Results 31 to 40 of about 59,724 (178)

Molecular Characteristics, Functions, and Related Pathogenicity of MERS-CoV Proteins

Engineering, 2019
Middle East respiratory syndrome (MERS) is a viral respiratory disease caused by a de novo coronavirus—MERS-CoV—that is associated with high mortality. However, the mechanism by which MERS-CoV infects humans remains unclear.
Yan-Hua Li, Chen-Yu Hu, Nan-Ping Wu, Hang-Ping Yao, Lan-Juan Li   +4 more
doaj   +1 more source

Anti-S1 MERS-COV IgY Specific Antibodies Decreases Lung Inflammation and Viral Antigen Positive Cells in the Human Transgenic Mouse Model

Vaccines, 2020
The Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in 2012 and causes severe and often fatal acute respiratory illness in humans. No approved prophylactic and therapeutic interventions are currently available.
Aymn T. Abbas, Sherif A. El-Kafrawy, Sayed Sartaj Sohrab, Ashraf A. Tabll, Ahmed M. Hassan, Naoko Iwata-Yoshikawa, Noriyo Nagata, Esam I. Azhar   +7 more
doaj   +1 more source

Middle East respiratory syndrome coronavirus—a 10-year (2012-2022) global analysis of human and camel infections, genomic sequences, lineages, and geographical origins

International Journal of Infectious Diseases, 2023
Objectives: The World Health Organization priority zoonotic pathogen Middle East respiratory syndrome (MERS) coronavirus (CoV) has a high case fatality rate in humans and circulates in camels worldwide.
Esam I. Azhar, Thirumalaisamy P. Velavan, Ikrormi Rungsung, Tieble Traore, David S. Hui, Brian McCloskey, Sherif A. El-Kafrawy, Alimuddin Zumla   +7 more
doaj   +1 more source

Prospects for a MERS-CoV spike vaccine [PDF]

Expert Review of Vaccines, 2018
Six years have passed since Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV), a newly emerging infectious virus, was first reported in 2012. Although MERS-CoV has had a consistently high mortality rate in humans, no vaccines have been approved to prevent MERS-CoV infection in humans.
Yusen Zhou, Shibo Jiang, Lanying Du
openaire   +3 more sources

Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins

Emerging Microbes and Infections, 2018
Previous findings of Middle East Respiratory Syndrome coronavirus (MERS-CoV)-related viruses in bats, and the ability of Tylonycteris-BatCoV HKU4 spike protein to utilize MERS-CoV receptor, human dipeptidyl peptidase 4 hDPP4, suggest a bat ancestral ...
Susanna K. P. Lau, Rachel Y. Y. Fan, Hayes K. H. Luk, Longchao Zhu, Joshua Fung, Kenneth S. M. Li, Emily Y. M. Wong, Syed Shakeel Ahmed, Jasper F. W. Chan, Raven K. H. Kok, Kwok-Hung Chan, Ulrich Wernery, Kwok-Yung Yuen, Patrick C. Y. Woo   +13 more
doaj   +1 more source

Virtual Screening and Inhibition of Middle East Respiratory Syndrome Coronavirus Replication by Targeting Papain-like Protease

Dr. Sulaiman Al Habib Medical Journal, 2021
Infection by the emerging, potentially zoonotic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) presents a severe health hazard to humans and is often fatal.
Mahmoud Kandeel, Byoung Kwon Park, Mohamed A. Morsy, Katharigatta N. Venugopala, Kentaro Oh-hashi, Mohammed Al-Nazawi, Hyung-Joo Kwon   +6 more
doaj   +1 more source

CD8+ T Cells Responding to the Middle East Respiratory Syndrome Coronavirus Nucleocapsid Protein Delivered by Vaccinia Virus MVA in Mice

Viruses, 2018
Middle East respiratory syndrome coronavirus (MERS-CoV), a novel infectious agent causing severe respiratory disease and death in humans, was first described in 2012.
Svenja Veit, Sylvia Jany, Robert Fux, Gerd Sutter, Asisa Volz   +4 more
doaj   +1 more source

MERS-CoV [PDF]

Oman Medical Journal, 2014
Beuy Joob, Viroj Wiwanitkit
  +8 more sources

Scanning Electron Microscopic Findings on Respiratory Organs of Some Naturally Infected Dromedary Camels with the Lineage-B of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Saudi Arabia—2018

Pathogens, 2021
The currently known animal reservoir for MERS-CoV is the dromedary camel. The clinical pattern of the MERS-CoV field infection in dromedary camels is not yet fully studied well.
Abdelmohsen Alnaeem, Samy Kasem, Ibrahim Qasim, Mohamed Refaat, Ali Nasser Alhufufi, Ali Al-Doweriej, Abdulkareem Al-Shabebi, Abd-El Rahman Taha Hereba, Maged Gomaa Hemida   +8 more
doaj   +1 more source

Drivers of MERS-CoV Emergence in Qatar [PDF]

Viruses, 2018
MERS-CoV (Middle East respiratory syndrome corona virus) antibodies were detected in camels since 1983, but the first human case was only detected in 2012. This study sought to identify and quantify possible drivers for the MERS-CoV emergence and spillover to humans. A list of potential human, animal and environmental drivers for disease emergence were
Elmoubasher Farag, Reina S. Sikkema, Tinka Vinks, Md Mazharul Islam, Mohamed Nour, Hamad Al-Romaihi, Mohammed Al Thani, Muzzamil Atta, Farhoud H. Alhajri, Salih Al-Marri, Mohd AlHajri, Chantal Reusken, Marion Koopmans   +12 more
openaire   +4 more sources