Results 141 to 150 of about 13,707 (310)

Extension of mepolizumab injection intervals as potential of saving costs in well controlled patients with severe eosinophilic asthma

World Allergy Organization Journal, 2022
Background: Present guidelines recommend a life-long therapy with mepolizumab in patients suffering from severe eosinophilic asthma as several studies proved the disadvantages of treatment cessation.
Georg Bölke, MD, Xunliang Tong, MD, Torsten Zuberbier, MD, PhD, Jean Bousquet, MD, PhD, Karl-Christian Bergmann, MD, PhD   +4 more
doaj  

Mepolizumab for Prednisone-Dependent Asthma with Sputum Eosinophilia [PDF]

, 2009
Parameswaran Nair, Márcia Margaret Menezes Pizzichini, Melanie Kjarsgaard, Mark D. Inman, Ann Efthimiadis, Emílio Pizzichini, Frederick E. Hargreave, Paul M. O’Byrne   +7 more
openalex   +1 more source

Clinical Remission Criteria and Serum Levels of Type 2 Inflammation Mediators during 24 Weeks of Treatment with the Anti-IL-5 Drug Mepolizumab in Patients with T2-High Severe Asthma

Diagnostics
Anti-interleukin (IL) 5 is an effective treatment modality for inhibiting eosinophilic inflammation in patients with T2-high severe asthma. The aim of this study was to determine the clinical efficacy and serum levels of type 2 inflammatory mediators ...
J. Palacionyte, A. Januskevicius, E. Vasyle, A. Rimkunas, S. Miliauskas, K. Malakauskas   +5 more
semanticscholar   +1 more source

Mepolizumab in chronic rhinosinusitis with nasal polyps: Real life data in a multicentric Sicilian experience [PDF]

Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by a type 2 pattern of inflammation. Mepolizumab was approved for the treatment of CRSwNP in 2021. However, there is a lack of real-life studies.
Barbieri, Maria Antonietta, Ciodaro, Francesco, Diana, Mariut, Dispensa, Francesco, Frangipane, Silvia, Freni, Francesco, Galletti, Bruno, Galletti, Cosimo, Galletti, Francesco, Gallina, Salvatore, Immordino, Angelo, La Mantia, Ignazio, Lorusso, Francesco, Manzella, Riccardo, Messina, Giuliano, Portelli, Daniele, Sireci, Federico, Stilo, Giovanna, Zappalà, Andrea Guglielmo   +18 more
core   +1 more source

Mepolizumab does not alter levels of eosinophils, T cells, and mast cells in the duodenal mucosa in eosinophilic esophagitis [PDF]

, 2010
Sébastien Conus, Alex Straumann, Eva Bettler, Hans‐Uwe Simon   +3 more
openalex   +1 more source

Superiority of Avacopan and Mepolizumab to Glucocorticoid Tapering in the Treatment of Anti-neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis: A Systematic Review

Cureus
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) comprises a spectrum of autoimmune diseases, including granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA)
Rishma Gattu, Michelle Demory Beckler, Marc M. Kesselman   +2 more
semanticscholar   +1 more source

Sustained Effectiveness of Benralizumab in Naïve and Biologics-Experienced Severe Eosinophilic Asthma Patients: Results from the ANANKE Study [PDF]

Purpose: Severe eosinophilic asthma (SEA) patients often present overlapping inflammatory features rendering them eligible for multiple biologic therapies; switching biologic treatment is a strategy adopted to optimize asthma control when patients show ...
Aliani, Maria, Altieri, Elena, Benci, Marco, Boarino, Silvia, Bracciale, Pietro, Brussino, Luisa, Caiaffa, Maria Filomena, Cameli, Paolo, Canonica, Giorgio, Caruso, Cristiano, Centanni, Stefano, D'Amato, Maria, De Michele, Fausto, Del Giacco, Stefano, Di Marco, Fabiano, Menzella, Francesco, Pelaia, Girolamo, Rogliani, Paola, Romagnoli, Micaela, Schino, Pietro, Schroeder, Jan Walter, Senna, Gianenrico, Vultaggio, Alessandra   +22 more
core   +4 more sources

The Pharmacodynamic Effects of Mepolizumab, a Humanized Monoclonal Antibody Against IL-5, in Pediatric Patients with Eosinophilic Esophagitis: A Randomized, Double-blind, Controlled Clinical Trial [PDF]

, 2010
Amal Assa’ad, Seema S. Aceves, Sandeep K. Gupta, Éric Drouin, Margaret H. Collins, C H Jurgensen, A. Heath, T. Perschy, Jessal J. Patel, Héctor Ortega   +9 more
openalex   +1 more source

Mepolizumab and COPD in Real Life

Open Respiratory Archives, 2022
Fernando Revuelta-Salgado, Ascensión Hernando-Sanz, Carlos Melero-Moreno, Rocío Magdalena Díaz-Campos   +3 more
openaire   +3 more sources

Mepolizumab, a humanized anti–IL-5 mAb, as a treatment option for severe nasal polyposis [PDF]

, 2011
Philippe Gevaert, Nicholas Van Bruaene, Tom Cattaert, Kristel Van Steen, Thibaut Van Zele, Frederic Acke, Natalie De Ruyck, Katrien Blomme, Ana R. Sousa, Richard P. Marshall, Claus Bachert   +10 more
openalex   +1 more source