Results 121 to 128 of about 403 (128)

Comparative Metabolism of Mequindox in Liver Microsomes, Hepatocytes, and Intestinal Microflora of Chicken

Analytical Letters, 2012
Drug metabolism studies in vitro were carried out inexpensively and readily to serve as an adequate mechanism to characterize drug metabolites, elucidate their pathways, and make suggestions for further testing in vivo. In this work, the comparative metabolism of mequindox (MEQ) was investigated in vitro by incubation with chicken liver microsomes ...
Yan Li, Linxia Li, Jianzhong Shen, Suxia Zhang, Peisheng Feng, Haixia Wu, Congming Wu   +6 more
semanticscholar   +2 more sources

Interactions of NADPH oxidase, renin-angiotensin-aldosterone system and reactive oxygen species in mequindox-mediated aldosterone secretion in Wistar rats.

Toxicology Letters, 2010
High doses of mequindox (MEQ) are associated with oxidative stress and pathological toxicity in the kidney. In this study, we demonstrated long term effects of MEQ on intra- or extra-adrenal renin-angiotensin-aldosterone system (RAAS) in vivo. RAAS plays a major role in aldosterone secretion.
Xianju Huang, Xu Wang, Awais Ihsan, Qin Liu, Xijuan Xue, S. Su, Chunhui Yang, Wen-Hu Zhou, Zonghui Yuan   +8 more
semanticscholar   +3 more sources

Spectroscopic Studies on the Binding of Bacteriophage Mequindox with Bovine Serum Albumin

Chinese Journal of Chemistry, 2009
AbstractFluorescence spectra and UV‐Vis absorption spectra have been used to study the binding of bacteriophage mequindox (MEQ) with bovine serum albumin (BSA), which performed a dynamic quenching process. The quenching constants and thermodynamic parameters at different temperatures were calculated.
Zhouhua ZENG, Yi LIU, Xianming HU, Zhenqiang XU, Kun ZENG   +4 more
openaire   +1 more source

Long-term dose-dependent response of Mequindox on aldosterone, corticosterone and five steroidogenic enzyme mRNAs in the adrenal of male rats.

Toxicology Letters, 2009
Mequindox (MEQ) is a synthetic quinoxaline 1,4-dioxides (QdNOs) derivative which can effectively improve growth and feed efficiency in animals. This study was to investigate the dose-dependent long-term toxicity in the adrenal of male rats exposed to 180 days of MEQ feed.
Xianju Huang, Awais Ihsan, Xu Wang, Menghong Dai, Yulian Wang, S. Su, Xijuan Xue, Zonghui Yuan   +7 more
semanticscholar   +3 more sources

The structure elucidation of mequindox and 1,4-bisdesoxymequindox: NMR analyses, FT-IR spectra, DFT calculations and thermochemical studies

Journal of Molecular Structure, 2011
In the current work, we report a combined experimental and theoretical study on the molecular conformation, vibrational spectra, and nuclear magnetic resonance (NMR) spectra of mequindox (MEQ) and 1,4-bisdesoxymequindox (1,4-BDM). The geometric structure and vibrational frequencies of MEQ and 1,4-BDM have been calculated by density functional theory ...
Jiaheng Zhang, Xin He, Haixiang Gao
openaire   +1 more source

Determination of Carbadox, Cyadox, Mequindox, and Quinocetone Metabolites in Livestock Products by HPLC–MS/MS

Journal of Analytical Chemistry
A. Zhedulov, A. Sorokin, D. Nekrasov, E. I. Mamedova, I. V. Batov   +4 more
semanticscholar   +1 more source

Identification of Mequindox and Its Metabolites by High Performance Liquid Chromatography Combined with Ion Trap-Time of Flight-Mass Spectrometry

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION), 2010
Ying-Chun LIU, Hong-Bin SI, Li-Min HE, Huan-Zhong DING, Xian-Hui HUANG, Jian-Xin CHEN, Zhang-Liu CHEN, Zhen-Ling ZENG   +7 more
openaire   +1 more source

Metabolism of Mequindox in Scophthalmus Maximus by Liquid Chromatography High–Resolution Mass Spectrometry

Yanshen Li, Xinru Li, Haoxian An, Chaofan Yuan, Yanli You, Shuang Zhou, Xin Mao   +6 more
openaire   +1 more source