A Closer Look at the Global Management of Spina Bifida: The Implementation of Endoscopic Third Ventriculostomy in the Treatment of Spina Bifida-Related Hydrocephalus in Africa [PDF]
Spina bifida, specifically myelomeningocele, is a debilitating neural tube defect that affects patients and families throughout the world. Traditional management and treatment methods are described, followed by an explanation of why this is often ...
Burckart, Caryssa
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Nociceptive neuropeptide increases and periorbital allodynia in a model of traumatic brain injury. [PDF]
OBJECTIVE: This study tests the hypothesis that injury to the somatosensory cortex is associated with periorbital allodynia and increases in nociceptive neuropeptides in the brainstem in a mouse model of controlled cortical impact (CCI) injury.
Amenta, Peter S.+4 more
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Soft Null Hypotheses: A Case Study of Image Enhancement Detection in Brain Lesions [PDF]
This work is motivated by a study of a population of multiple sclerosis (MS) patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify active brain lesions.
Crainiceanu, Ciprian M.+4 more
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Migraine is a common disabling headache disorder characterized by recurrent episodes sometimes preceded or accompanied by focal neurological symptoms called aura. The relation between two subtypes, migraine without aura (MWoA) and migraine with aura (MWA)
Dahlem, Markus A.
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Spinal Cord Trauma: An Overview of Normal Structure and Function, Primary and Secondary Mechanisms of Injury, and Emerging Treatment Modalities [PDF]
The structures of the spinal cord and vertebral column are designed to provide flexibility, while still providing ample protection for the spinal cord deep within.
Morin, Daniel
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Postnatal meningeal CSF transport is primarily mediated by the arachnoid and pia maters and is not altered after intraventricular hemorrhage-posthemorrhagic hydrocephalus [PDF]
BACKGROUND: CSF has long been accepted to circulate throughout the subarachnoid space, which lies between the arachnoid and pia maters of the meninges. How the CSF interacts with the cellular components of the developing postnatal meninges including the ...
Alli, Abdul-Haq O+8 more
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Clinicopathological characteristics of histiocytic sarcoma affecting the central nervous system in dogs. [PDF]
BackgroundHistiocytic sarcoma affecting the central nervous system (CNS HS) in dogs may present as primary or disseminated disease, often characterized by inflammation.
Crowe, Chelsea M+10 more
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Efficacy of doripenem against Escherichia coli and Klebsiella pneumoniae in experimental meningitis [PDF]
Objectives In this study the efficacy of doripenem, a new broad-spectrum carbapenem, was tested against an Escherichia coli strain and a Klebsiella pneumoniae strain in an experimental animal model. The comparator was cefepime monotherapy.
Acosta, Fernando+5 more
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A review of acute bacterial meningitis in childhood [PDF]
This paper reviews the epidemiology, pathogenesis and management of acute bacterial meningitis in childhood. The epidemiology of this infection has undergone significant changes with the implementation of effective immunisation, antibiotic therapy and ...
Muscat Baron, Astrid, Muscat Baron, Yves
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Early- and late-migrating cranial neural crest cell populations have equivalent developmental potential in vivo [PDF]
We present the first in vivo study of the long-term fate and potential of early-migrating and late-migrating mesencephalic neural crest cell populations, by performing isochronic and heterochronic quail-to-chick grafts.
Baker, Clare V. H.+3 more
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