Results 141 to 150 of about 100,222 (232)

Zwitterionic Penicillin‐Derived Sulfone Inhibitor for Combating β‐Lactamase‐Mediated Antibiotic Resistance

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
Combining enhanced permeability strategies with (2‐pyridyl)methylene substitution in the sulbactam scaffold led to a novel β‐lactamase inhibitor to combat β‐lactamase‐mediated resistance to β‐lactam antibiotics. The studies presented highlight the potential of compound 3 as a next‐generation β‐lactamase inhibitor for combating infections caused by ...
Diana Rodríguez, Emilio Lence, Juan C. Vázquez‐Ucha, Alejandro Beceiro, Concepción González‐Bello   +4 more
wiley   +1 more source

Double-carbapenem regimen, alone or in combination with colistin, in the treatment of infections caused by carbapenem-resistant Klebsiella pneumoniae (CR-Kp) [PDF]

, 2017
Aloj, F., Castaldi, D., D'Abramo, A., De Angelis, M., Gizzi, F., Mascellino, M. T., Mastroianni, C. M., Oliva, Alessandra, Scorzolini, L., Storto, M., Vullo, V.   +10 more
core   +1 more source

Pharmacokinetic analysis of nacubactam, a novel β-lactamase inhibitor, co-administered with meropenem in patients with a complicated urinary tract infection. [PDF]

JAC Antimicrob Resist
Morita J, Ishiwata K, Matsumoto S, Kato S, Attley G, Patel K, Rodriguez I, Mallalieu N.   +7 more
europepmc   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

In Vitro Evaluation of the Compatibility of Meropenem and Tanreqing Under Parallel Infusion Conditions. [PDF]

Pharmaceutics
Ren X, Li X, Dong Z.
europepmc   +1 more source

Investigating the Effect of Xylitol on <i>ompK36</i> Overexpression, Increased Meropenem Susceptibility, and Antibiofilm Activity in a Carbapenem-Resistant Clinical Strain of <i>Klebsiella pneumoniae</i>. [PDF]

Int J Microbiol
Ahlelyorof O, Flanagan J, Jabalameli F, Beigverdi R, Siroosi M.   +4 more
europepmc   +1 more source

Evidence of intrapulmonary penetration of nacubactam, a novel β-lactamase inhibitor, following coadministration of nacubactam with meropenem in healthy adults. [PDF]

Antimicrob Agents Chemother
Morita J, Ishiwata K, Matsumoto S, Kato S, Attley G, Patel K, Rodriguez I, Mallalieu NL.   +7 more
europepmc   +1 more source

Empiric antibiotics for sepsis [PDF]

, 2018
Buckman, Sara A, Mazuski, John E, Turnbull, Isaiah R   +2 more
core   +2 more sources

Extended vs Intermittent Infusion of Meropenem with Colistimethate Sodium and Risk of Acute Kidney Injury in Critically Ill Patients: A Propensity Score-Matched Retrospective Cohort Study. [PDF]

Infect Drug Resist
Hu Q, Wang H.
europepmc   +1 more source

Likelihood of aggressive PK/PD target attainment of continuous-infusion beta-lactams during the first week of treatment of febrile neutropenia: findings from a 1-year prospective, monocentric study in onco-haematological patients. [PDF]

J Antimicrob Chemother
Cojutti PG, Toschi A, Pasquini Z, Paolini S, Maffini E, Bonifazi F, Zinzani PL, Giannella M, Viale P, Pea F.   +9 more
europepmc   +1 more source