Results 11 to 20 of about 45,996 (263)
Merkel Cell Polyomavirus and Merkel Cell Carcinoma [PDF]
Cancers, 2020 Merkel cell carcinoma (MCC) is a rare, highly aggressive neuroendocrine skin cancer. More than 80% of MCC have Merkel cell polyomavirus (MCPyV) clonally integrated into the human genome (VP-MCC) while the remaining 20% are virus negative (VN-MCC) but ...
Rasheed, Kashif
core +10 more sources
Skin Health and Disease, 2021 Merkel cell carcinoma is a rare, highly aggressive primary cutaneous tumor, predominantly affecting older patients. The pathogenesis is associated with either Merkel cell polyomavirus infection or UV-mediated damage caused by chronic sun exposure: virus ...
Bossi P. +5 more
core +6 more sources
Multiple gastrointestinal metastases of Merkel cell carcinoma
Medicina, 2016 Merkel cell carcinoma is an aggressive skin malignancy. Primary Merkel cell carcinomas are treated by wide radical excision with or without adjuvant radiotherapy, while benefits of adjuvant chemotherapy remain doubtful.
Eligijus Poškus +5 more
doaj +2 more sources
Merkel cell carcinoma in an immunosuppressed patient [PDF]
Anais Brasileiros de Dermatologia, 2017 Merkel cell carcinoma is an uncommon neuroendocrine carcinoma with a rising incidence and an aggressive behavior. It predominantly occurs in older patients, with onset occurring at a mean age of 75-80 years.
Heliana Freitas de Oliveira Góes +5 more
doaj +2 more sources
Dermatologic Clinics, 2023 Merkel cell carcinoma (MCC) is a rare tumor that arises from mechanoreceptor Merkel cells. Ultraviolet exposure, immunosuppression and Merkel cell polyoma virus play a significant role in tumor pathogenesis. Although it typically presents as an initially
Akdemir, Osman Cemil +5 more
core +3 more sources
Merkel cell polyomavirus strains in patients with merkel cell carcinoma [PDF]
Emerging Infectious Diseases, 2009 International audienceWe investigated whether Merkel cell carcinoma (MCC) patients in France carry Merkel cell polyomavirus (MCPyV) and then identified strain variations. All frozen MCC specimens and 45% of formalin-fixed and paraffin-embedded specimens,
Durlach, Anne +21 more
core +5 more sources
Review Authorized Biography Angela Merkel
European Journal of Life Writing, 2014 With Angela Merkel favoured to win the German election again, several political books about the German chancellor were published during 2013. Both in Germany and abroad, observers puzzled over the reasons for the on-going success of Mrs.
Marieke Oprel
doaj +2 more sources
Surgical Pathology Clinics, 2017 Merkel cell carcinoma (MCC) encompasses neuroendocrine carcinomas primary to skin and occurs most commonly in association with clonally integrated Merkel cell polyomavirus with related retinoblastoma protein sequestration or in association with UV radiation-induced alterations involving the TP53 gene and mutations, heterozygous deletion, and ...
Becker, Jürgen +6 more
+9 more sources
Merkel cell polyomavirus and associated Merkel cell carcinoma
Tumour Virus Research, 2022 Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate. Since the discovery of MCPyV in 2008, great advances have been made to improve our understanding of how the viral encoded oncoproteins contribute to MCC oncogenesis.
June F. Yang, Jianxin You
openaire +3 more sources
Merkel cell polyomavirus infection and Merkel cell carcinoma [PDF]
Current Opinion in Virology, 2016 Merkel cell polyomavirus is the only polyomavirus discovered to date that is associated with a human cancer. MCPyV infection is highly prevalent in the general population. Nearly all healthy adults asymptomatically shed MCPyV from their skin. However, in elderly and immunosuppressed individuals, the infection can lead to a lethal form of skin cancer ...
Wei, Liu, Margo, MacDonald, Jianxin, You
openaire +2 more sources