Results 121 to 130 of about 6,015 (163)

The role and mechanism of Aβ clearance dysfunction in the glymphatic system in Alzheimer's disease comorbidity. [PDF]

Front Neurol
Li H, Yao Q, Huang X, Yang X, Yu C.
europepmc   +1 more source

Skull bone marrow and skull meninges channels: redefining the landscape of central nervous system immune surveillance. [PDF]

Cell Death Dis
Liu L, Zhang X, Chai Y, Zhang J, Deng Q, Chen X.   +5 more
europepmc   +1 more source

Border-associated macrophages as gatekeepers of brain homeostasis and immunity.

Immunity
Vara-Pérez M, Movahedi K.
europepmc   +1 more source

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Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid

Nature, 2019
Recent work has shown that meningeal lymphatic vessels (mLVs), mainly in the dorsal part of the skull, are involved in the clearance of cerebrospinal fluid (CSF), but the precise route of CSF drainage is still unknown. Here we reveal the importance of mLVs in the basal part of the skull for this process by visualizing their distinct anatomical location
Gou Young Koh, Z A Meadows, Sang Heon Suh   +2 more
exaly   +4 more sources

Barenblatt-like approach to transport processes in meningeal lymphatic vessel’s dynamics

The European Physical Journal Plus, 2021
We propose a model, which describes the transfer of a marker inside the lymphatic microvessel by the lymph flow as a consequence of the vessel’s elastic deformation, which produces the pushing pressure jump. The resulting model is close to the equation of the nonlinear diffusion with a localized moving front solution.
Anastasia I. Lavrova, Eugene B. Postnikov   +1 more
openaire   +2 more sources

Impairment of the Glymphatic Pathway and Putative Meningeal Lymphatic Vessels in the Aging Human

Annals of Neurology, 2020
ObjectiveAging is a major risk factor for numerous neurological disorders, and the mechanisms underlying brain aging remain elusive. Recent animal studies demonstrated a tight relationship between impairment of the glymphatic pathway, meningeal lymphatic vessels, and aging.
Ying Zhou, Jinsong Cai, Wenhua Zhang, Xiaoxian Gong, Shenqiang Yan, Kemeng Zhang, Zhongyu Luo, Jianzhong Sun, Quan Jiang, Min Lou   +9 more
openaire   +3 more sources

Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system

Nature Neuroscience, 2022
Recent studies have demonstrated that brain meningeal lymphatic vessels (MLVs) act as a drainage path directly into the cervical lymph nodes (CLNs) for macromolecules contained in the cerebrospinal fluid (CSF). However, the role of MLVs during CNS viral infection remains unexplored. Here, we found that infection with several neurotropic viruses in mice
Xiaojing Li, Linlin Qi, Dan Yang, ShuJie Hao, Fang Zhang, Xingguo Zhu, Yue Sun, Chen Chen, Jing Ye, Jing Yang, Ling Zhao, Daniel M. Altmann, Shengbo Cao, Hongyan Wang, Bin Wei   +14 more
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Complexity Analysis and u-net Based Segmentation of Meningeal Lymphatic Vessels

2020 54th Asilomar Conference on Signals, Systems, and Computers, 2020
This paper showcases a u-net based architecture for the automated segmentation images of meningeal lymphatic vessels. These lymphatic vessels surround the cerebral cortex and have been recently found to drain waste from the brain. Studies on mice have shown loss of memory and impairment in cognitive ability if the vessels’ draining capacity does not ...
Jasmin Herz, Nazia Tabassum, Scott T. Acton, Michael Ferguson   +3 more
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Continuous theta burst stimulation dilates meningeal lymphatic vessels by up-regulating VEGF-C in meninges

Neuroscience Letters, 2020
Lymphatic vessels (LVs) of meninges and lymphatic drainage in the brain have been investigated previously. Here, we examined the role of continuous theta burst stimulation (CTBS) in the modulation of meningeal LVs.To explore the effects of CTBS on meningeal LVs, the diameters of LVs were measured between a real CTBS group and sham CTBS group of wild ...
Zhong Pei, Cheng Wu, Guang-qing Xu, Ying-hua Jing, Meng-Ni Li, Yue Lan, Yue Lan, Hui-Xian Yu, Ge Li, Fengyin Liang, Xue Li, Pei Dai   +11 more
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Impaired meningeal lymphatic vessels exacerbate early brain injury after experimental subarachnoid hemorrhage

Brain Research, 2021
Blood that enters the subarachnoid space (SAS) and its breakdown products are neurotoxic and are the principal inducers of brain injury after subarachnoid hemorrhage (SAH). Recently, meningeal lymphatic vessels (MLVs) have been proven to play an important role in clearing erythrocytes that arise from SAH, as well as other macromolecular solutes ...
Yan Zhao, Bangyue Wang, Jian Li, Weihan Wang, Hao Zhang, Xinyu Yang, Xinyu Yang, Changkai Hou, Quanlei Liu, Cong Fu   +9 more
openaire   +3 more sources