Mendelian randomization analysis of gut microbiota-immune cell interactions in malignant neoplasm of nasopharynx. [PDF]
Chen Q+11 more
europepmc +1 more source
Impact of particulate matter exposure on melanoma risk: A multicentre case–control study
Long‐term exposure to higher levels of PM10 and PM2.5 may have a protective effect against melanoma, potentially due to the reduction in ultraviolet radiation. Abstract Background The relationship between particulate matter (PM) exposure and melanoma risk remains largely unexplored.
Francesco Bellinato+8 more
wiley +1 more source
Causality between ischemic stroke and glioblastoma: Bidirectional Mendelian randomization analysis. [PDF]
Liu HC, Yang YJ, Wei ZH, Liu N.
europepmc +1 more source
Helicobacter pylori Infection and Eradication in Relation to Gastroesophageal Reflux Disease
ABSTRACT Background and Aim The effect of Helicobacter pylori (H. pylori) infection and eradication on the risk of gastroesophageal reflux disease (GERD) is still unclear. Methods We conducted a systematic review with a comprehensive literature search in the bibliographic databases Embase, Medline, and Cochrane Library through May 2024.
Hejie Wang+8 more
wiley +1 more source
Immune Cell Proteins and Parkinson's Disease: A Mendelian Randomization Analysis of Causal Associations. [PDF]
Li H+7 more
europepmc +1 more source
Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah+8 more
wiley +1 more source
Genetically proxied inhibition of Phosphodiesterase-5 and cancer risks: A drug-target Mendelian randomization analysis. [PDF]
Tang K, Li B, Wu X, Wang M.
europepmc +1 more source
Abstract Background Type 1 diabetes (T1D) increases premature mortality risk, with cardiovascular disease being the leading cause. Chronic inflammation may play a role. Associations between inflammatory biomarkers and mortality are not well‐known in T1D.
Hashmat Sayed Zohori Bahrami+7 more
wiley +1 more source
Exploring potential therapeutic targets for cardiomyopathy: A proteome-wide Mendelian randomization analysis. [PDF]
Ji Y+6 more
europepmc +1 more source
Abstract Objective Examine the association between adolescent cardiorespiratory fitness and future risk of depression and dispensation of antidepressants, including the role of familial confounding. Methods A cohort study with sibling‐comparisons based on Swedish men who participated in mandatory military conscription examinations from 1972 to 1995 ...
Marcel Ballin+4 more
wiley +1 more source