Results 121 to 130 of about 89,290 (238)

Successful Rapid Desensitization to Ceftazidime/Avibactam in a Patient With Cystic Fibrosis and Multidrug‐Resistant Pseudomonas aeruginosa Pneumonia: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Ceftazidime/avibactam (CAZ‐AVI) is an important therapeutic option for multidrug‐resistant (MDR) Pseudomonas aeruginosa infections; however, hypersensitivity reactions may preclude its use and create significant therapeutic challenges. We report a 21‐year‐old woman with cystic fibrosis and recurrent MDR P.
Zuoren Zhou, Jinqi Zhu, Ge Wu, Xi Kang, Qing Wang, Jie Liu, Yan Jiang   +6 more
wiley   +1 more source

Prevalence of on time administration of carbapenem and its impact on PK/PD target attainment in hospitalized patients: a multicenter retrospective study

Frontiers in Cellular and Infection Microbiology
ObjectiveOn time administration of carbapenem is important, but there are few data concerning the prevalence of timeliness and its impact on pharmacokinetic/pharmacodynamic (PK/PD) target achievement in hospitalized patients.MethodsThis was a multicenter
Jin Song, Xiaoping Pang, Huadong Chen, Ping Zhang, Miaofa Ying, Renai Xu, Zhenwei Yu, Zhenwei Yu   +7 more
doaj   +1 more source

Paratesticular Embryonal Rhabdomyosarcoma Masquerading as Epididymitis: A Diagnostic Challenge in Adolescents

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Paratesticular rhabdomyosarcoma is a rare malignancy in children and adolescents that frequently presents diagnostic challenges when mimicking benign inflammatory conditions. We report the case of a 14‐year‐old previously healthy male who presented with acute right scrotal pain and swelling initially diagnosed as epididymo‐orchitis.
Saif Khaled Abdalhadi Azzam, Lina Barhoum Barhoum, Ammir Abuzahra, Alaa Alazzeh, Khader Hassouneh, Nour Aldin K. Fakhory, Mohd Othman Lafi, M. I. Jawabreh Issa, Ibrahim Alzatari, Hamza Zughaier   +9 more
wiley   +1 more source

Meropenem.

Indian pediatrics, 2006
Meropenem is a new carbapenem antibacterial agent with wide spectrum of activity against gram-negative, gram-positive and anaerobic organisms. It is stable against most beta-lactamases produced by gram-negative bacteria and has greatest utility in treating severe infections in hospitalized children. It has good CSF penetrability and useful in treatment
Dheeraj, Shah, Manish, Narang
openaire   +1 more source

Combination of Oral Doxycycline and Rifampin for Pan‐Drug Resistant Klebsiella pneumoniae Infection: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Pan‐drug resistant Klebsiella pneumoniae is a major therapeutic challenge, particularly when standard last‐line agents are unavailable or contraindicated. We report a 45‐year‐old man with multifocal osteomyelitis and persistent purulent wound discharge despite broad‐spectrum antibiotics, repeated debridement, and two sequential amputations ...
Ali Akbar Heydari, Sepideh Elyasi, Farshad Abedi   +2 more
wiley   +1 more source

A Case of Tubo-ovarian Abscess due to Salmonella enterica Following an In Vitro Fertilization Attempt

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2019
Yusuf YAKUPOĞULLARI, Burak IŞIK, Nafia Canan GÜRSOY, Yaşar BAYINDIR, Barış OTLU   +4 more
doaj   +1 more source

Refractory Relapsing–Remitting Adult‐Onset Still's Disease in an Adolescent Female: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Adult‐onset Still's disease (AOSD) is a rare systemic autoinflammatory condition that presents with symptoms such as episodic fevers, a transient rash, inflammatory arthritis, and significant systemic inflammation. Diseases that have a relapsing–remitting clinical course can be challenging to diagnose and treat. We present a case of an 18 year
Tasnim Nafian, Mohd. Mujtaba Akib Bhuiyan, Kazi Ali Aftab, Khaled Mahbub Murshed, Md. Abul Kalam Azad   +4 more
wiley   +1 more source

Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba, Jubilee Andrew, Donald Fernandes   +2 more
wiley   +1 more source

Corticosteroids for Haemophagocytic Lymphohistiocytosis Secondary to Typhoid Fever: A Case Report

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Unlike haemophagocytic lymphohistiocytosis (HLH) induced by tuberculosis or rickettsial disease, there is no consensus for the treatment of HLH secondary to typhoid fever (Salmonella Typhi). After a short illustrative example, we searched among the previously described cases of HLH secondary to typhoid fever to determine: (i) Is the specific ...
Sonia Baumard, Aurélie Brunet, Isabelle Quatresous, Claire Pluchart, Yohan N'Guyen   +4 more
wiley   +1 more source

Emergence of Ceftazidime‐Avibactam‐Induced KPC Variants (KPC‐25/127) in Intracranial Infection and Implications for Clinical Management

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Novel KPC‐25 and first‐reported KPC‐127 sequentially evolved in one patient under CAZ‐AVI pressure, distinct mutations remodel enzyme activity to drive differential multidrug resistance. ABSTRACT The emergence of novel Klebsiella pneumoniae carbapenemase (KPC) variants contributing to clinical treatment failure poses a substantial threat to public ...
Ke Lei, Ying Tian, Chaoliang Xiong, Jing Lei, Dong Chen, Xiangni Bai, Mohd H. Abdul‐Aziz, Jiao Xie, Zeshi Liu   +8 more
wiley   +1 more source