Results 161 to 170 of about 42,228 (267)

Triglyceride-glucose index, plasma metabolome and aortic stenosis: a Mendelian randomization analysis. [PDF]

J Cardiothorac Surg
Yan Z, Wang Y, Dai X, Chang Q.
europepmc   +1 more source

Leisure‐Time Physical Activity on Age‐Modelled Trajectories of Body Mass Index and Obesity Risk Throughout Life: Multivariable Regression and Mendelian Randomization Analyses Using Electronic Health Record Data From the CORDELIA‐Catalunya Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To assess whether self‐reported leisure‐time physical activity, moderate‐to‐vigorous leisure‐time physical activity, and genetically determined cardiorespiratory fitness are associated with age‐related BMI trajectories and incident obesity. Methods We pooled 14 993 adults (30–90 years; 52.7% women; cohorts: REGICOR‐ACRISC, ILERVAS, ARTPER)
Javier Hernando‐Redondo, Anna Camps‐Vilaró, Roberto Elosua, Eleonora Fornara, Marcelino Bermúdez‐López, Pere Torán‐Monserrat, Ainara Jiménez‐Navarro, José M. Valdivielso, Víctor M. López‐Lifante, Tomàs Salas‐Fernández, Serafí Cambray, Raquel Cruz, Jaume Marrugat, Álvaro Hernáez   +13 more
wiley   +1 more source

Glycolysis-related genes for bladder cancer: A Mendelian randomization analysis. [PDF]

Biochem Biophys Rep
Hong X, Wang G, Hong T, Liu X, Lin S, Liu G, Lin W, Zhang Y.   +7 more
europepmc   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Identifying therapeutic target genes for stroke through systematic druggable Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Xia J, Zheng J, Zou S, Zhao H, Liu Q, Zhang R, Xu L.   +6 more
europepmc   +1 more source

The association between sarcopenia and cirrhosis: a Mendelian randomization analysis

Hepatobiliary Surgery and Nutrition, 2023
Ran, Shu, Yao, Jia, Liu, Baolin
openaire   +2 more sources

Estimation of Genetic Variance and Breeding Values for Infectious Disease Susceptibility From Simulated Longitudinal Data Using Generalized Linear Mixed Models Based on Transmission Dynamics

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Recent theoretical work shows that the potential of genetic selection to reduce the prevalence of infectious diseases is much larger than expected from classical quantitative genetic theory, due to indirect genetic effects that arise in the transmission process. However, to fully benefit from these indirect effects, we need to estimate genetic
A. D. Hulst, R. Pong‐Wong, A. Doeschl‐Wilson, M. C. M. De Jong, P. Bijma   +4 more
wiley   +1 more source

Investigating the causal role of immune cells in preeclampsia: Insights from Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Ma L, Yao L, Jiang M.
europepmc   +1 more source

Instrumental Variables Analysis and Mendelian Randomization for Causal Inference

The Journal of Infectious Diseases
Moodie, E.E.M., Cessie, S. le
openaire   +4 more sources

Population Differentiation and Polygenic Selection in the Finnish Ayrshire Cows Selected on Genomic Information

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The Finnish Ayrshire cattle belong to the Nordic Red breeds. The basis of selection in Nordic Red breeds shifted from traditional pedigree‐based breeding values to genomic breeding values between 2011 and 2014. Joint genetic evaluation and admixture among the Nordic Red breeds have led to the formation of a composite Nordic Red population ...
Katri Sarviaho, Minna Koivula, Terhi Iso‐Touru, Pekka Uimari, Katja Hänninen   +4 more
wiley   +1 more source