Results 171 to 180 of about 23,652,556 (316)

Positive results of Mendelian randomization analysis (after removing outliers by the MR-PRESSO test).

Positive results of Mendelian randomization analysis (after removing outliers by the MR-PRESSO test).
Liangliang Geng (18476051), Guannan Liu (642713), Tongyi Li (694610), Yunjiao Yang (4966963), Cong Long (13954245), Qiu Chen (4406077), Haichen Li (1883455)   +6 more
core   +1 more source

Dietary factors and risk for endometriosis: a Mendelian randomization analysis

Nutrition & Metabolism
Abstract Aims Observational studies have reported an association between dietary factors and endometriosis, but the causality remains unknown. The study aimed to evaluate the potential causal effect of dietary factors on endometriosis. Methods We performed a two-sample Mendelian randomization (MR) analysis to investigate the effects of 18 diet ...
Zhang, Xia, Zheng, Qiaomei, Chen, Lihong
openaire   +2 more sources

Decoding the Gut‐Brain Axis: Multi‐Omics Reveals a Causal Chain Linking Human Genome, Gut Microbiota, Blood Metabolites, and Alertness in the Brain

Med Research, EarlyView.
This multi‐omics study identified genetic loci, gut microbiota, blood metabolites, and gray matter volumes of orbitofrontal cortex and cerebellum that were potentially relevant to alerting in healthy Chinese adults. Subsequent two‐step one‐sample Mendelian randomization further revealed a serial mediation pathway: Bacteroides intestinalis influences ...
Hongru Li, Chuansheng Chen, Ofir Turel, Yu Pu, Hong Chen, Tingyong Feng, Jiang Qiu, Xu Lei, Qinghua He   +8 more
wiley   +1 more source

No Genetic Causal Relationship Between HIV Infection and Insulin Resistance, Diabetes: A Bidirectional Mendelian Randomization Analysis

Journal of Multidisciplinary Healthcare
Pengfei Liu,1 Qiurong Zeng2 1Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan, People’s Republic of China; 2Department of Laboratory Medicine, North Sichuan Medical College, Nanchong, Sichuan, People’s Republic of ...
Liu P, Zeng Q
doaj  

Association of Physical Activity with Asthma and Chronic Obstructive Pulmonary Disease and Mediation of Frailty: Mendelian Randomization Analyses

International Journal of COPD
Nanxin Chen,1 Xuejie Si,2 Jun Wang,2 Wenjing Chen2 1First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250014, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, The ...
Chen N, Si X, Wang J, Chen W
doaj  

Effects of fourteen essential minerals and vitamins on acute and chronic tubulointerstitial nephritis: a multivariate Mendelian randomization study

Hereditas
Objective To investigate the causal relationship between minerals and vitamins and acute and chronic tubulointerstitial nephritis by Mendelian randomization.
Xiaotan Pan, Zhiyan Guo, Yin Zheng, Cheng Su, Jiabo Chen   +4 more
doaj   +1 more source

Results of the Mendelian randomization analysis for emotional disorders and HRV (RMSSD).

Results of the Mendelian randomization analysis for emotional disorders and HRV (RMSSD).
Rui Wang (52434), Xu Luo (180879), YunXiang Zhou (18120934), Wen Xie (104834)   +3 more
core   +1 more source

Statin Exposure and Survival Outcomes in Amyotrophic Lateral Sclerosis in an Asian Cohort

Muscle &Nerve, EarlyView.
ABSTRACT Introduction Data from Asian cohorts on whether statin therapy affects amyotrophic lateral sclerosis (ALS) progression are limited. We examined whether statin exposure was associated with ALS disease duration or tracheostomy‐free survival in a multiethnic Asian ALS cohort.
Anushika Raheja, Kexin Ang, Bernett Lee, Seyed Ehsan Saffari, Eng King Tan, Crystal Jing Jing Yeo   +5 more
wiley   +1 more source

Results of Mendelian randomization analysis of iron status biomarkers on anxiety disorders.

Results of Mendelian randomization analysis of iron status biomarkers on anxiety disorders.
Guangzhen Fu (728487), Qiang Zhao (105948), Qi Gao (133189), Ruiying Yin (18272129)   +3 more
core   +1 more source

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source