Results 11 to 20 of about 27,602 (177)

Enhancing immune protection against MERS-CoV: the synergistic effect of proteolytic cleavage sites and the fusion peptide and RBD domain targeting VLP immunization

Frontiers in Immunology, 2023
IntroductionThe Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic infectious virus that has caused significant outbreaks in the Middle East and beyond.
Jeein Oh, Uni Park, Juhyung Kim, Kyeongseok Jeon, Kyeongseok Jeon, Chulwoo Kim, Nam-Hyuk Cho, Nam-Hyuk Cho, Nam-Hyuk Cho, Youn Soo Choi, Youn Soo Choi, Youn Soo Choi   +11 more
doaj   +1 more source

Liposome-Mediated Delivery of MERS Antigen Induces Potent Humoral and Cell-Mediated Immune Response in Mice

Molecules, 2022
The advancements in the field of nanotechnology have provided a great platform for the development of effective antiviral vaccines. Liposome-mediated delivery of antigens has been shown to induce the antigen-specific stimulation of the humoral and cell ...
Masood Alam Khan, Ajamaluddin Malik, Mohammad A. Alzohairy, Abdulmohsen M. Alruwetei, Bader Y. Alhatlani, Osamah Al Rugaie, Arif Khan   +6 more
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Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus

Emerging Microbes and Infections, 2020
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) causes a severe respiratory disease in humans. The MERS-CoV spike (S) glycoprotein mediates viral entry into target cells.
Hannah Kleine-Weber, Simon Schroeder, Nadine Krüger, Alexander Prokscha, Hassan Y. Naim, Marcel A. Müller, Christian Drosten, Stefan Pöhlmann, Markus Hoffmann   +8 more
doaj   +1 more source

A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines. [PDF]

PLoS ONE, 2013
An emerging respiratory infectious disease with high mortality, Middle East respiratory syndrome (MERS), is caused by a novel coronavirus (MERS-CoV). It was first reported in 2012 in Saudi Arabia and has now spread to eight countries.
Lanying Du, Zhihua Kou, Cuiqing Ma, Xinrong Tao, Lili Wang, Guangyu Zhao, Yaoqing Chen, Fei Yu, Chien-Te K Tseng, Yusen Zhou, Shibo Jiang   +10 more
doaj   +1 more source

The medical and biochemical knowledge of health care professionals regarding the management of MERS-CoV: lessons from 2019 pilgrimage season in Al-Madinah, Saudi Arabia: A cross-sectional study

SVU - International Journal of Medical Sciences, 2023
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) epidemic was a serious healthcare concern not responding to conventional anti-viral therapies between 2012 and 2017 with high fatality rates.
Mariam Eid Alanzi, Mona Ali H. Albalawi , Saeed Kabrah, Yasmeen Talal Aljehani , Ahmed M. Okashah, Ayman M Yenbaawi, Sami Saleem Alrehaily , Areej Meshal Aljumaidi , Bandar Alkabli , Mohamed Hamed Almutairi , Riyadh Alghamdi, Manal Ali Alsharif , Zohoor Dahie Aljohani, Rehab Ismail H. Alribyawi , Sultan Ahmed H. Alluqmany , Ahlam Awad Aljohani , Suzan Talal Aljehani , Zain Jaber Alghamdi, Ahmad Mohsen Aljermaawi , Amir Gadhyan Aldebeesi , May Mohamed Almutairi, Khalid Eid Alanzi , Nusaybah Eid Alanzi , Saud Idris Umar , Fahad Majed Almutari, Hamza Bakeet Altorgmi, Osama Abdel-Mageed, Abdel-Raheem Donkol , Mohamed Abdel-Haleem, Hussam H. Baghdadi, Salah Mohamed El Sayed*   +30 more
doaj   +1 more source

Drivers of MERS-CoV transmission: what do we know? [PDF]

, 2016
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is Endemic [PDF]

Emerging Infectious Diseases, 2016
To the Editor: Accumulating evidence indicates that dromedaries (Camelus dromedarius) are a reservoir for zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Although numerous studies have looked at other livestock in the Middle East region, evidence for MERS-CoV infection has only been found in dromedaries (1).
Reusken, Chantal B E M, Schilp, Chrispijn, Raj, V Stalin, De Bruin, Erwin, Kohl, Robert H G, Farag, Elmoubasher A B A, Haagmans, Bart L, Al-Romaihi, Hamad, Le Grange, Francois, Bosch, Berend-Jan, Koopmans, Marion P G   +10 more
openaire   +3 more sources

MERS-CoV Confirmation among 6,873 suspected persons and relevant Epidemiologic and Clinical Features, Saudi Arabia — 2014 to 2019

EClinicalMedicine, 2021
Background: Of the three lethal coronaviruses, in addition to the ongoing pandemic-causing SARS-CoV 2, Middle East Respiratory Syndrome Coronavirus (MERS-CoV) remains in circulation. Information on MERS-CoV has relied on small sample of patients.
Shahul H. Ebrahim, MD, PhD, Andrew D. Maher, MPH, Udhayashankar Kanagasabai, MD, MPH, Sarah H. Alfaraj, MD, Nojom A. Alzahrani, Saleh A. Alqahtani, MD, Abdullah M. Assiri, MD, Ziad A. Memish, MD   +7 more
doaj   +1 more source

MERS-CoV in Arabian camels in Africa and Central Asia [PDF]

, 2017
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causing infections in humans is genetically indistinguishable from the virus found in Arabian camels (dromedaries) in the Middle East. Although no primary human case of MERS was reported outside the
Chan, Samuel M.S., Chevalier, Véronique, Chu, Daniel K.W., Miguel, Eve, Peiris, Malik, Perera, Ranawaka A.P.M., Poon, Leo L.M., Roger, François   +7 more
core   +1 more source

Bactrian camels shed large quantities of Middle East respiratory syndrome coronavirus (MERS-CoV) after experimental infection

Emerging Microbes and Infections, 2019
In 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) emerged. To date, more than 2300 cases have been reported, with an approximate case fatality rate of 35%.
Danielle R. Adney, Michael Letko, Izabela K. Ragan, Dana Scott, Neeltje van Doremalen, Richard A. Bowen, Vincent J. Munster   +6 more
doaj   +1 more source