Results 41 to 50 of about 27,602 (177)

Growth and Quantification of MERS‐CoV Infection [PDF]

Current Protocols in Microbiology, 2015
AbstractMiddle East respiratory syndrome coronavirus (MERS‐CoV) is an emerging highly pathogenic respiratory virus. Although MERS‐CoV only emerged in 2012, we and others have developed assays to grow and quantify infectious MERS‐CoV and RNA products of replication in vitro. MERS‐CoV is able to infect a range of cell types, but replicates to high titers
Coleman, Christopher M., Frieman, Matthew B.   +1 more
openaire   +2 more sources

Cross-sectional study of MERS-CoV-specific RNA and antibodies in animals that have had contact with MERS patients in Saudi Arabia

Journal of Infection and Public Health, 2018
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly emerged coronavirus that is associated with a severe respiratory disease in humans in the Middle East. The epidemiological profiles of the MERS-CoV infections suggest zoonotic
Samy Kasem, Ibraheem Qasim, Ali Al-Hufofi, Osman Hashim, Ali Alkarar, Ali Abu-Obeida, Albagir Gaafer, Abdelhamid Elfadil, Ahmed Zaki, Ahmed Al-Romaihi, Nasereldeen Babekr, Nadr El-Harby, Raed Hussien, Ali AL-Sahaf, Ali Al-Doweriej, Faisal Bayoumi, Leo L.M. Poon, Daniel K.W. Chu, Malik Peiris, Ranawaka A.P.M. Perera   +19 more
doaj   +1 more source

Middle East respiratory syndrome coronavirus in dromedary camels: An outbreak investigation [PDF]

, 2014
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe lower respiratory tract infection in people. Previous studies suggested dromedary camels were a reservoir for this virus.
Al Dhahiry, S.H.S. (Said), Al Khal, A. (Abdullatif), Al Romaihi, H.E. (Hamad), Al-Marri, S.A. (Salih), Al-Thani, M. (Mohamed), Alhajri, F. (Farhoud), AlHajri, M.M. (Mohd), Bermingham, A. (Alison), Diab, A. (Ayman), Farag, E. (Elmoubasher), Galiano, M. (Monica), Ghobashy, H. (Hazem), Godeke, G-J. (Gert-Jan), Haagmans, B.L. (Bart), Jonges, M. (Marcel), Koopmans D.V.M., M.P.G. (Marion), Myers, R.H. (Richard), Osterhaus, A.D.M.E. (Albert), Raj, V.S. (Stalin), Reusken, C.B.E.M. (Chantal)   +19 more
core   +1 more source

Molecular Characteristics, Functions, and Related Pathogenicity of MERS-CoV Proteins

Engineering, 2019
Middle East respiratory syndrome (MERS) is a viral respiratory disease caused by a de novo coronavirus—MERS-CoV—that is associated with high mortality. However, the mechanism by which MERS-CoV infects humans remains unclear.
Yan-Hua Li, Chen-Yu Hu, Nan-Ping Wu, Hang-Ping Yao, Lan-Juan Li   +4 more
doaj   +1 more source

The impact of co-infection of influenza A virus on the severity of Middle East Respiratory Syndrome Coronavirus [PDF]

, 2017
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Alfaraj, Sarah H., Altwaijri, Talal A., Alzahrani, Nojoom A., Memish, Ziad A.   +4 more
core   +1 more source

Anti-S1 MERS-COV IgY Specific Antibodies Decreases Lung Inflammation and Viral Antigen Positive Cells in the Human Transgenic Mouse Model

Vaccines, 2020
The Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in 2012 and causes severe and often fatal acute respiratory illness in humans. No approved prophylactic and therapeutic interventions are currently available.
Aymn T. Abbas, Sherif A. El-Kafrawy, Sayed Sartaj Sohrab, Ashraf A. Tabll, Ahmed M. Hassan, Naoko Iwata-Yoshikawa, Noriyo Nagata, Esam I. Azhar   +7 more
doaj   +1 more source

Middle East respiratory syndrome coronavirus—a 10-year (2012-2022) global analysis of human and camel infections, genomic sequences, lineages, and geographical origins

International Journal of Infectious Diseases, 2023
Objectives: The World Health Organization priority zoonotic pathogen Middle East respiratory syndrome (MERS) coronavirus (CoV) has a high case fatality rate in humans and circulates in camels worldwide.
Esam I. Azhar, Thirumalaisamy P. Velavan, Ikrormi Rungsung, Tieble Traore, David S. Hui, Brian McCloskey, Sherif A. El-Kafrawy, Alimuddin Zumla   +7 more
doaj   +1 more source

Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins

Emerging Microbes and Infections, 2018
Previous findings of Middle East Respiratory Syndrome coronavirus (MERS-CoV)-related viruses in bats, and the ability of Tylonycteris-BatCoV HKU4 spike protein to utilize MERS-CoV receptor, human dipeptidyl peptidase 4 hDPP4, suggest a bat ancestral ...
Susanna K. P. Lau, Rachel Y. Y. Fan, Hayes K. H. Luk, Longchao Zhu, Joshua Fung, Kenneth S. M. Li, Emily Y. M. Wong, Syed Shakeel Ahmed, Jasper F. W. Chan, Raven K. H. Kok, Kwok-Hung Chan, Ulrich Wernery, Kwok-Yung Yuen, Patrick C. Y. Woo   +13 more
doaj   +1 more source

Influenza is more common than Middle East Respiratory Syndrome Coronavirus (MERS-CoV) among hospitalized adult Saudi patients [PDF]

, 2017
Background Since the initial description of Middle East Respiratory Syndrome Coronavirus (MERS-CoV), we adopted a systematic process of screening patients admitted with community acquired pneumonia.
Al-Tawfiq, Jaffar A., Hinedi, Kareem, Rabaan, Ali A.   +2 more
core   +1 more source

Studying Evolutionary Adaptation of MERS-CoV [PDF]

, 2019
Forced viral adaptation is a powerful technique employed to study the ways viruses may overcome various selective pressures that reduce viral replication. Here, we describe methods for in vitro serial passaging of Middle East respiratory syndrome coronavirus (MERS-CoV) to select for mutations which increase replication on semi-permissive cell lines as ...
Letko, Michael, Munster, Vincent
openaire   +2 more sources