Results 161 to 170 of about 23,652,556 (316)

The selection of vitamin D SNPs for the use as instruments in Mendelian Randomization (MR) analysis.

, 2012
The selection of vitamin D SNPs for the use as instruments in Mendelian Randomization (MR) analysis.
Karani S. Vimaleswaran (149354), Elina Hyppönen (163747), Diane J. Berry (163739), John C. Whittaker (51412), Aroon D. Hingorani (142610)   +4 more
core   +1 more source

Circulating Omega‐3 Fatty Acids and Cardiometabolic Outcomes: A Systematic Review of Publications From UK Biobank

Lipids, EarlyView.
ABSTRACT Studies have shown that omega‐3 fatty acids may protect against cardiovascular diseases (CVDs) and related metabolic conditions. UK Biobank is a large cohort study that includes data on plasma omega‐3 fatty acids at study entry and health outcomes during the follow‐up period.
Warda Tul Firdous, Philip C. Calder
wiley   +1 more source

Mendelian randomization analysis of druggable gene expression in liver cancer risk and autoimmune hepatitis

Discover Oncology
Background Liver cancer remains one of the most prevalent and lethal malignancies worldwide, while autoimmune hepatitis is an immune-mediated inflammatory liver disease characterized by circulating autoantibodies and distinctive histopathological ...
Mingming Lian, Jun Yao
doaj   +1 more source

Results of the Mendelian randomization analysis for emotional disorders and HRV (SDNN).

Results of the Mendelian randomization analysis for emotional disorders and HRV (SDNN).
Rui Wang (52434), Xu Luo (180879), YunXiang Zhou (18120934), Wen Xie (104834)   +3 more
core   +1 more source

Causality between immunocytes and polymyositis: A Mendelian randomization analysis

Medicine
Polymyositis is a prominent subgroup of idiopathic inflammatory myopathy, considered to have an autoimmune etiology. However, research exploring the condition between immunocytes and polymyositis remains limited, indicating the need for further investigation to unravel these intricate associations. We employed bidirectional Mendelian randomization (MR)
Ni Yang, Chang Li, Ruhui Liu, Xianghua Qi, Xing Qian   +4 more
openaire   +2 more sources

The Role and Assessment of Lipid Profile in Patients With a Chronic Total Coronary Occlusion

Lipids, EarlyView.
This review summarized evidence on lipid profiles in CTO patients, non‐CTO patients, and healthy individuals, and examined the reported associations between lipid parameters, collateral channel formation, and clinical outcomes. Several key findings emerged from the present study.
Karol Sadowski, Dominika Tomkiel, Roel Hoek, Ruben W. de Winter, Nick S. Nurmohamed, Bimmer E. P. M. Claessen, Niels J. Verouden, Alexander Nap, Sebastiaan A. Kleijn, Mariusz Tomaniak, Yvemarie B. O. Somsen, Paul Knaapen   +11 more
wiley   +1 more source

Uncovering prognostic markers and therapeutic targets in acute myeloid leukemia: Insights from differential gene expression and Mendelian randomization analysis

Medicine in Omics
The development and prognosis of acute myeloid leukemia (AML) are influenced by multiple factors. This study utilized bioinformatics analysis to explore differentially expressed genes (DEGs) in acute myeloid leukemia (AML) and non-tumor tissues ...
Yaqi Huang, Xiao Zhu, Dongpei Li
doaj   +1 more source

Mendelian randomization analysis results for emotional disorders and HRV (pvRSA/HF).

Mendelian randomization analysis results for emotional disorders and HRV (pvRSA/HF).
Rui Wang (52434), Xu Luo (180879), YunXiang Zhou (18120934), Wen Xie (104834)   +3 more
core   +1 more source

Advancing Artificial Intelligence in Myopia Management: From Predicting Progression to Supporting Clinical Decisions

Med Research, EarlyView.
The AI‐enabled multimodal framework for whole‐life myopia management. Graphical abstract illustrates the transition of myopia care from premyopia to myopia, high myopia, and pathologic myopia. Multimodal data, including demographic and refractive information, genetic, behavioral and environmental factors, ophthalmic imaging, and omics profiles, can be ...
Zewei Zhang, Yun Wang, Lifei Zhang, Dongmei Chen, Weijie Zhang, Fang Li, Jibo Zhou   +6 more
wiley   +1 more source

Association between a history of hypothyroidism and incident chronic kidney disease and potential mediators: A cohort study with Mendelian randomization analysis

Journal of International Medical Research
Objective To investigate the association between hypothyroidism and incident chronic kidney disease and identify potential mediators. Methods This study included a retrospective cohort and Mendelian randomization analysis.
Yaofang Zhang, Yue Shen, Aiwen Shen, Yuqi Shen, Zhu Zhu, Yining He, Wenji Wang, Xuezhu Li, Xiao Bi, Feng Ding   +9 more
doaj   +1 more source