Results 41 to 50 of about 10,983 (153)
Meningoencephalitis in a Young Immunocompetent Patient
Cryptococcal meningitis is mainly seen in immunocompromised patients, but in recent years, there has been an increase in cases involving patients with no known immunodeficiencies. These patients have symptomatic presentations that range from indolent and
Michael Ke MD +3 more
doaj +1 more source
Aim: This study evaluated the use of polymerase chain reaction for cryptococcal meningitis diagnosis in clinical samples. Materials and methods: The sensitivity and specificity of the methodology were evaluated using eight Cryptococcus neoformans/C ...
Marilena dos Anjos Martins +5 more
doaj +1 more source
Background Clinicians may be less inclined to consider a diagnosis of cryptococcal meningitis in people without HIV infection or transplant-related immunosuppression. This may lead to a delay in diagnosis particularly if disseminated cryptococcal disease
Christopher Polk +3 more
doaj +1 more source
This report details a fatal case of fulminant disseminated cryptococcosis in a young male with undiagnosed HIV. He rapidly developed multi‐organ failure, refractory shock, and cardiac arrest. Autopsy revealed extensive myocardial cryptococcal infiltration and microemboli, suggesting a critical role in the acute refractory shock that led to his death ...
Taisei Sasamoto +3 more
wiley +1 more source
Central Nervous System Vasculitis for Cryptococcosis in an Immunocompetent Patient
Cryptococcal meningitis is a life-threatening condition caused by a fungal pathogen, Cryptococcus neoformans, that can infect both immunosuppressed and immunocompetent hosts. It is an important cause of morbidity and mortality in severely immunodeficient
Dan Zimelewicz Oberman +2 more
doaj +1 more source
Diagnosis and management of cryptococcal meningitis in HIV‐infected adolescents is challenging in poor resource settings. A high index of suspicion based on clinical presentation is critical for early identification and treatment.
Peter Puplampu +8 more
doaj +1 more source
Context: Cryptococcal meningitis is an opportunistic fungal infection which is seen among people with compromised cell-mediated immunity. It is an important cause of morbidity and mortality among HIV-positive patients.
Rajendra Prasad Shivaswamy +5 more
doaj +1 more source
Engineering Liposomes for Neurodegenerative Diseases: Targeted Delivery and Regenerative Potential
Liposomal nanocarriers offer therapeutic promise for neurodegenerative diseases by encapsulating diverse agents such as neurotrophic factors and mRNA while targeting the blood‐brain barrier. Designed to stimulate neuronal repair and restore function, these lipid vesicles advance strategies for optimized design and central nervous system delivery ...
Oybek Ashirov +3 more
wiley +1 more source
Objective To summarize the clinical manifestations and diagnostic and therapeutic strategies of 102 cases with cryptococcal meningitis and/or cryptococcal meningoencephalitis, and to improve the diagnosis and treatment of cryptococcal meningitis ...
Yan-yu CHANG, Xue-qiang HU
doaj
ABSTRACT Background and Aims Although the global plan aimed to eliminate mother‐to‐child transmission of HIV by 2015, an estimated 130,000 children were newly infected, and 84,000 children died from HIV related causes in 2022. In Ethiopia, 3200 children became newly infected and 1,900 children died from HIV related causes in 2022.
Amare Genetu Ejigu +19 more
wiley +1 more source

