Results 31 to 40 of about 252,954 (227)

Knowledge and practices of primary health care physicians regarding updated guidelines of MERS-CoV infection in Abha city

Journal of Family Medicine and Primary Care, 2019
Background: Human coronaviruses (hCoV) usually cause mild to moderate upper respiratory tract illnesses. The novel coronavirus (nCoV), or Middle East respiratory syndrome coronavirus (MERS-CoV), is a particular strain different from any other known hCoV ...
Saad Al-Amri, Rishi Bharti, Safar A Alsaleem, Hassan M Al-Musa, Shweta Chaudhary, Ayub A Al-Shaikh   +5 more
doaj   +1 more source

Unraveling the drivers of MERS-CoV transmission [PDF]

Proceedings of the National Academy of Sciences, 2016
Significance Since it was discovered in 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) has infected more than 1,700 persons, one-third of whom died, essentially in the Middle East. Persons can get infected by direct or indirect contact with dromedary camels, and although human-to-human transmission is not self-sustaining in the
Simon Cauchemez, Pierre Nouvellet, Anne Cori, Thibaut Jombart, Tini Garske, Hannah Clapham, Sean Moore, Harriet Linden Mills, Henrik Salje, Caitlin Collins, Isabel Rodriquez-Barraquer, Steven Riley, Shaun Truelove, Homoud Algarni, Rafat Alhakeem, Khalid AlHarbi, Abdulhafiz Turkistani, Ricardo J. Aguas, Derek A. T. Cummings, Maria D. Van Kerkhove, Christl A. Donnelly, Justin Lessler, Christophe Fraser, Ali Al-Barrak, Neil M. Ferguson   +24 more
openaire   +4 more sources

Comparing the Immunogenicity and Protective Effects of Three MERS-CoV Inactivation Methods in Mice

Vaccines, 2022
The Middle East respiratory syndrome (MERS) is a fatal acute viral respiratory disease caused by MERS-coronavirus (MERS-CoV) infection. To date, no vaccine has been approved for MERS-CoV despite continuing outbreaks.
Nayoung Kim, Tae-Young Lee, Hansaem Lee, Jeong-Sun Yang, Kyung-Chang Kim, Joo-Yeon Lee, Hyun-Joo Kim   +6 more
doaj   +1 more source

MERS-CoV and HCoV-229E genome-wide CRISPR/Cas-9–mediated KO screens.

, 2021
(A) Native Huh7 cells were transduced with the GeCKOv2 lentiviral genome-wide CRISPR library, ensuring a coverage of approximately 500 cells per sgRNA. Transduced cells were selected and then infected with either MERS-CoV or HCoV-229E at indicated MOIs ...
Jenna N. Kelly (10492462), Philippe Plattet (330823), Neeta Shrestha (11883857), Ronald Dijkman (330307), Albrecht von Brunn (29223), Annika Kratzel (10492471), Gert Zimmer (223023), Jasmine Portmann (4053757), Stephanie Pfaender (2868038), Philip V’kovski (3716905), Yannick Brüggemann (11883854), Daniel Todt (777446), Eike Steinmann (32663), Volker Thiel (78076), Claudia A. Staab-Weijnitz (5326895), Nadine Ebert (10492480)   +15 more
core   +1 more source

MERS-CoV diagnosis: An update

Journal of Infection and Public Health, 2016
Diagnosis of MERS-Cov still a major concern in most of daignostic laboratories. To date the Real-time Polymerase Chain reaction (RT-PCR) is the mainstay for diagnosis of MERS-CoV. RT-PCR has limitations, including a long turnaround time and lack of common measurements and correlations with Viral Load (VL). It is recommended to screen for MERS-CoV using
Sameera Al Johani, Ali H. Hajeer
openaire   +3 more sources

Innate immune response to MERS-CoV-MA-Δ4b in mice.

, 2022
hDPP4-KI mice were infected with 5x104 PFU of MERS-CoV-MA-WT, MERS-CoV-MA-Δ4b or MERS-CoV-MA-mNLS virus. Mice were sacrificed at 4 and 6 dpi and the RNA of the lungs was extracted for gene expression assays. mRNA expression levels of genes related to the
Isabel Sola (218107), Ricardo Requena-Platek (13839769), Jesús Hurtado-Tamayo (13839766), Melissa Bello-Perez (6239639), Javier Canton (3254541), Pedro José Sánchez-Cordón (13839772), Luis Enjuanes (146937), Raúl Fernandez-Delgado (4798362)   +7 more
core   +1 more source

Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection

mBio, 2020
Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe and fatal acute respiratory disease in humans and remains endemic in the Middle East since first being identified in 2012.
Kun Li, Zhuo Li, Christine Wohlford-Lenane, David K. Meyerholz, Rudragouda Channappanavar, Dong An, Stanley Perlman, Paul B. McCray, Biao He   +8 more
doaj   +1 more source

Monoclonal antibodies constructed from COVID-19 convalescent memory B cells exhibit potent binding activity to MERS-CoV spike S2 subunit and other human coronaviruses

Frontiers in Immunology, 2022
IntroductionThe Middle East respiratory syndrome coronavirus (MERS-CoV) and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are two highly contagious coronaviruses causing MERS and COVID-19, respectively, without an effective antiviral ...
Yuan Peng, Yuan Peng, Yongcheng Liu, Yabin Hu, Fangfang Chang, Qian Wu, Qian Wu, Jing Yang, Jun Chen, Shishan Teng, Jian Zhang, Rongzhang He, Youchuan Wei, Mihnea Bostina, Tingrong Luo, Wenpei Liu, Xiaowang Qu, Yi-Ping Li, Yi-Ping Li   +18 more
doaj   +1 more source

Evaluation of visual triage for screening of Middle East respiratory syndrome coronavirus patients

New Microbes and New Infections, 2018
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in September 2012 in Saudi Arabia had attracted the attention of the global health community.
S.H. Alfaraj, J.A. Al-Tawfiq, P. Gautret, M.G. Alenazi, A.Y. Asiri, Z.A. Memish   +5 more
doaj   +1 more source

Protein Intrinsic Disorder and Evolvability of MERS-CoV [PDF]

Biomolecules, 2021
Middle East Respiratory Syndrome (MERS) is a viral respiratory disease caused by one of the human coronaviruses, MERS-CoV [...]
Vladimir N. Uversky, Elrashdy M. Redwan, Abdullah A. Aljadawi   +2 more
openaire   +4 more sources