Results 31 to 40 of about 232 (109)

N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by [PDF]

, 2020
Quinoxaline-1,4-dioxides (QdNOs) are a class of quinoxaline derivatives that are widely used in humans or animals as drugs or feed additives. However, the metabolic mechanism, especially the involved enzymes, has not been reported in detail.
Yiqun Deng, Qingmei Chen, Ming Xu, Peiqiang Mu, Yuanming Zheng, Yufan Wang, Kaixin Wu, Oxidase Ssaox1, Porcine Aldehyde, Ming Zheng, Xianqing Tang, Lijuan Wang   +11 more
core  

Pharmacokinetics of Mequindox and Its Marker Residue 1,4-Bisdesoxymequindox in Swine Following Multiple Oral Gavage and Intramuscular Administration: An Experimental Study Coupled with Population Physiologically Based Pharmacokinetic Modeling

, 2017
Mequindox (MEQ) is a quinoxaline-N,N-dioxide antibiotic used in food-producing animals. MEQ residue in animal-derived foods is a food safety concern. The tissue distribution of MEQ and its marker residue 1,4-bisdesoxymequindox (M1) were determined in ...
Dongping Zeng, Riviere, Jim E, Miao Li, Jim E. Riviere, Zeng, Dongping, Zhenling Zeng, Ronette Gehring, Binghu Fang, Gehring, Ronette, Zhoumeng Lin, Zeng, Zhenling, Fang, Binghu, Lin, Zhoumeng, Li, Miao   +13 more
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Image_6_Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse.JPEG

, 2018
Mequindox (MEQ), belonging to quinoxaline-di-N-oxides (QdNOs), is a synthetic antimicrobial agent widely used in China. Previous studies found that the kidney was one of the main toxic target organs of the QdNOs.
Zhixin Lei (5079332), Qinghua Wu (79148), Jingchao Guo (5155970), Zainab Fatima (650655), Aimei Liu (5155967), Muhammad Kashif Maan (5155973), Xu Wang (28596), Menghong Dai (309784), Qianying Liu (5079338), Haseeb Khaliq (751367), Yuanhu Pan (625035), Muhammad A. B. Shabbir (5155964), Zonghui Yuan (309797), Qirong Lu (5155976)   +13 more
core   +1 more source

Image_1_Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse.JPEG

, 2018
Mequindox (MEQ), belonging to quinoxaline-di-N-oxides (QdNOs), is a synthetic antimicrobial agent widely used in China. Previous studies found that the kidney was one of the main toxic target organs of the QdNOs.
Zhixin Lei (5079332), Qinghua Wu (79148), Jingchao Guo (5155970), Zainab Fatima (650655), Aimei Liu (5155967), Muhammad Kashif Maan (5155973), Xu Wang (28596), Menghong Dai (309784), Qianying Liu (5079338), Haseeb Khaliq (751367), Yuanhu Pan (625035), Muhammad A. B. Shabbir (5155964), Zonghui Yuan (309797), Qirong Lu (5155976)   +13 more
core   +1 more source

Image_3_Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse.JPEG

, 2018
Mequindox (MEQ), belonging to quinoxaline-di-N-oxides (QdNOs), is a synthetic antimicrobial agent widely used in China. Previous studies found that the kidney was one of the main toxic target organs of the QdNOs.
Zhixin Lei (5079332), Qinghua Wu (79148), Jingchao Guo (5155970), Zainab Fatima (650655), Aimei Liu (5155967), Muhammad Kashif Maan (5155973), Xu Wang (28596), Menghong Dai (309784), Qianying Liu (5079338), Haseeb Khaliq (751367), Yuanhu Pan (625035), Muhammad A. B. Shabbir (5155964), Zonghui Yuan (309797), Qirong Lu (5155976)   +13 more
core   +1 more source

Image_2_Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse.JPEG

, 2018
Mequindox (MEQ), belonging to quinoxaline-di-N-oxides (QdNOs), is a synthetic antimicrobial agent widely used in China. Previous studies found that the kidney was one of the main toxic target organs of the QdNOs.
Zhixin Lei (5079332), Qinghua Wu (79148), Jingchao Guo (5155970), Zainab Fatima (650655), Aimei Liu (5155967), Muhammad Kashif Maan (5155973), Xu Wang (28596), Menghong Dai (309784), Qianying Liu (5079338), Haseeb Khaliq (751367), Yuanhu Pan (625035), Muhammad A. B. Shabbir (5155964), Zonghui Yuan (309797), Qirong Lu (5155976)   +13 more
core   +1 more source

Image_5_Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse.JPEG

, 2018
Mequindox (MEQ), belonging to quinoxaline-di-N-oxides (QdNOs), is a synthetic antimicrobial agent widely used in China. Previous studies found that the kidney was one of the main toxic target organs of the QdNOs.
Zhixin Lei (5079332), Qinghua Wu (79148), Jingchao Guo (5155970), Zainab Fatima (650655), Aimei Liu (5155967), Muhammad Kashif Maan (5155973), Xu Wang (28596), Menghong Dai (309784), Qianying Liu (5079338), Haseeb Khaliq (751367), Yuanhu Pan (625035), Muhammad A. B. Shabbir (5155964), Zonghui Yuan (309797), Qirong Lu (5155976)   +13 more
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Identification of Mequindox and Its Metabolites by High Performance Liquid Chromatography Combined with Ion Trap-Time of Flight-Mass Spectrometry

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION), 2010
Ying-Chun LIU, Hong-Bin SI, Li-Min HE, Huan-Zhong DING, Xian-Hui HUANG, Jian-Xin CHEN, Zhang-Liu CHEN, Zhen-Ling ZENG   +7 more
openaire   +2 more sources

Table_3_Mequindox Induced Genotoxicity and Carcinogenicity in Mice.PDF

, 2018
Mequindox (MEQ), acting as an inhibitor of deoxyribonucleic acid (DNA) synthesis, is a synthetic heterocyclic N-oxides. To investigate the potential carcinogenicity of MEQ, four groups of Kun-Ming (KM) mice (50 mice/sex/group) were fed with diets ...
Zhixin Lei (5079332), Deyu Huang (5079335), Shuyu Xie (2891090), Qin Wu (139038), Qianying Liu (5079338), Yuanhu Pan (625035), Xu Wang (28596), Zonghui Yuan (309797)   +7 more
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Table_4_Mequindox Induced Genotoxicity and Carcinogenicity in Mice.PDF

, 2018
Mequindox (MEQ), acting as an inhibitor of deoxyribonucleic acid (DNA) synthesis, is a synthetic heterocyclic N-oxides. To investigate the potential carcinogenicity of MEQ, four groups of Kun-Ming (KM) mice (50 mice/sex/group) were fed with diets ...
Zhixin Lei (5079332), Deyu Huang (5079335), Shuyu Xie (2891090), Qin Wu (139038), Qianying Liu (5079338), Yuanhu Pan (625035), Xu Wang (28596), Zonghui Yuan (309797)   +7 more
core   +1 more source