Results 41 to 50 of about 45,996 (263)
Nishi Nihon Hifuka, 1987 A Merkel cell tumor appeared on the left cheek of an 83‐year‐old female was reported. The tumor was located mainly in the dermis and infiltrated to the subcutaneous adipose tissue with an involvement of the blood vessels and lymphatics at the periphery.
M, Kitazawa +5 more
openaire +3 more sources
, 2003 Merkel cells constitute a unique population that remains difficult to characterize in human skin because of their scarcity. Our aim was to develop tools for the study of Merkel cells in vitro.
Alphonse Roy +17 more
core +1 more source
The Touch Dome Defines an Epidermal Niche Specialized for Mechanosensory Signaling
Cell Reports, 2013 In mammalian skin, Merkel cells are mechanoreceptor cells that are required for the perception of gentle touch. Recent evidence indicates that mature Merkel cells descend from the proliferative layer of skin epidermis; however, the stem cell niche for ...
Yanne S. Doucet +3 more
doaj +1 more source
Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model. [PDF]
PLoS ONE, 2015 Merkel cell polyomavirus (MCV) causes the majority of human Merkel cell carcinomas (MCC) and encodes a small T (sT) antigen that transforms immortalized rodent fibroblasts in vitro. To develop a mouse model for MCV sT-induced carcinogenesis, we generated
Masahiro Shuda +10 more
doaj +1 more source
Merkel Cells in Somatosensation [PDF]
Chemosensory Perception, 2008 Merkel cells are rare epidermal cells whose function in the skin is still debated. These cells localize to highly touch-sensitive areas of vertebrate epithelia, including palatine ridges, touch domes and finger tips. In most cases, Merkel cells complex with somatosensory afferents to form slowly adapting touch receptors; it is unclear, however, whether
Henry, Haeberle, Ellen A, Lumpkin
openaire +2 more sources
Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Arthritis Care &Research, EarlyView.Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source
PLoS ONE, 2019 Engineered skin substitutes (ESS), prepared using primary human fibroblasts and keratinocytes with a biopolymer scaffold, were shown to provide stable closure of excised burns, but relatively little is known about innervation of ESS after grafting.
Jennifer M Hahn +5 more
doaj +1 more source
Treatment and Outcome of Merkel Cell Carcinoma in A Single Center
Zhongliu Fangzhi Yanjiu, 2023 Objective To investigate the clinical features, treatment, and outcome characteristics of patients with Merkel cell carcinoma. Methods The clinical manifestations, laboratory tests, diagnosis and treatment, and follow-up data of six patients with Merkel ...
REN Mengwei, XUE Xuemin, LIU Peng
doaj +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
Advanced Materials, EarlyView.This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source
The Challenges of Crisis Response of the Franco-German Tandem after 2022
Сравнительная политикаThe escalation of the Ukrainian crisis in February 2022 marked a new series of challenges for all key actors in international relations, including the states of the European Union.
A. P. Sokolov
doaj +1 more source