Results 121 to 130 of about 8,481 (189)

Deep brain lymphatic vessels: a new player in brain functions, neurodegenerative diseases and psychiatric disorders

open access: yesStress and Brain
The brain was previously believed to be an “immune privileged” organ without an immune system. However, recent discoveries have shown a connection between the peripheral lymphatic system and the brain.
Bingqing Guo   +2 more
doaj   +1 more source

Meningeal lymphatic supporting cells govern the formation and maintenance of zebrafish mural lymphatic endothelial cells

open access: yesNature Communications
The meninges are critical for the brain functions, but the diversity of meningeal cell types and intercellular interactions have yet to be thoroughly examined. Here we identify a population of meningeal lymphatic supporting cells (mLSCs) in the zebrafish
Xiang He   +4 more
doaj   +1 more source

Cerebrospinal fluid dynamics between the intracranial and the subarachnoid space of the optic nerve. Is it always bidirectional? [PDF]

open access: yes, 2017
CSF is thought to flow continuously from the site of production in the ventricles into interconnected spaces; i.e. cisterns and subarachnoid spaces (SASs).
Flammer, J.   +5 more
core  

Bone Marrow Derived Myeloid Cells Regulate Meningeal Lymphatic Vessel Development

open access: yes
Meningeal lymphatic vessels (mLVs) in the dura mater drain cerebrospinal fluid and toxic brain waste out of the central nervous system to maintain brain health. mLVs develop postnatally, and macrophages are associated with developing mLVs. Since monocytes replenish dural macrophages, we hypothesized that monocytes differentiate into macrophages to ...
openaire   +1 more source

Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer’s disease-related amyloid pathology

open access: yesNature Cardiovascular Research
AbstractDiscovery of meningeal lymphatic vessels (LVs) in the dura mater, also known as dural LVs (dLVs) that depend on vascular endothelial growth factor C expression, has raised interest in their possible involvement in Alzheimer’s disease (AD). Here we find that in the APdE9 and 5xFAD mouse models of AD, dural amyloid-β (Aβ) is confined to blood ...
Salli Antila   +26 more
openaire   +3 more sources

The Ins and Outs of B Cells in Multiple Sclerosis [PDF]

open access: yes, 2015
Gregory P. Owens   +2 more
core   +1 more source

Ultrasmall inorganic nanoparticles repair damaged meningeal lymphatic vessels to boost Parkinson’s disease therapy

open access: yesProceedings of the National Academy of Sciences
Meningeal lymphatic vessels (MLVs) have been identified to associate with various neurological diseases, such as traumatic brain injury (TBI), Alzheimer’s disease (AD), Parkinson’s disease, multiple sclerosis, and brain tumors. Damage to MLVs can exacerbate the pathological progression of these diseases and significantly impede therapeutic
Mengxiao Han   +7 more
openaire   +1 more source

Influence of meningeal lymphatic vessels on brain mechanisms

open access: yesProceedings for Annual Meeting of The Japanese Pharmacological Society, 2019
Masashi Matsuoka   +3 more
openaire   +2 more sources

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