Results 101 to 110 of about 19,512 (262)
Fractional CO2 Laser Treatment for Female Vaginal Relaxation Syndrome: A Prospective Study
Lasers in Surgery and Medicine, EarlyView.ABSTRACT Background Vaginal relaxation syndrome (VRS) is a common condition that adversely affects women's quality of life. Conventional non‐surgical therapies provide limited benefit for patients with mild to moderate disease. Fractional CO2 laser (FxCO2) therapy has emerged as a minimally invasive treatment option; however, its long‐term efficacy and
Qiao Li +5 more
wiley +1 more source
Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization
Macromolecular Rapid Communications, EarlyView.Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou +6 more
wiley +1 more source
Transitioning the Menopause [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2020 openaire +2 more sources
Movement Disorders, EarlyView.Abstract Background Previous studies on calcium channel blockers (CCBs) and Parkinson's disease (PD) risk reached conflicting conclusions. Objectives We examined the relationship between CCBs and PD in the E3N cohort of French women followed for 15 years (2004–2018), while taking into account the potential for reverse causation.
Emilie Moutard +9 more
wiley +1 more source
Atlas of Brain Glucose Metabolism Using Deuterium Metabolic Imaging at 3 T
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose Deuterium metabolic imaging (DMI) offers noninvasive magnetic resonance imaging (MRI)–based assessment of metabolism in vivo, making it a relevant paraclinical tool for diseases with neurological metabolic alterations. This study aimed to establish a normative reference atlas of brain glucose metabolism accounting for age and sex ...
Kamilla K. Trosborg +14 more
wiley +1 more source
Neuroprotection, EarlyView.Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher +8 more
wiley +1 more source
Inflammation Associated With Obesity, Aging, and Amyloid Burden in Adults With Down Syndrome
Obesity, EarlyView.ABSTRACT Objective Adults with Down syndrome (DS) often show elevated systemic inflammation, but the association with obesity, aging, and Alzheimer's disease (AD) pathology is not well understood. Methods Data were drawn from 188 nondemented adults with DS participating in the Alzheimer Biomarkers Consortium‐DS (ABC‐DS). Participants completed clinical
Victoria L. Fleming‐Batayneh +80 more
wiley +1 more source
Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease
Portal Hypertension &Cirrhosis, EarlyView.MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang +5 more
wiley +1 more source
Descriptiveness complex AMG, Inhibin B, FSH in the diagnosis of menopause age
RUDN Journal of Medicine, 2013 The state of the ovaries in women who are in the perimenopausal period, studied the significance of ovarian reserve tests in predicting the onset of menopause and menopausal disorders.
G F Totchiev, N P Kotikova
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Precision Medical Sciences, EarlyView.Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang +7 more
wiley +1 more source