Results 31 to 40 of about 60,311 (178)

Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection

mBio, 2020
Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe and fatal acute respiratory disease in humans and remains endemic in the Middle East since first being identified in 2012.
Kun Li, Zhuo Li, Christine Wohlford-Lenane, David K. Meyerholz, Rudragouda Channappanavar, Dong An, Stanley Perlman, Paul B. McCray, Biao He   +8 more
doaj   +1 more source

Monoclonal antibodies constructed from COVID-19 convalescent memory B cells exhibit potent binding activity to MERS-CoV spike S2 subunit and other human coronaviruses

Frontiers in Immunology, 2022
IntroductionThe Middle East respiratory syndrome coronavirus (MERS-CoV) and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are two highly contagious coronaviruses causing MERS and COVID-19, respectively, without an effective antiviral ...
Yuan Peng, Yuan Peng, Yongcheng Liu, Yabin Hu, Fangfang Chang, Qian Wu, Qian Wu, Jing Yang, Jun Chen, Shishan Teng, Jian Zhang, Rongzhang He, Youchuan Wei, Mihnea Bostina, Tingrong Luo, Wenpei Liu, Xiaowang Qu, Yi-Ping Li, Yi-Ping Li   +18 more
doaj   +1 more source

Evaluation of visual triage for screening of Middle East respiratory syndrome coronavirus patients

New Microbes and New Infections, 2018
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in September 2012 in Saudi Arabia had attracted the attention of the global health community.
S.H. Alfaraj, J.A. Al-Tawfiq, P. Gautret, M.G. Alenazi, A.Y. Asiri, Z.A. Memish   +5 more
doaj   +1 more source

Cross-sectional study of MERS-CoV-specific RNA and antibodies in animals that have had contact with MERS patients in Saudi Arabia

Journal of Infection and Public Health, 2018
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly emerged coronavirus that is associated with a severe respiratory disease in humans in the Middle East. The epidemiological profiles of the MERS-CoV infections suggest zoonotic
Samy Kasem, Ibraheem Qasim, Ali Al-Hufofi, Osman Hashim, Ali Alkarar, Ali Abu-Obeida, Albagir Gaafer, Abdelhamid Elfadil, Ahmed Zaki, Ahmed Al-Romaihi, Nasereldeen Babekr, Nadr El-Harby, Raed Hussien, Ali AL-Sahaf, Ali Al-Doweriej, Faisal Bayoumi, Leo L.M. Poon, Daniel K.W. Chu, Malik Peiris, Ranawaka A.P.M. Perera   +19 more
doaj   +1 more source

Middle East Respiratory Syndrome Coronavirus Antibodies in Bactrian and Hybrid Camels from Dubai

mSphere, 2020
So far, dromedary camels are the only known animal reservoir for Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV). Previous published serological studies showed that sera of Bactrian camels were all negative for MERS-CoV antibodies. However,
Susanna K. P. Lau, Kenneth S. M. Li, Hayes K. H. Luk, Zirong He, Jade L. L. Teng, Kwok-Yung Yuen, Ulrich Wernery, Patrick C. Y. Woo   +7 more
doaj   +1 more source

Potential Cross-Reactive Immunity to COVID-19 Infection in Individuals With Laboratory-Confirmed MERS-CoV Infection: A National Retrospective Cohort Study From Saudi Arabia

Frontiers in Immunology, 2021
BackgroundA growing number of experiments have suggested potential cross-reactive immunity between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and previous human coronaviruses.
Anas A. Khan, Anas A. Khan, Ahmed A. Alahmari, Yasir Almuzaini, Fahad Alamri, Yousef Mohammad Alsofayan, Alhanouf Aburas, Saleh Al-Muhsen, Maria Van Kerkhove, Saber Yezli, Gregory R. Ciottone, Abdullah M. Assiri, Hani A. Jokhdar   +12 more
doaj   +1 more source

Molecular Characteristics, Functions, and Related Pathogenicity of MERS-CoV Proteins

Engineering, 2019
Middle East respiratory syndrome (MERS) is a viral respiratory disease caused by a de novo coronavirus—MERS-CoV—that is associated with high mortality. However, the mechanism by which MERS-CoV infects humans remains unclear.
Yan-Hua Li, Chen-Yu Hu, Nan-Ping Wu, Hang-Ping Yao, Lan-Juan Li   +4 more
doaj   +1 more source

MERS-CoV diagnosis: An update

Journal of Infection and Public Health, 2016
Diagnosis of MERS-Cov still a major concern in most of daignostic laboratories. To date the Real-time Polymerase Chain reaction (RT-PCR) is the mainstay for diagnosis of MERS-CoV. RT-PCR has limitations, including a long turnaround time and lack of common measurements and correlations with Viral Load (VL). It is recommended to screen for MERS-CoV using
Sameera Al Johani, Ali H. Hajeer
openaire   +3 more sources

Assessing the pandemic potential of MERS-CoV [PDF]

The Lancet, 2013
The final publication is available at Elsevier via http://dx.doi.org/10.1016/S0140-6736(13)61504-4 © 2013. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
Bauch, Chris T, Oraby, Tamer
openaire   +2 more sources

Anti-S1 MERS-COV IgY Specific Antibodies Decreases Lung Inflammation and Viral Antigen Positive Cells in the Human Transgenic Mouse Model

Vaccines, 2020
The Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in 2012 and causes severe and often fatal acute respiratory illness in humans. No approved prophylactic and therapeutic interventions are currently available.
Aymn T. Abbas, Sherif A. El-Kafrawy, Sayed Sartaj Sohrab, Ashraf A. Tabll, Ahmed M. Hassan, Naoko Iwata-Yoshikawa, Noriyo Nagata, Esam I. Azhar   +7 more
doaj   +1 more source