The polo-like kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia [PDF]
CD56 is expressed in 15–20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis.
A Blair+55 more
core +12 more sources
Appearance of the canine meninges in subtraction magnetic resonance images [PDF]
The canine meninges are not visible as discrete structures in noncontrast magnetic resonance (MR) images, and are incompletely visualized in T1‐weighted, postgadolinium images, reportedly appearing as short, thin curvilinear segments with minimal ...
Frean, S P+3 more
core +1 more source
The development and origins of vertebrate meninges [PDF]
Meninges comprise three distinct layers, the dura mater, arachnoid, and pia mater that surround the brain, spinal cord and some parts of the nerves.
Batarfi, Munirah+4 more
core +1 more source
Pathomorphosis of Extrapulmonary Tuberculosis in Children [PDF]
Aim. To study clinical and epidemiological aspects of pathomorphosis of extrapulmonary tuberculosis clinical forms.Materials and Methods. Retrospective analysis of 138 case histories in children aged to 15 years, obtaining extrapulmonary tuberculosis ...
Mykolyshyn, L. (Lidia)+1 more
core +2 more sources
Tertiary lymphoid organs in central nervous system autoimmunity [PDF]
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
core +1 more source
Isolation, characterization, and substrate properties of the external limiting membrane from the avian embryonic optic tectum [PDF]
The external limiting membrane of the avian embryonic optic tectum is isolated by mechanically separating the neuronal mesencephalon from the overlying mesenchymal tissue.
Adler+58 more
core +1 more source
Effect of delayed acquisition times on Gadolinium-enhanced MRI of the presumably normal canine brain [PDF]
A delay in imaging following intravenous contrast medium administration has been recommended to reduce misdiagnoses. However, the normal variation of contrast enhancement in dogs following a delay has not been characterized.
Brannan, N.+5 more
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Brain tumors induced in rats by human adenovirus type 12 [PDF]
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu strains were injected intracranially with human adenovirus type 12. The incidence of intracranial tumors was 91% (30/33) in
Matsuo, Keisuke+5 more
core +1 more source
Imaging diagnosis: magnetic resonance imaging of diffuse leptomeningeal oligodendrogliomatosis in a dog with "dural tail sign" [PDF]
A case of diffuse leptomeningeal oligodendrogliomatosis affecting the brain and spinal cord of a dog is presented. A 7.5-year old, male neutered Staffordshire bull terrier presented for evaluation of a chronic history of tetraparesis and seizures, with a
Anwer+31 more
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Intracranial solitary fibrous tumor [PDF]
Solitary fibrous tumours are rare mesenchymal spindle-cell tumours that occur most often in the visceral pleura or liver. If they occur intracranially, they are extra-axially located and develop from the meninges.
Ceuppens, Jeroen+4 more
core +2 more sources