Results 101 to 110 of about 7,679 (193)

Real-World Effectiveness of Mepolizumab in Patients with Severe Asthma: An Examination of Exacerbations and Costs

Journal of Asthma and Allergy, 2020
Jean-Pierre Llanos,1 Hector Ortega,1 Michael Bogart,2 Elizabeth R Packnett,3 Janna Manjelievskaia,3 Christopher F Bell,2 Beth Hahn2 1Respiratory, US Medical Affairs, GSK, Research Triangle Park, NC, USA; 2US Value Evidence and Outcomes, US Medical ...
Llanos JP, Ortega H, Bogart M, Packnett ER, Manjelievskaia J, Bell CF, Hahn B   +6 more
doaj  

Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators

Allergy, EarlyView.
Jaime Bernaola, José Antonio Cañas, Álvaro Arranz‐Fragua, José Manuel Rodrigo‐Muñoz, Daniel Rodríguez‐González, Antonio Serrano‐Santiago, Gema Guillén‐Sánchez, Alma Martínez Fernández, Marcela Valverde‐Monge, Diana Betancor, Erwin Javier Pinillos‐Robles, Claudia Rodríguez‐Busto, María Jesús Rodríguez‐Nieto, Joaquín Sastre, Victoria del Pozo   +14 more
wiley   +1 more source

The Effect of Mepolizumab on Blood Eosinophil Subtype Distribution and Granule Protein Gene Expression in Severe Eosinophilic Asthma [PDF]

Airidas Rimkunas,1 Andrius Januskevicius,1 Egle Vasyle,1 Jolita Palacionyte,2 Virginija Kalinauskaite-Zukauske,2 Skaidrius Miliauskas,2 Kestutis Malakauskas1,2 1Laboratory of Pulmonology, Department of Pulmonology, Lithuanian University of Health ...
Palacionyte J, Rimkunas A, Vasyle E, Malakauskas K, Miliauskas S, Kalinauskaite-Zukauske V, Januskevicius A   +6 more
core   +1 more source

The spectrum of therapeutic activity of mepolizumab [PDF]

, 2019
Introduction: The basis of the development of the anti-interleukin-5 monoclonal antibody mepolizumab was the acknowledgment of the crucial importance of this cytokine in promoting eosinophils production, activation, and survival, which is associated with
Cavaliere C., Ridolo E., Masieri S., Incorvaia C., de Vincentiis M., Greco A., Frati F., Makri E.   +7 more
core   +1 more source

Peak nasal inspiratory flow assessment of polyp size and response from SYNAPSE

Journal of Allergy and Clinical Immunology: Global
Background: In the phase III SYNAPSE study, mepolizumab plus standard of care reduced total endoscopic nasal polyp score (NPS) versus that with placebo in patients with chronic rhinosinusitis with nasal polyps.
Amber U. Luong, MD, PhD, Joshua M. Levy, MD, MPH, MSc, Ludger Klimek, MD, PhD, Richard J. Harvey, MD, Jared Silver, MD, PhD, Steven G. Smith, PhD, Abby Fuller, MSc, Robert Chan, MD, Peter W. Hellings, MD, PhD   +8 more
doaj   +1 more source

Mepolizumab for prednisone-dependent asthma with sputum eosinophilia [PDF]

, 2009
BACKGROUND Eosinophilic inflammation, which may be a consequence of interleukin-5 action, is a characteristic feature of some forms of asthma. However, in three previous clinical trials involving patients with asthma, blockade of this cytokine did not ...
O'Byrne, Paul M., Pizzichini, M. M M, Pizzichini, Emilio, Kjarsgaard, Melanie, Hargreave, Frederick E., Nair, Parameswaran, Efthimiadis, Ann, Inman, Mark D.   +7 more
core   +1 more source

Early Intervention with Mepolizumab, Corticosteroids, and Intravenous Immunoglobulin for Dupilumab-Triggered Eosinophilic Granulomatosis with Polyangiitis: A Case Report [PDF]

Shota Kaburaki, Toru Tanaka, Koichiro Kamio, Yosuke Tanaka, Kazuo Kasahara, Masahiro Seike Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, JapanCorrespondence: Shota Kaburaki, Department of ...
Kamio K, Tanaka Y, Seike M, Tanaka T, Kaburaki S, Kasahara K   +5 more
core   +1 more source

Eosinophilia Reflects Type 2 Immune Activation in Newly Diagnosed Bullous Pemphigoid, With No Evidence of Charcot‐Leyden Crystals

Allergy, EarlyView.
Janik Fleißner, Tassilo Dege, Sandrine Benoit, Matthias Goebeler, Andreas Kerstan   +4 more
wiley   +1 more source

Functional Endoscopic Sinus Surgery in Adults With CRSwNP Treated With Mepolizumab: Airway Physiology Outcomes From a Randomised Controlled Trial

Clinical &Experimental Allergy, EarlyView.
Jens Tidemandsen, Anne Sophie Homøe, Peter G. Gibson, Howraman Meteran, Kasper Aanæs, Morten Hostrup, Marie Høxbro, Vibeke Backer   +7 more
wiley   +1 more source

Serum Eosinophil‐Derived Neurotoxin (EDN) as a Biomarker for Treatment Response in Atopic Dermatitis

Clinical &Experimental Allergy, EarlyView.
J. I. Olydam, S. Sengkerij, S. Veenbergen, D. J. Hijnen   +3 more
wiley   +1 more source