Results 81 to 90 of about 5,545 (148)

Estudio de utilización de omalizumab y mepolizumab en asma refractaria grave [PDF]

, 2018
Introducción. En los últimos años, se han comercializado diferentes fármacos biológicos dirigidos a dianas específicas del asma, como el omalizumab y mepolizumab.
López Cárdenas, Mª Teresa
core  

Patterns and Clinical Efficacy of Biologics Switching in Patients With Severe Asthma: A Systematic Review and Meta‐Analysis

Allergy, Volume 81, Issue 5, Page 1548-1570, May 2026.
This meta‐analysis included 2292 patients with severe asthma who underwent biologic switching across 23 countries/regions. The most prevalent switching pattern was from mepolizumab to benralizumab, with suboptimal asthma control being the primary reason.
Yang Zheng, Ya‐chun Li, Sheng‐jie Li, Meng Xu, Jia‐qian Hu, Wen‐qu Tian, Shi‐wei Chen, Xue‐hui Li, Ying He, Gan Lu, Mübeccel Akdis, Ioana Agache, Cezmi A. Akdis, Ya‐dong Gao   +13 more
wiley   +1 more source

Wells syndrome: clinical findings and treatment management in a large cohort of 48 patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 5, Page 644-656, May 2026.
Summary Background and Objectives: Wells syndrome (WS) is a rare inflammatory skin disorder typically characterized by erythematous, edematous, and pruritic plaques. Despite its distinct histopathological features, WS remains an underdiagnosed disease due to its variable clinical presentations and overlap with other dermatological conditions.
Marco Adriano Chessa, Silvia Robuffo, Tullio Brunetti, Luca Rapparini, Bianca Maria Piraccini, Cosimo Misciali, Beatrice Raone, Iria Neri, Federica Filippi   +8 more
wiley   +1 more source

Real-world characteristics and disease burden of patients with asthma prior to treatment initiation with mepolizumab or omalizumab: a retrospective cohort database study

Journal of Asthma and Allergy, 2019
Jean-Pierre Llanos,1 Christopher F Bell,1 Elizabeth Packnett,2 Ellen Thiel,2 Debra E Irwin,2 Beth Hahn,1 Hector Ortega3 1Respiratory, US Medical Affairs, GSK, Research Triangle Park, NC, USA; 2Truven Health Analytics, An IBM Watson Health Company, Ann ...
Llanos JP, Bell CF, Packnett E, Thiel E, Irwin DE, Hahn B, Ortega H   +6 more
doaj  

Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma

, 2019
Systemic/oral corticosteroids (OCS) have been used for decades in the management of acute asthma exacerbations and chronically in patients with uncontrolled severe asthma.
Bousquet, Jean, Brusselle, Guy, Buhl, Roland, Katsaounou, Paraskevi, Martinez, Rafael, Pfister, Pascal, Wahn, Ulrich   +6 more
core   +1 more source

Rhinology future debates, an EUFOREA report [PDF]

, 2017
The first Rhinology Future Debates was held in Brussels in December 2016, organized by EUFOREA (European Forum for Research and Education in Allergy and Airways diseases).
Bachert, Claus, Bernal-Sprekelsen, Manuel, Bousquet, Jean, Djandji, Michel, Dorenbaum, Alejandro, Fokkens, Wytske J, Hakim-Mehr, Dorna, Hellings, Peter W, Hendry, Stuart, Hopkins, Claire, Leunig, Andreas, Mannent, Leda, Mucha, Dirk, Onerci, Metin, Pugin, Benoit, Rowe, Paul, Seys, Sven F, Stimson, Susan, Strzembosz, Agnieszka, Toppila-Salmi, Sanna   +19 more
core   +2 more sources

The Secretome of Bullous Pemphigoid IgG‐Treated Keratinocytes Induces a Pro‐Inflammatory Eosinophil Response

Experimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease whereby the cutaneous antigens BP180 and BP230 are targeted by autoantibodies. Skin lesions in BP are characterized by an abundance of eosinophils. We recently demonstrated that the treatment of keratinocytes with antibodies from patients with BP induces a robust inflammatory response
Adrian P. Mansini, Lei Bao, Krishan D. Chhiba, Jing Li, Yulu Wang, Haley Gainer, M. Allen McAlexander, Christopher McCrae, Christopher D. Nazaroff, Fei Li Kuang, Kyle T. Amber   +10 more
wiley   +1 more source

Anti-Interleukin-5-Therapie bei eosinophilen Erkrankungen [PDF]

, 2018
Zusammenfassung: Bei einer Reihe von Erkrankungen, die durch eine Eosinophilie charakterisiert sind, findet man erhöhte Spiegel von Interleukin- (IL-)5 im Blut und/oder Gewebe.
Braathen, L.R., Simon, D., Simon, H.-U
core  

Preliminary Clinical Outcomes of Human Umbilical Cord Mesenchymal Stem Cell‐Derived Exosomes in Chronic Rhinosinusitis With Nasal Polyps: A Case Report

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a persistent inflammatory disease that may be resistant to medical management and recurs with traditional surgery. We report a 28‐year‐old male with a history of CRSwNP with comorbid asthma, who was resistant to all medical management, including saline irrigation, intranasal corticosteroids (
Manoochehr Avatef‐Fazeli, Gelavizh Rostaminasab, Iman Janghorban Esfahani, Amir Barimani, Kamran Mansouri   +4 more
wiley   +1 more source

Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators

Allergy, EarlyView.
Jaime Bernaola, José Antonio Cañas, Álvaro Arranz‐Fragua, José Manuel Rodrigo‐Muñoz, Daniel Rodríguez‐González, Antonio Serrano‐Santiago, Gema Guillén‐Sánchez, Alma Martínez Fernández, Marcela Valverde‐Monge, Diana Betancor, Erwin Javier Pinillos‐Robles, Claudia Rodríguez‐Busto, María Jesús Rodríguez‐Nieto, Joaquín Sastre, Victoria del Pozo   +14 more
wiley   +1 more source