Results 71 to 80 of about 342,093 (301)

Orientasi Happiness Pada Orangtua Yang Memiliki Anak Tunagrahita Ringan [PDF]

, 2017
The purposes of this study were: 1) assess the orientation of happiness in mothers of children with mild mental retardation, 2) assess the orientation of happiness in the fathers who have children with mild mental retardation. This study is a qualitative
Na'imah, T. (Tri), Nur'aeni, N. (Nur'aeni), Septiningsih, D. S. (Dyah)   +2 more
core   +2 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

Neurobiology of Disease, 2011
Emerging evidence points to reactive glia as a pivotal factor in Parkinson's disease (PD) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned mouse model of basal ganglia injury, but whether astrocytes and microglia activation may exacerbate
F. L'Episcopo, C. Tirolo, N. Testa, S. Caniglia, M.C. Morale, C. Cossetti, P. D'Adamo, E. Zardini, L. Andreoni, A.E.C. Ihekwaba, P.A. Serra, D. Franciotta, G. Martino, S. Pluchino, B. Marchetti   +14 more
doaj   +1 more source

11p Microdeletion including WT1 but not PAX6, presenting with cataract, mental retardation, genital abnormalities and seizures: a case report [PDF]

, 2009
Udgivelsesdato: 2009-nullABSTRACT: WAGR syndrome (Wilms' tumor, aniridia, genitourinary abnormalities and mental retardation) and Potocki-Shaffer syndrome are rare contiguous gene deletion syndromes caused by deletions of the 11p14-p12 chromosome region ...
Gitte J Almind, Karen Brøndum-Nielsen, Regitze Bangsgaard, Peter Baekgaard, Karen Grønskov   +4 more
core   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

MORPHOFUNCTIONAL AND PSYCHOPHYSIOLOGICAL FEATURES IN CHILDREN WITH INTELLECTUAL DISORDERS

Вестник Кемеровского государственного университета, 2017
The article studies morphofunctional and psychophysiological features in children with mental disabilities. The research features 7–9-year-old children, both male and female, with different central nervous system diseases (various degrees of mental ...
Nina G. Blinova, Nataliya N. Koshko, Ramil M. Akbirov   +2 more
doaj   +1 more source

Learning from Other Communities [PDF]

, 2006
This paper reflects a synopsis of the work in person/family-centered planning representative of its implementation across a variety of disability service systems, including prisons, schools, community-based service agencies and institutional settings ...
Abery, Brian, Allegretti-Freeman, John, Blessing, Carol, Osher, David, Tierney, Mary   +4 more
core   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Sphingomyelinase activity at pH 7.4 in human brain and a comparison to activity at pH 5.0

Journal of Lipid Research, 1976
A hitherto undescribed sphingomyelinase (sph'ase 7.4) of human brain has been studied in crude and partially purified (3- to 4- fold) extracts of grey matter, and compared to the known sphingomyelinase with an acid pH optimum (sph'ase 5.0).
B G Rao, Dr M W Spence
doaj   +1 more source

Pengaruh Terapi Self-Help Groupterhadap Koping Keluarga Dengan Anak Retardasi Mental [PDF]

, 2014
Family with children having mental retardation at Sumedang district are almost 10,898 childrenof 1,089,889 population and they are only 218 children which recorded at SLB-C at Sumedang district.
Gayatri, D. (Dewi), Keliat, B. A. (Budi), Sutini, T. (Titin)   +2 more
core   +1 more source