Results 11 to 20 of about 59,724 (178)

Enhancing immune protection against MERS-CoV: the synergistic effect of proteolytic cleavage sites and the fusion peptide and RBD domain targeting VLP immunization

open access: yesFrontiers in Immunology, 2023
IntroductionThe Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic infectious virus that has caused significant outbreaks in the Middle East and beyond.
Jeein Oh   +11 more
doaj   +1 more source

Liposome-Mediated Delivery of MERS Antigen Induces Potent Humoral and Cell-Mediated Immune Response in Mice

open access: yesMolecules, 2022
The advancements in the field of nanotechnology have provided a great platform for the development of effective antiviral vaccines. Liposome-mediated delivery of antigens has been shown to induce the antigen-specific stimulation of the humoral and cell ...
Masood Alam Khan   +6 more
doaj   +1 more source

MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is Endemic [PDF]

open access: yesEmerging Infectious Diseases, 2016
To the Editor: Accumulating evidence indicates that dromedaries (Camelus dromedarius) are a reservoir for zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Although numerous studies have looked at other livestock in the Middle East region, evidence for MERS-CoV infection has only been found in dromedaries (1).
Reusken, Chantal B.E.M.   +10 more
openaire   +4 more sources

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus

open access: yesEmerging Microbes and Infections, 2020
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) causes a severe respiratory disease in humans. The MERS-CoV spike (S) glycoprotein mediates viral entry into target cells.
Hannah Kleine-Weber   +8 more
doaj   +1 more source

A Comparative Study of Clinical Presentation and Risk Factors for Adverse Outcome in Patients Hospitalised with Acute Respiratory Disease Due to MERS Coronavirus or Other Causes. [PDF]

open access: yesPLoS ONE, 2016
Middle East Respiratory syndrome (MERS) first emerged in Saudi Arabia in 2012 and remains a global health concern. The objective of this study was to compare the clinical features and risk factors for adverse outcome in patients with RT-PCR confirmed ...
Musa A Garbati   +8 more
doaj   +1 more source

A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines. [PDF]

open access: yesPLoS ONE, 2013
An emerging respiratory infectious disease with high mortality, Middle East respiratory syndrome (MERS), is caused by a novel coronavirus (MERS-CoV). It was first reported in 2012 in Saudi Arabia and has now spread to eight countries.
Lanying Du   +10 more
doaj   +1 more source

Molecular aspects of MERS-CoV [PDF]

open access: yesFrontiers of Medicine, 2017
Middle East respiratory syndrome coronavirus (MERS-CoV) is a betacoronavirus which can cause acute respiratory distress in humans and is associated with a relatively high mortality rate. Since it was first identified in a patient who died in a Jeddah hospital in 2012, the World Health Organization has been notified of 1735 laboratory-confirmed cases ...
Rabaan, Ali A.   +3 more
openaire   +2 more sources

Bactrian camels shed large quantities of Middle East respiratory syndrome coronavirus (MERS-CoV) after experimental infection

open access: yesEmerging Microbes and Infections, 2019
In 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) emerged. To date, more than 2300 cases have been reported, with an approximate case fatality rate of 35%.
Danielle R. Adney   +6 more
doaj   +1 more source

The medical and biochemical knowledge of health care professionals regarding the management of MERS-CoV: lessons from 2019 pilgrimage season in Al-Madinah, Saudi Arabia: A cross-sectional study

open access: yesSVU - International Journal of Medical Sciences, 2023
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) epidemic was a serious healthcare concern not responding to conventional anti-viral therapies between 2012 and 2017 with high fatality rates.
Mariam Eid Alanzi   +30 more
doaj   +1 more source

Growth and Quantification of MERS‐CoV Infection [PDF]

open access: yesCurrent Protocols in Microbiology, 2015
AbstractMiddle East respiratory syndrome coronavirus (MERS‐CoV) is an emerging highly pathogenic respiratory virus. Although MERS‐CoV only emerged in 2012, we and others have developed assays to grow and quantify infectious MERS‐CoV and RNA products of replication in vitro. MERS‐CoV is able to infect a range of cell types, but replicates to high titers
Coleman, Christopher M.   +1 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy