Results 121 to 130 of about 327,511 (299)

Acquired narcolepsy secondary to a presumptive hypothalamic hamartoma in a young German wirehaired pointer dog

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 3‐year‐old, male, entire, German wirehaired pointer dog was presented with a 2‐year history of paroxysmal episodes of collapse associated with reduced levels of consciousness. A magnetic resonance imaging study identified a single, ill‐defined, non‐contrast‐enhancing, intra‐axial mass lesion involving the hypothalamus.
Callum Atkins   +3 more
wiley   +1 more source

Suspected calcitriol‐mediated hypercalcaemia and postmortem diagnosis of histiocytic sarcoma in a dog

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract This report describes a case of refractory ionised hypercalcaemia, of 12 months duration, in an 11‐year‐old, male, neutered beagle diagnosed with metastatic histiocytic sarcoma at postmortem examination. In this case, the parathyroid hormone levels were at the lower end of the reference interval, the parathyroid hormone‐related peptide was ...
Kerry E. Rolph   +5 more
wiley   +1 more source

Cauda equina tumor surgery: how I do it [PDF]

open access: yes, 2018
Background: Tumors of the cauda equina usually require surgery due to their impingement on neighboring nerve roots, often resulting in pain and neurological deficits. Method: The Authors first give a brief introduction on cauda equina tumors, followed by
Boex, Colette   +3 more
core  

The Current Situation and Development of Endoscopic Ear Surgery in China

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Endoscopic ear surgery has been widely performed in China since 2015 due to the development and rapid popularization of endoscopic technology. Due to the relative shortness of the auditory meatus, only a fixed endoscope is required in many cases, rather than a motion similar to a nasal endoscope, and uncontrollable bleeding is virtually non ...
Meng‐Wen Shi, Ge Yin, Yu Sun
wiley   +1 more source

Tuberculous meningitis causing holocord longitudinally extensive transverse myelitis

open access: yesSaudi Journal for Health Sciences
Longitudinally extensive transverse myelitis (LETM) is a neurological entity with characteristic inflammatory lesions in ≥3 vertebral segments of the spinal cord. It is most commonly associated with neuromyelitis optica spectrum disorder.
Nishanth Dev   +3 more
doaj   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post   +4 more
wiley   +1 more source

Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis

open access: yesBrain Pathology, EarlyView.
This study shows that components of the ESCRT‐III membrane repair machinery, VPS4B and CHMP2A, are dysregulated in progressive MS and are associated with higher neurodegeneration and inflammation. This might lead to improper function of the complex to inhibit the final stages of necroptosis activation and thus impede neuronal cell death.
Carmen Picon   +5 more
wiley   +1 more source

Pharmacological evaluation of non‐nucleotide purine derivatives as P2X7 antagonists for the treatment of neuroinflammation in traumatic brain injury

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and purpose Traumatic brain injury (TBI) is considered to be a leading cause of mortality and disability worldwide. After TBI, innate immunity is rapidly activated in response to damage‐associated molecular patterns, such as ATP release, recognised by P2X7 receptors.
Inés Valencia   +15 more
wiley   +1 more source

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

open access: yesCell Proliferation, EarlyView.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin   +6 more
wiley   +1 more source

Brain and Meningeal Metastases of Lung Cancer Manifested as Brain Calcifications: 
A Case Report and Literature Review

open access: yesChinese Journal of Lung Cancer
Lung cancer is still one of the most common malignant tumors in the world. With the increase of its incidence and the development of medical technology, the overall survival of lung cancer patients has significantly extended compared to before.
Deng ZHANG   +3 more
doaj   +1 more source

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