Results 51 to 60 of about 498,582 (354)

Changing Epidemiology of Bacterial Meningitis Since Introduction of Conjugate Vaccines: 3 Decades of National Meningitis Surveillance in The Netherlands

Clinical Infectious Diseases, 2020
Background The epidemiology of acute bacterial meningitis has changed substantially since the introduction of conjugate vaccines. Methods We analyzed nationwide surveillance data of all cerebrospinal fluid isolates received by the Netherlands Reference ...
D. Koelman, Merel N. van Kassel, M. Bijlsma, M. Brouwer, D. van de Beek, A. van der Ende   +5 more
semanticscholar   +1 more source

The burden of RSV-associated illness in children aged < 5 years, South Africa, 2011 to 2016

BMC Medicine, 2023
Background Vaccines and monoclonal antibodies to protect the very young infant against the respiratory syncytial virus (RSV)-associated illness are effective for limited time periods.
Jocelyn Moyes, Stefano Tempia, Sibongile Walaza, Meredith L. McMorrow, Florette Treurnicht, Nicole Wolter, Anne von Gottberg, Kathleen Kahn, Adam L. Cohen, Halima Dawood, Ebrahim Variava, Cheryl Cohen   +11 more
doaj   +1 more source

Artificial Intelligence in Differential Diagnostics of Meningitis: A Nationwide Study

Diagnostics, 2021
Differential diagnosis between bacterial and viral meningitis is crucial. In our study, to differentiate bacterial vs. viral meningitis, three machine learning (ML) algorithms (multiple logistic regression (MLR), random forest (RF), and naïve-Bayes (NB))
Alexios-Fotios A. Mentis, Irene Garcia, Juan Jiménez, Maria Paparoupa, Athanasia Xirogianni, Anastasia Papandreou, Georgina Tzanakaki   +6 more
doaj   +1 more source

Methods for rapid diagnosis of meningitis etiology in adults

Biomarkers in Medicine, 2020
Infectious meningitis can be caused by viral, bacterial or fungal pathogens. Despite widely available treatments, many types of infectious meningitis are still associated with significant morbidity and mortality.
Victoria Poplin, D. Boulware, N. Bahr
semanticscholar   +1 more source

inPractice: a practical nursing package for clinical decisions [PDF]

, 2005
This paper examines the recent development of a computer-assisted learning program-in Practice-at the School of Health Science, in the University of Wales Swansea. The project, which began in 2001, was developed in close collaboration with The Meningitis
Cavanna, Annlouise, Corbett, Beverley, Ip, Barry   +2 more
core   +2 more sources

Rapidly shifting immunologic landscape and severity of SARS-CoV-2 in the Omicron era in South Africa

Nature Communications, 2023
Emergence of the Omicron BA.1/2 SARS-CoV-2 subvariants led to a wave of infection South Africa. Here, the authors use serological data from a prospective household study to characterise infection rates in the context of diverse immune histories following
Kaiyuan Sun, Stefano Tempia, Jackie Kleynhans, Anne von Gottberg, Meredith L. McMorrow, Nicole Wolter, Jinal N. Bhiman, Jocelyn Moyes, Maimuna Carrim, Neil A. Martinson, Kathleen Kahn, Limakatso Lebina, Jacques D. du Toit, Thulisa Mkhencele, Cécile Viboud, Cheryl Cohen, the PHIRST-C group   +16 more
doaj   +1 more source

Prolonged shedding of SARS-CoV-2 at high viral load amongst hospitalised immunocompromised persons living with HIV in South Africa

International Journal of Infectious Diseases, 2022
Purpose: There is limited information on SARS-CoV-2 shedding duration amongst persons living with HIV (PLWH). We hypothesised that PLWH shed SARS-CoV-2 for longer periods and at higher viral load than HIV-uninfected persons. Methods & Materials: From
S. Meiring, S. Tempia, J. Bhiman, J. Kleynhans, A. Buys, M. Makhasi, M. Mcmorrow, J. Moyes, V. Quan, S. Walaza, M. Du Plessis, N. Wolter, A. Von Gottberg, C. Cohen   +13 more
doaj   +1 more source

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance. [PDF]

, 2019
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
Aller, Altamirano, Arechavala, Bicanic, Bicanic, Boeva, Chang, Chen, Dannaoui, DePristo, Drusano, Harrison, Li, Longley, Loyse, Martin, Mayanja-Kizza, McKenna, Molloy, Mondon, Neely, Nixon, Nussbaum, Saag, Sionov, Sionov, Stone, Stott, Stott, Sudan, Wiederhold, Witt   +31 more
core   +1 more source

Febre purpúrica brasileira: resultados preliminares da investigação etiológica

Revista do Instituto de Medicina Tropical de São Paulo, 1987
Em várias regiões do interior do Estado de São Paulo, notificou-se a partir do final de 1984 a 1986, a ocorrência de doença até então desconhecida, com características clínicas, em muitos aspectos, semelhante à meningococcemia.
K. Irino, I. M. L. Lee, M. Kaku, M. C. C. Brandileone, C. E. A. Melles, C. E. Levy, S. E. Berkley, D. W. Fleming, G. A. Silva, L. Harrison   +9 more
doaj   +1 more source

Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing

JAMA Neurology, 2018
Importance Identifying infectious causes of subacute or chronic meningitis can be challenging. Enhanced, unbiased diagnostic approaches are needed.
M. Wilson, B. O’Donovan, J. Gelfand, H. Sample, F. Chow, John P. Betjemann, M. Shah, M. Richie, M. Gorman, R. Hajj-Ali, L. Calabrese, K. Zorn, E. Chow, J. Greenlee, J. Blum, G. Green, Lillian M. Khan, Debarko Banerji, C. Langelier, C. Bryson-Cahn, Whitney E. Harrington, Whitney E. Harrington, J. Lingappa, Niraj M. Shanbhag, A. Green, B. Brew, B. Brew, A. Soldatos, L. Strnad, S. Doernberg, C. Jay, V. Douglas, S. Josephson, J. Derisi   +33 more
semanticscholar   +1 more source