Results 131 to 140 of about 18,551 (242)

Risk of Sarcopenic Obesity Across Menopausal Transition Stages in Middle-Aged Korean Women. [PDF]

Nutrients
Cho Y, Jang Y, Park JH, Chang Y, Ryu S.
europepmc   +1 more source

Critical role of the mast cell/tryptase/PAR2 axis in anastrozole‐induced pain

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anastrozole, an aromatase inhibitor, is used to treat postmenopausal women with hormone receptor‐positive breast cancer, but also induces musculoskeletal pain and can lead to therapeutic regimen suspension. Aromatase inhibitors promote the release of pro‐inflammatory substances from sensitised nerve fibres, which might ...
Maria Fernanda Pessano Fialho, Raquel Tonello, Evelyne Silva Brum, Gabriela Becker, Nigel W. Bunnett, Sara Marchesan Oliveira   +5 more
wiley   +1 more source

Longitudinal patterns and group heterogeneity of depressive symptoms during menopausal transition in middle-aged Korean women. [PDF]

Epidemiol Psychiatr Sci
Jang Y, Chang Y, Park J, Jeon SW, Seo B, Park JH, Kang J, Kwon R, Lim GY, Kim KH, Kim H, Hong YS, Park J, Zhao D, Cho J, Guallar E, Ryu S.   +16 more
europepmc   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Menopausal transition in multiple sclerosis: relationship with disease activity and brain volume measurements. [PDF]

Front Neurol, 2023
Lorefice L, Fenu G, Fronza M, Murgia F, Frau J, Coghe G, Barracciu MA, Atzori L, Angioni S, Cocco E.   +9 more
europepmc   +1 more source

Effect Modification by Cofactors in the Impact of Body Mass Index Change on the Risk of Lung Cancer

Cancer Science, EarlyView.
Persistent overweight or obesity, and BMI gain from normal to overweight or obesity, were consistently associated with reduced lung cancer risk, with stronger associations among men and ever smokers. Persistent underweight and BMI loss were associated with increased lung cancer risk, particularly in men. The protective effect of obesity and BMI gain is
Su Youn Nam, Junwoo Jo, Sun Ha Choi
wiley   +1 more source

Longitudinal Association Between Menopausal Transition and Obstructive Sleep Apnea with Effect Modification by Salt Intake: A Prospective Cohort Study. [PDF]

Nutrients
Shin S, Jang Y, Chang Y, Ryu S.
europepmc   +1 more source

Gut microbiota and metabolites in estrus cycle and their changes in a menopausal transition rat model with typical neuroendocrine aging. [PDF]

Front Endocrinol (Lausanne), 2023
Dai R, Huang J, Cui L, Sun R, Qiu X, Wang Y, Sun Y.   +6 more
europepmc   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Perceived quality of sleep across the menopausal transition: A retrospective cohort study. [PDF]

Health Sci Rep, 2023
Maxwell RA, Reisinger-Kindle KM, Rackett TM, Yaklic JL, Czerwinski SA, Lee M.   +5 more
europepmc   +1 more source