Y, Li L, Wang J, Du W, Ye S, Lu J.
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source