Results 61 to 70 of about 463,847 (234)

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, Volume 12, Issue 21, June 5, 2025.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source

Analysis of influencing factors of dismal prognosis in severe tuberculous meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Objective To investigate the influencing factors related to long ⁃ term prognosis in patients with severe tuberculous meningitis (TBM). Methods One hundred sixty⁃three patients with severe TBM admitted to Tianjin Haihe Hospital from June 2012 to December
LIU Chen⁃chao, LIU Hui⁃quan, YUAN Xiao⁃yong, WANG Jian, CHEN Shen, WANG Yi⁃yi, LIU Xing⁃jun   +6 more
doaj   +1 more source

Aspectos epidemiológicos da meningite tuberculosa em menores de 15 anos de idade, na Grande São Paulo, Brasil, 1982 -1983 Epidemiological aspects of tuberculous meningits in children under 15 years of age, Greater S. Paulo, Brazil, 1982 -1983

Revista de Saúde Pública, 1989
Foram estudadas algumas características epidemiológicas dos casos de meningite tuberculosa ocorridos em menores de 15 anos na Grande São Paulo (Brasil), nos anos de 1982 e 1983.
Stella M.C. Nardy, Roberto Brólio, Marília Belluomini   +2 more
doaj   +1 more source

Tuberculous meningitis of severe expression in pediatrics

Revista de la Facultad de Medicina Humana, 2020
Tuberculosis (TB) remains a major public health problem worldwide. The actual magnitude of this epidemic is underestimated due to difficulties in diagnosis in children and the limited reporting of this disease.
Guiliana Reyes Florián, Martin Seminario-Aliaga   +1 more
doaj   +1 more source

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, Volume 3, Issue 2, Page 148-157, June 2025.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Multiple intestinal perforations as a primary manifestation of abdominal tuberculosis in a HIV-infected patient

Journal of Surgical Case Reports, 2010
Abdominal tuberculosis (TB) is the sixth commonest extra-pulmonary TB form after lymphatic, genitourinary, bone and joint, miliary and meningeal tuberculosis.
Amir Hossein Sarrami, Mohsen Sharifi, Majid Ahsan, Noushin Afsharmoghaddam   +3 more
doaj  

Chinese Expert Consensus on Leptomeningeal Metastases of Lung Cancer

Thoracic Cancer, Volume 16, Issue 11, June 2025.
This Chinese expert consensus addresses leptomeningeal metastases (LM) in lung cancer, emphasizing early MRI‐enhanced imaging and CSF cytology for diagnosis. It recommends stratified management using LM‐molGPA and targeted therapies (e.g., third‐generation EGFR‐TKIs).
Gen Lin, Yongsheng Wang, Tao Xin, Ding Zhang, Qiuyu Zhang, Yangsi Li, Yudan Chi, Yun Fan, Anwen Liu, Haipeng Xu, Liang Shi, Longfeng Zhang, Qian Miao, Xiaobin Zheng, Lijun Li, Kaijia Zhou, Qiwei Yao, Zihua Zou, Kang Miao, Yaping Hong   +19 more
wiley   +1 more source

Autoantibodies Against Collapsin Response Mediator Proteins Associated With Encephalopathy/Myelopathy: A Single‐Center Retrospective Study

CNS Neuroscience &Therapeutics, Volume 31, Issue 6, June 2025.
This is a study to assess autoantibodies against CRMPs in a cohort of 400 patients with encephalopathy/myelopathy by CBA and TBA tests. Anti‐CRMPs Abs may indicate immune‐mediated neuronal damage in encephalopathy/myelopathy. ABSTRACT Background Collapsin response mediator protein (CRMP) consists of five subtypes (CRMP1–5), which share high homology ...
Dongmei Wang, Qiqi Wang, Sanming Jie, Guanghui Liu, Xiaozhen Huang, Yue Pan, Kaibiao Xu, Chujun Chen, Yihua Huang, Yawei Jiang, Zirui Chen, Weiling Deng, Fenfen He, Chaowei Dai, Suyue Pan, Yongming Wu, Yafang Hu   +16 more
wiley   +1 more source

Atypical Cerebral Manifestations of Disseminated Mycobacterium tuberculosis

Frontiers in Neurology, 2017
BackgroundWe investigated the patterns of cerebral manifestations in patients with underlying pulmonary or extrapulmonary tuberculosis or disseminated tuberculosis.Materials and methodsFrom January 2010 to September 2016, brain magnetic resonance imaging
Ji Hye Hwang, Kyung Mi Lee, Ji Eun Park, Hyug-Gi Kim, Eui Jong Kim, Woo Suk Choi, Na Rae Yang   +6 more
doaj   +1 more source

A rare case of tuberculous meningitis with pancreatitis

Medical Journal of Dr. D.Y. Patil University, 2016
Tuberculous meningitis (TBM) is the most common form of central nervous system manifestation of tuberculosis. However, tuberculous pancreatitis is rarely reported. We present an 8-year-old female child with TBM who had intractable vomiting that persisted
Drishti Chandru Tolani, Ira Shah
doaj   +1 more source