Results 71 to 80 of about 5,680,524 (425)

The cognitive effects of adjunctive repetitive transcranial magnetic stimulation for late-onset depression: a randomized controlled trial with 4 week follow-up

open access: yesFrontiers in Psychiatry, 2023
ObjectivesCognitive impairment is common and linked to poor outcomes in patients with late-onset depression (LOD). The cognitive effects of repetitive transcranial magnetic stimulation (rTMS) for LOD are not well understood.
Wei-gang Pan   +13 more
doaj   +1 more source

A Snapshot of the Mental Health of Software Professionals [PDF]

open access: yesarXiv, 2023
Mental health disorders affect a large number of people, leading to many lives being lost every year. These disorders affect struggling individuals and businesses whose productivity decreases due to days of lost work or lower employee performance.
arxiv  

Relationship of cognitive decline with glucocerebrosidase activity and amyloid‐beta 42 in DLB and PD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) share clinical, pathological, and genetic risk factors, including GBA1 and APOEε4 mutations. Biomarkers associated with the pathways of these mutations, such as glucocerebrosidase enzyme (GCase) activity and amyloid‐beta 42 (Aβ42) levels, may hold potential as predictive ...
Maria Camila Gonzalez   +15 more
wiley   +1 more source

Association of hypertension and depression with mortality: an exploratory study with interaction and mediation models

open access: yesBMC Public Health
Background The association of hypertension and depression with mortality has not been fully understood. We aimed to explore the possible independent or joint association of hypertension and depression with mortality.
Huanhuan Huang   +8 more
doaj   +1 more source

Non-specialist health worker interventions for mental health care in low- and middle- income countries. [PDF]

open access: yes, 2011
This is the protocol for a review and there is no abstract. The objectives are as follows: OVERALL OBJECTIVE: In order to assess the impact of delivery by non-specialist health workers (NSHWs) and other professionals with health roles (OPHRs) on the ...
Altman   +45 more
core   +1 more source

Heterozygous variants in AP4S1 are not associated with a neurological phenotype

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Biallelic loss‐of‐function variants in AP4S1 cause childhood‐onset hereditary spastic paraplegia. A recent report suggested that heterozygous AP4S1 variants lead to a syndrome of lower limb spasticity and dysregulation of sphincter function. We critically evaluate this claim against clinical observations in 28 heterozygous carriers of the same
Vicente Quiroz   +9 more
wiley   +1 more source

The Chinese version of the immediate mood scaler (IMS): a study evaluating its validity, reliability, and responsiveness in patients with MDD in China

open access: yesBMC Psychiatry
Background It is important to timely capture the fluctuation of the symptoms related to major depressive disorder (MDD). However, most conventionally used assessment tools for MDD symptoms are not designed for real-time assessment.
Xiongying Chen   +5 more
doaj   +1 more source

Recent Progress in Mass Spectrometry-Based Metabolomics in Major Depressive Disorder Research

open access: yesMolecules, 2023
Major depressive disorder (MDD) is a serious mental illness with a heavy social burden, but its underlying molecular mechanisms remain unclear. Mass spectrometry (MS)-based metabolomics is providing new insights into the heterogeneous pathophysiology ...
Mingxia Liu   +4 more
doaj   +1 more source

A Robot Model of OC-Spectrum Disorders : Design Framework, Implementation and First Experiments [PDF]

open access: yes, 2019
© 2019 Massachusetts Institute of TechnologyComputational psychiatry is increasingly establishing itself as valuable discipline for understanding human mental disorders.
Adams R. A.   +15 more
core   +1 more source

Capturing what matters: Patient‐reported LGI1‐ANTibody encephalitis outcome RatiNg scale (LANTERN)

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Background LGI1‐antibody encephalitis (LGI1‐Ab‐E) is a common form of autoimmune encephalitis where most patients demonstrate ‘good’ clinician‐rated outcomes. However, more targeted questionnaires reveal numerous debilitating symptoms for many years.
Mark J Kelly   +9 more
wiley   +1 more source

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