Results 121 to 130 of about 78,101 (219)

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang   +19 more
wiley   +1 more source

Insights into the Thermal Degradation Kinetics of β-Lactam Antibiotics: A Comparative Study of Cefazolin, Ceftriaxone, and Meropenem

open access: yesAntibiotics
Background/Objectives: The thermal stability and degradation kinetics of β-lactam antibiotics are critical for understanding their behavior under processing and storage conditions.
Ovidiu Ghirlea   +9 more
doaj   +1 more source

Antibacterial and Antibiofilm Activity of a Chemically Characterized Cinnamomum verum Bark Methanolic Extract Against Multidrug‐Resistant Bacteria: Preliminary Antibiotic–Interaction Screening and Exploratory Molecular Docking

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The methanolic extract of Cinnamomum verum exhibited antibacterial and antibiofilm activities, enhanced the efficacy of conventional antibiotics against multidrug‐resistant bacteria, and showed favorable interactions with key bacterial targets in molecular docking analyses, supporting its potential as a natural antimicrobial adjuvant for combating ...
Hayet Edziri   +11 more
wiley   +1 more source

Severe Multiorgan Failure Triggered by Infection in an Adult With Decades of Untreated Sickle Cell Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 67‐year‐old man with decades of untreated sickle cell disease developed septic shock with multiorgan failure, splenic infarction, and marrow fibrosis; his genotype could not be confirmed. He recovered with intensive supportive care, with hydroxyurea initiated for long‐term disease modification, illustrating catastrophic infection‐triggered ...
Sara Shahidi, Gisha Mohan
wiley   +1 more source

A Case of Tubo-ovarian Abscess due to Salmonella enterica Following an In Vitro Fertilization Attempt

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2019
Yusuf YAKUPOĞULLARI   +4 more
doaj   +1 more source

Vasopressor‐Associated Limb Ischemia Resulting in Quadruple Amputation in Suspected Septic Shock

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Vasopressor‐associated limb ischemia (VALI) is a rare but devastating complication of vasopressor therapy in septic shock. This case shows catastrophic four‐limb amputation in a 26‐year‐old obese male with suspected septic shock. This case illustrates the complex interplay between prolonged high‐dose vasopressor therapy, morbid obesity, and ...
Muni Rubens   +8 more
wiley   +1 more source

A Rare Finding of Retroperitoneal Sepsis Following Robot‐Assisted Transanal Minimally Invasive Surgery (TAMIS): A Case Report and Review of the Literature

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Robot‐assisted transanal minimally invasive surgery (TAMIS) is a safe and effective platform for the local excision of early rectal lesions. While postoperative complications such as bleeding or contained perforation are recognized, rapidly progressive retroperitoneal sepsis remains an exceedingly rare occurrence.
Jonathan Tiong   +4 more
wiley   +1 more source

Extended Inflammatory Osteitis Pubis With Associated Myositis and Femoral Neuropathy in an Amateur Football Player: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 42‐year‐old male amateur football player presented with a 17‐day history of progressive groin pain, primarily on the right, radiating to the perineum, associated with limitation of hip motion. Because of proximal weakness and elevated inflammatory markers, polymyositis and an infectious process were initially suspected.
Sousan Kolahi   +4 more
wiley   +1 more source

Meropenem compared with ceftazidime in the empiric treatment of acute severe infections in hospitalized children. Italian Pediatric Meropenem Study Group

open access: yes, 1998
In a multicenter, randomized, open comparison of meropenem to ceftazidime as empiric treatment of severe acute infections, 185 children (1 mo-15 years old, mean 65.4 mo) were enrolled. Meropenem (20 mg/kg t.i.d.
P. Marchisio, N. Principi
core   +2 more sources

Volumetric Microsampling for Patient‐Centric Therapeutic Drug Monitoring in Clinical Pharmacology: A Scoping Review

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract Accurate drug concentration measurement is essential for precision pharmacotherapy, but conventional therapeutic drug monitoring (TDM) requires venous sampling, increasing patient burden, and potentially limiting participation in TDM and model‐informed precision dosing (MIPD).
Hari Prabhath Tummala   +5 more
wiley   +1 more source

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