Results 261 to 270 of about 23,652,556 (316)

The Role of Integrin Family in Atherosclerotic Cardiovascular Disease: A Prospective Cohort Study and Mendelian Randomization Analysis. [PDF]

Biomedicines
Niu M, Feng Y, Shu K, Yang Y, Chen J, Lai Z, Liu B, Peng B.   +7 more
europepmc   +1 more source

Elevated Blood Pressure Is Causally Associated With Larger Subcortical Gray Matter Structure Through Perivascular Clearance Routes

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Background This study aimed to investigate the association between elevated blood pressure (BP) and subcortical gray matter structures, and to elucidate the causality and underlying mechanisms. Methods This study enrolled 1012 participants from a multicenter, population‐based cohort study in China.
Jing Sun, Jing Li, Xiaoshuai Li, Xinyu Zhao, Pengfei Zhao, Zhenghan Yang, Shuohua Chen, Shouling Wu, Ying Hui, Zhenchang Wang, Han Lv   +10 more
wiley   +1 more source

Leisure screen time, cardiometabolic pathways, and frailty: A two-step Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Cao Y, Fan Q, Xia N, Hao Q, Feng Y.
europepmc   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Exploring the Causal Relationship Between Sex Hormones and Depression by Means of Two-Sample Mendelian Randomization Analysis. [PDF]

Actas Esp Psiquiatr
Gao H, Du X, Huo Y, Pan H, Xu Y, Hou Y.
europepmc   +1 more source

Beyond the Management Gene: Rethinking and Advancing the Genetic Perspective in Management

Journal of Management Studies, EarlyView.
Abstract Genetics has emerged as a promising avenue for explaining differences in management outcomes, attracting attention from leadership, entrepreneurship, and organizational behaviour scholars. Nonetheless, the field has faced scepticism and made only limited progress, stagnating in the pursuit of a so‐called ‘management gene’ (e.g., leadership ...
Ahmed Maged Nofal, Marcus Wolfe
wiley   +1 more source

Does Toxoplasma gondii infection have a causal impact on human psychopathology? A Mendelian randomization analysis. [PDF]

PLoS Pathog
Pang J, Valente MJ, Kim K, Liu X.
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Immune cells and ischemic stroke: A bidirectional Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Wang N, Guo W, Xie Y, Gong Y, Tao H.
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source