Results 21 to 30 of about 60,311 (178)

MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is Endemic [PDF]

Emerging Infectious Diseases, 2016
To the Editor: Accumulating evidence indicates that dromedaries (Camelus dromedarius) are a reservoir for zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Although numerous studies have looked at other livestock in the Middle East region, evidence for MERS-CoV infection has only been found in dromedaries (1).
Reusken, Chantal B.E.M., Schilp, Chrispijn, Raj, V. Stalin, De Bruin, Erwin, Kohl, Robert H.G., Farag, Elmoubasher A.B.A., Haagmans, Bart L., Al-Romaihi, Hamad, Le Grange, Francois, Bosch, Berend-Jan, Koopmans, Marion P.G.   +10 more
openaire   +4 more sources

A Comparative Study of Clinical Presentation and Risk Factors for Adverse Outcome in Patients Hospitalised with Acute Respiratory Disease Due to MERS Coronavirus or Other Causes. [PDF]

PLoS ONE, 2016
Middle East Respiratory syndrome (MERS) first emerged in Saudi Arabia in 2012 and remains a global health concern. The objective of this study was to compare the clinical features and risk factors for adverse outcome in patients with RT-PCR confirmed ...
Musa A Garbati, Shamsudeen F Fagbo, Vicky J Fang, Leila Skakni, Mercy Joseph, Tariq A Wani, Benjamin J Cowling, Malik Peiris, Ahmed Hakawi   +8 more
doaj   +1 more source

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus

Emerging Microbes and Infections, 2020
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) causes a severe respiratory disease in humans. The MERS-CoV spike (S) glycoprotein mediates viral entry into target cells.
Hannah Kleine-Weber, Simon Schroeder, Nadine Krüger, Alexander Prokscha, Hassan Y. Naim, Marcel A. Müller, Christian Drosten, Stefan Pöhlmann, Markus Hoffmann   +8 more
doaj   +1 more source

A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines. [PDF]

PLoS ONE, 2013
An emerging respiratory infectious disease with high mortality, Middle East respiratory syndrome (MERS), is caused by a novel coronavirus (MERS-CoV). It was first reported in 2012 in Saudi Arabia and has now spread to eight countries.
Lanying Du, Zhihua Kou, Cuiqing Ma, Xinrong Tao, Lili Wang, Guangyu Zhao, Yaoqing Chen, Fei Yu, Chien-Te K Tseng, Yusen Zhou, Shibo Jiang   +10 more
doaj   +1 more source

The medical and biochemical knowledge of health care professionals regarding the management of MERS-CoV: lessons from 2019 pilgrimage season in Al-Madinah, Saudi Arabia: A cross-sectional study

SVU - International Journal of Medical Sciences, 2023
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) epidemic was a serious healthcare concern not responding to conventional anti-viral therapies between 2012 and 2017 with high fatality rates.
Mariam Eid Alanzi, Mona Ali H. Albalawi , Saeed Kabrah, Yasmeen Talal Aljehani , Ahmed M. Okashah, Ayman M Yenbaawi, Sami Saleem Alrehaily , Areej Meshal Aljumaidi , Bandar Alkabli , Mohamed Hamed Almutairi , Riyadh Alghamdi, Manal Ali Alsharif , Zohoor Dahie Aljohani, Rehab Ismail H. Alribyawi , Sultan Ahmed H. Alluqmany , Ahlam Awad Aljohani , Suzan Talal Aljehani , Zain Jaber Alghamdi, Ahmad Mohsen Aljermaawi , Amir Gadhyan Aldebeesi , May Mohamed Almutairi, Khalid Eid Alanzi , Nusaybah Eid Alanzi , Saud Idris Umar , Fahad Majed Almutari, Hamza Bakeet Altorgmi, Osama Abdel-Mageed, Abdel-Raheem Donkol , Mohamed Abdel-Haleem, Hussam H. Baghdadi, Salah Mohamed El Sayed*   +30 more
doaj   +1 more source

Molecular aspects of MERS-CoV [PDF]

Frontiers of Medicine, 2017
Middle East respiratory syndrome coronavirus (MERS-CoV) is a betacoronavirus which can cause acute respiratory distress in humans and is associated with a relatively high mortality rate. Since it was first identified in a patient who died in a Jeddah hospital in 2012, the World Health Organization has been notified of 1735 laboratory-confirmed cases ...
Rabaan, Ali A., Bazzi, Ali M., Al-Ahmed, Shamsah H., Al-Tawfiq, Jaffar A.   +3 more
openaire   +2 more sources

Bactrian camels shed large quantities of Middle East respiratory syndrome coronavirus (MERS-CoV) after experimental infection

Emerging Microbes and Infections, 2019
In 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) emerged. To date, more than 2300 cases have been reported, with an approximate case fatality rate of 35%.
Danielle R. Adney, Michael Letko, Izabela K. Ragan, Dana Scott, Neeltje van Doremalen, Richard A. Bowen, Vincent J. Munster   +6 more
doaj   +1 more source

Growth and Quantification of MERS‐CoV Infection [PDF]

Current Protocols in Microbiology, 2015
AbstractMiddle East respiratory syndrome coronavirus (MERS‐CoV) is an emerging highly pathogenic respiratory virus. Although MERS‐CoV only emerged in 2012, we and others have developed assays to grow and quantify infectious MERS‐CoV and RNA products of replication in vitro. MERS‐CoV is able to infect a range of cell types, but replicates to high titers
Coleman, Christopher M., Frieman, Matthew B.   +1 more
openaire   +2 more sources

Knowledge and practices of primary health care physicians regarding updated guidelines of MERS-CoV infection in Abha city

Journal of Family Medicine and Primary Care, 2019
Background: Human coronaviruses (hCoV) usually cause mild to moderate upper respiratory tract illnesses. The novel coronavirus (nCoV), or Middle East respiratory syndrome coronavirus (MERS-CoV), is a particular strain different from any other known hCoV ...
Saad Al-Amri, Rishi Bharti, Safar A Alsaleem, Hassan M Al-Musa, Shweta Chaudhary, Ayub A Al-Shaikh   +5 more
doaj   +1 more source

Comparing the Immunogenicity and Protective Effects of Three MERS-CoV Inactivation Methods in Mice

Vaccines, 2022
The Middle East respiratory syndrome (MERS) is a fatal acute viral respiratory disease caused by MERS-coronavirus (MERS-CoV) infection. To date, no vaccine has been approved for MERS-CoV despite continuing outbreaks.
Nayoung Kim, Tae-Young Lee, Hansaem Lee, Jeong-Sun Yang, Kyung-Chang Kim, Joo-Yeon Lee, Hyun-Joo Kim   +6 more
doaj   +1 more source