Results 61 to 70 of about 463,498 (239)
Tuberculosis Meningitis, still Misunderstood
Journal of Neuroinfectious Diseases, 2015 World Health Organization (WHO) estimates 9 millions of people developed tuberculosis in 2013, and 1.5 million died, including 360 000 people who were infected with human immunodeficiency virus (HIV) . 133 years after Robert Koch discovered the bacillus that cause the disease, tuberculosis remains a major global health problem. Tuberculosis meningitis (
Yanelis Pernas Sánchez +1 more
openaire +2 more sources
Heterogeneity of Innate Immunity
Organ Medicine, EarlyView.In the present review, we introduce the novel concept of categorizing innate immune responses according to the influence of the distinct cytokines that they release on adaptive immune cell differentiation. This framework underscores the interconnected and complex nature of immune responses, offering a fresh outlook for comprehensively understanding ...
Xiaohan Yu, Cheng Yang
wiley +1 more source
Neurosarcoidose: orientações para o neurologista geral [PDF]
, 2012 Neurosarcoidosis (NS) more commonly occurs in the setting of systemic disease. The diagnosis is based on a clinical history suggestive of NS, presence of noncaseating granulomas, and supportive evidence of sarcoid pathology, laboratory, and imaging ...
Abrahão, Agessandro +5 more
core +2 more sources
Glia, Volume 73, Issue 10, Page 1928-1950, October 2025.Main Points Multiple sclerosis involves chronic CNS inflammation and neurodegeneration. This review highlights glial cells as key drivers in progressive MS, focusing on lesion pathology, molecular dysfunction, and human‐relevant model systems. ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by ...
Volker Siffrin
wiley +1 more source
Hydrocephalus Caused by Tuberculous Meningitis in an Immunocompetent Young Adult: A Case Report
International Medical Case Reports Journal, 2023 Rizaldy Taslim Pinzon,1,2 Vanessa Veronica1 1Faculty of Medicine, Duta Wacana Christian University, Yogyakarta, Indonesia; 2Department of Neurology, Bethesda Hospital, Yogyakarta, IndonesiaCorrespondence: Rizaldy Taslim Pinzon, Duta Wacana Christian ...
Pinzon RT, Veronica V
doaj
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Advanced Science, Volume 12, Issue 34, September 11, 2025.Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu +17 more
wiley +1 more source
Incidence of tuberculous meningitis in the State of Santa Catarina, Brazil
Revista da Sociedade Brasileira de Medicina Tropical, 2014 Introduction The aim of this study was to estimate the incidence of tuberculous meningitis in the State of Santa Catarina (SC), Brazil, during the period from 2001 to 2010.
Cíntia Helena de Souza +6 more
doaj +1 more source
Recurrent Heerfordt-Waldenström Syndrome with thyroid and meningeal involvement in a Chinese woman
Respiratory Medicine Case Reports, 2023 Sarcoidosis is a multisystem granulomatous disorder of unknown etiology, manifesting with bilateral hilar adenopathy, pulmonary reticular opacities, skin, joint or eye lesions.
Joseph J. Zhao +4 more
doaj +1 more source
Cerebral Venous Thrombosis:Current Status and Challenges
Brain and Behavior, Volume 15, Issue 9, September 2025.Our review introduces treatment strategies for short‐term, long‐term, and permanent CVT risk factors, focusing on anticoagulant selection and treatment duration. We also discuss the current status of endovascular therapy for CVT, noting that it remains a challenge due to limited evidence, and more research is needed to optimize this approach.
Wenbo Zuo +5 more
wiley +1 more source
Neuroradiological manifestations of tuberculous meningitis [PDF]
, 2014 Tuberculous meningitis (TBM) represents the most severe form of extra pulmonarytuberculosis (1).The early and exact diagnosis of TBM is important but difficult due to time consuming definitive microbiological procedures (2).Neuroimaging is an important ...
Badshah, Mazhar +3 more
core +1 more source