Results 91 to 100 of about 85,740 (261)

The evolutionary landscape and serotypic dynamics of avian infectious bronchitis virus from spike protein

iMetaOmics, EarlyView.
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang, Zongxi Han, Chuangchao Zou, Yihui Huang, Shiping Sun, Ouyang Peng, Usama Ashraf, Qiuping Xu, Yao Ge, Qixiang Kang, Xiuli Ma, Xinheng Zhang, Ye Zhao, Xin Yang, Hongning Wang, Guozhong Zhang, Qingmei Xie, Mang Shi, Yongsen Ruan, Min Liao, Shengwang Liu, Yongchang Cao   +21 more
wiley   +1 more source

To what extent are Arab pilgrims to Makkah aware of the middle east respiratory syndrome coronavirus and the precautions against it?

Journal of Family and Community Medicine, 2017
BACKGROUND: Approximately, 80% of the many cases of the Middle East respiratory syndrome coronavirus (MERS-CoV) confirmed worldwide were diagnosed in the Kingdom of Saudi Arabia (KSA).
Meshaal S Alotaibi, Abdulaziz M Alsubaie, Khaled A Almohaimede, Turki A Alotaibi, Omar A Alharbi, Abdulrahman F Aljadoa, Abdulaziz H Alhamad, Mazin Barry   +7 more
doaj   +1 more source

Direct Detection of Viruses Using Antibody‐Modified Gold Nanorods

Journal of Biophotonics, EarlyView.
Gold nanorods functionalized with pathogen‐specific antibodies can be used for the confirmatory detection of viruses via dynamic light scattering–based analysis of particle sizes. ABSTRACT Seasonal and sporadic viral infections put enormous burdens on global health and society. Although polymerase chain reaction (PCR) and other molecular approaches can
Axell Rodriguez, Yana Purvinsh, Aidan P. Holman, Dmitry Kurouski   +3 more
wiley   +1 more source

Deciphering MERS-CoV Evolution in Dromedary Camels [PDF]

Trends in Microbiology, 2016
The emergence of the Middle East respiratory syndrome coronavirus (MERS-CoV) poses a potential threat to global public health. Many aspects of the evolution and transmission of MERS-CoV in its animal reservoir remain unclear. A recent study provides new insights into the evolution and transmission of MERS-CoV in dromedary camels.
Du, Lin, Han, Guan-Zhu
openaire   +2 more sources

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Newcastle disease virus-based MERS-CoV candidate vaccine elicits high-level and lasting neutralizing antibodies in Bactrian camels

Journal of Integrative Agriculture, 2017
: Middle East respiratory syndrome coronavirus (MERS-CoV), a member of the Coronaviridae family, is the causative pathogen for MERS that is characterized by high fever, pneumonia, acute respiratory distress syndrome (ARDS), as well as extrapulmonary ...
Ren-qiang LIU, Jin-ying GE, Jin-ling WANG, Yu SHAO, Hui-lei ZHANG, Jin-liang WANG, Zhi-yuan WEN, Zhi-gao BU   +7 more
doaj   +1 more source

A fusion peptide in the spike protein of MERS coronavirus [PDF]

, 2019
Coronaviruses represent current and emerging threats for many species, including humans. Middle East respiratory syndrome-related coronavirus (MERS-CoV) is responsible for sporadic infections in mostly Middle Eastern countries, with occasional transfer ...
Benjamin W. Neuman, Earp, Entedar A. J. Alsaadi, Hu, Ian M. Jones   +4 more
core   +1 more source

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and COVID-19 infection during pregnancy [PDF]

, 2020
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A.
core   +1 more source

Pilgrims and MERS-CoV: what’s the risk? [PDF]

Emerging Themes in Epidemiology, 2015
The risk of Middle East Respiratory Syndrome Coronavirus spreading globally is worrying, given the annual mass gathering of the Hajj and the year-long influx of pilgrims undertaking the Umrah. Based on the incidence in Saudi Arabia since June 2012, the most likely scenario given recent pilgrim numbers is estimated to be one case per Hajj, and three ...
Soliman, Tarek, Cook, Alex R, Coker, Richard J   +2 more
openaire   +3 more sources

Near‐complete genome assembly of a transformation‐efficient elite inbred line LH244 and its comparison with B73

Journal of Integrative Plant Biology, EarlyView.
Analysis of a near‐complete assembly of the genome of the highly transformable maize inbred line LH244 revealed its high genetic similarity to B73 and will serve as a much‐needed resource for functional genomics and genome editing of maize. ABSTRACT The highly transformable maize inbred line LH244 represents an attractive model for gene discovery and ...
Kaiwen Tan, Xinxiang Liu, Zijian Wang, Zhengquan Zhang, Wei Huang, Shengnan Liu, Zhen Lin, Haiming Zhao, Hainan Zhao, Yang Liu, Fangpu Han, Jinsheng Lai, Weibin Song, Jiuran Zhao, Jian Chen   +14 more
wiley   +1 more source