Results 121 to 130 of about 36,804 (221)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang, Shucheng Jin, Penghui Guo, Yuying Yin, Yichun Hua, Xiaosheng Ding, Zhe Zhang, Shuo Chen, Xu Han, Baowang Li, Yan Liu, Xiaoyan Li, Deling Li, Jing Jing, Wei Shi, Wang Jia   +15 more
wiley   +1 more source

Peripheral accumulation of newly produced T and B lymphocytes in natalizumab-treated multiple sclerosis patients [PDF]

, 2012
The anti-α4 monoclonal antibody natalizumab inhibits lymphocyte extravasation into the central nervous system and increases peripheral T and B lymphocytes in multiple sclerosis patients.
Alessandra Sottini, Bielekova, Cinzia Zanotti, Crowley, del Pilar Martin, Emirena Garrafa, Fabio Torri, Federico Serana, Fletcher, Gorelik, Hug, Ifergan, Kivisäkk, Kogan, Krumbholz, Laplaud, Lee, Luigi Caimi, Luisa Imberti, Lutterotti, Marco Chiarini, Muraro, Niino, Pittet, Planas, Polman, Putzki, Ruggero Capra, Ryan, Sarah Rasia, Sawada, Schwab, Serana, Skarica, Sottini, Sottini, Stüve, Takada, van Zelm, Wipfler, Ye, Zanotti, Zohren   +42 more
core   +1 more source

Cerebrospinal fluid dynamics between the intracranial and the subarachnoid space of the optic nerve. Is it always bidirectional? [PDF]

, 2017
CSF is thought to flow continuously from the site of production in the ventricles into interconnected spaces; i.e. cisterns and subarachnoid spaces (SASs).
Flammer, J., Huber, A. R., Jaggi, G. P., Killer, H. E., Miller, N. R., Mironov, A.   +5 more
core  

Iron accumulates in the primate choroid of the eye with aging as revealed with synchrotron X-ray fluorescence microscopy [PDF]

, 2016
Aging leads to an increase in iron-loaded cellular structures in the choroid of the eye. This study was carried out to determine the distribution and content of iron, zinc and copper in the macular retina, choroid and retrobulbar optic nerve of young (4 ...
Geraki, K, Jeffery, G, Ugarte, M
core   +1 more source

Analysis of norepinephrine-regulated cerebral lymphatic drainage by the second near-infrared region in vivo imaging

APL Photonics
The cerebral lymphatic drainage plays an important role in the occurrence and development of central nervous system diseases. Recent studies have shown that cerebral lymphatic drainage is regulated by circadian rhythm and anesthesia state; however, the ...
Xi Li, Tianhao Yang, Zhongyang Zhang, Shengnan Wu, Zhen Yuan, Feifan Zhou   +5 more
doaj   +1 more source

Central nervous system lymphatic unit, immunity, and epilepsy : Is there a link? [PDF]

, 2019
Summary The recent definition of a network of lymphatic vessels in the meninges surrounding the brain and the spinal cord has advanced our knowledge on the functional anatomy of fluid movement within the central nervous system (CNS).
Abbott, Abbott, Abbott, Absinta, Al Nimer, Ali, Alitalo, Amor, Andrian, Antila, Aspelund, Bar-Klein, Barker, Bauer, Bauer, Betterman, Bhowmik, Bien, Brinker, Brouillard, Carare, Carare, Cserr, Daneman, Decker, Engel, Engelhardt, Frigerio, Galea, Gendelman, Giannoni, Granata, Guo, Haraldsen, Harling-Berg, Hawkins, Hladky, Hladky, Huggenberger, Iliff, Irani, Jones, Kandratavicius, Karaman, Kataru, Kerchner, Kesler, Kida, Kim, Klement, Kuo, Lancaster, Lei, Li, Liang, Liu, Lonser, Louveau, Louveau, Louveau, Maggio, Makinen, Marchi, Marchi, Marchi, Marchi, Marchi, Mendes, Molteni, Monti, Omalu, Omalu, Pardo, Perry, Plog, Podgrabinska, Puvenna, Rasmussen, Roberson, Robitaille, Saletti, Sarnat, Scheffer, Schwab, Sen, Shirai, Shultz, Sotiropoulos, Stamatovic, Szentistvanyi, Szuba, Tammela, Thom, Thomas, Tomkins, Tomkins, Urra, Varadkar, Vazana, Vezzani, Vincent, Visuri, Vos, Walsh, Walsh, Weller, Widner, Wilson, Zheng   +108 more
core   +3 more sources

dab2 is required for the scavenging function of lymphatic endothelial cells in the zebrafish meninges

Scientific Reports
To date it is only partially understood how the brain is cleared of waste products resulting from its high metabolic activity, although this process has important implications for the development and progression of neurodegenerative diseases.
Katharina Uphoff, Irina Suárez, Andreas van Impel, Stefan Schulte-Merker   +3 more
doaj   +1 more source

Dural Macrophages in The Regulation of Meningeal Lymphatic Vessel Structure and Brain Lymph Drainage

, 2023
Meningeal lymphatic vessels (mLVs) are the primary route for cerebrospinal fluid (CSF) outflow from the brain. Importantly, dysfunction of mLVs in mice has been shown to increase toxic protein accumulation, resulting in a decline in neurocognitive processing.
openaire   +2 more sources