Meropenem-Vaborbactam (M-V) Compared With Piperacillin-Tazobactam (P-T) in the Treatment of Adults With Complicated Urinary Tract Infections (cUTI), Including Acute Pyelonephritis (AP) in a Phase 3 Randomized, Double-Blind, Double-Dummy Trial (TANGO 1) [PDF]
, 2016 Jeff Loutit +7 more
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Periprostatic Abscess Extending to the Perineum Following Hydrogel Spacer Placement: A Case Report
IJU Case Reports, Volume 9, Issue 1, January 2026.ABSTRACT Introduction Hydrogel spacers are commonly used to minimize rectal toxicity during prostate cancer radiotherapy. We report a case of a periprostatic abscess extending to the perineum following hydrogel spacer placement. Case Presentation A 59‐year‐old man diagnosed with prostate cancer (serum prostate–specific antigen level, 6.71 ng/mL ...
Daichi Hirata +8 more
wiley +1 more source
Determination of MIC and Disk Diffusion Quality Control Guidelines for Meropenem–Vaborbactam, a Novel Carbapenem/Boronic Acid β-Lactamase Inhibitor Combination [PDF]
, 2018 Meropenem–vaborbactam is a carbapenem/cyclic boronic acid β-lactamase inhibitor combination primarily active against Gram-negative bacilli, including those harboring class A serine carbapenemases such as Klebsiella pneumoniae carbapenemase (KPC).
Castanheira, Mariana +4 more
core +1 more source
The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.Abstract We previously developed a population pharmacokinetic (PopPK) model for meropenem in pediatric intensive care unit patients accounting for effect of body size, maturation, and kidney function on clearance. This study aimed to extrapolate meropenem exposure to neonates and young infants using the pediatric PopPK model and to validate the ...
Ronaldo Morales Junior +4 more
wiley +1 more source
1580. Colistin Potentiates the In Vitro Activity of Meropenem–Vaborbactam (M/V) Against Some, but not All KPC-producing Klebsiella pneumoniae (KPC-Kp) [PDF]
, 2019 Chelsea E Jones +4 more
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Respirology Case Reports, Volume 14, Issue 1, January 2026.This case illustrates features of ground glass changes on radiology in a patient who was immunosuppressed with biologics. Microbiology confirmed infection with Bordetella bronchiseptica, highlighting the importance of looking for atypical infections in patients receiving biologics and the importance of pet ownership history.
Debashree Banerjee +5 more
wiley +1 more source
Evolution of Resistant Mutants in Pseudomonas aeruginosa Persister Cells Under Meropenem Treatment
MicroorganismsBacterial persisters are dormant cells that survive antibiotic treatment, serving as a reservoir for the emergence of resistant mutations. The evolution of antibiotic resistance poses a significant challenge to public health.
Jie Feng +6 more
doaj +1 more source
Respirology Case Reports, Volume 14, Issue 1, January 2026.We report a case of community‐acquired pneumonia. In this case, the blood culture was essential for detection of co‐infection of Streptococcus pneumoniae and Klebsiella variicola, which combination is first reported. ABSTRACT Community‐acquired pneumonia (CAP) remains a leading cause of morbidity and mortality.
Naoki Fujimoto +7 more
wiley +1 more source
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2019 Yusuf YAKUPOĞULLARI +4 more
doaj +1 more source
Intra- and Interspecies Conjugal Transfer of Plasmids in Gram-Negative Bacteria
BiomedicinesBackground/Objectives: Plasmid-mediated resistance is a significant mechanism that contributes to the gradual decrease in the efficacy of antibiotics from various classes, including carbapenems.
Julia R. Savelieva +2 more
doaj +1 more source