Results 11 to 20 of about 252,954 (227)

Growth and Quantification of MERS‐CoV Infection [PDF]

open access: yesCurrent Protocols in Microbiology, 2015
AbstractMiddle East respiratory syndrome coronavirus (MERS‐CoV) is an emerging highly pathogenic respiratory virus. Although MERS‐CoV only emerged in 2012, we and others have developed assays to grow and quantify infectious MERS‐CoV and RNA products of replication in vitro. MERS‐CoV is able to infect a range of cell types, but replicates to high titers
Coleman, Christopher M.   +1 more
openaire   +3 more sources

Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus [PDF]

open access: yesmBio, 2014
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first documented in the Kingdom of Saudi Arabia (KSA) in 2012 and, to date, has been identified in 180 cases with 43% mortality.
Matthew Cotten   +19 more
doaj   +2 more sources

Evaluation of a Rapid Immunochromatographic Middle East Respiratory Syndrome Coronavirus Antigen Detection Assay

open access: yesInfectious Microbes & Diseases, 2022
. Middle East respiratory syndrome coronavirus (MERS-CoV) infection in humans has a high mortality of >30%. Dromedaries are the reservoir of MERS-CoV and the main source of human infections.
Susanna Kar-Pui Lau   +7 more
doaj   +1 more source

Enhancing immune protection against MERS-CoV: the synergistic effect of proteolytic cleavage sites and the fusion peptide and RBD domain targeting VLP immunization

open access: yesFrontiers in Immunology, 2023
IntroductionThe Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic infectious virus that has caused significant outbreaks in the Middle East and beyond.
Jeein Oh   +11 more
doaj   +1 more source

Liposome-Mediated Delivery of MERS Antigen Induces Potent Humoral and Cell-Mediated Immune Response in Mice

open access: yesMolecules, 2022
The advancements in the field of nanotechnology have provided a great platform for the development of effective antiviral vaccines. Liposome-mediated delivery of antigens has been shown to induce the antigen-specific stimulation of the humoral and cell ...
Masood Alam Khan   +6 more
doaj   +1 more source

MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is Endemic [PDF]

open access: yesEmerging Infectious Diseases, 2016
To the Editor: Accumulating evidence indicates that dromedaries (Camelus dromedarius) are a reservoir for zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Although numerous studies have looked at other livestock in the Middle East region, evidence for MERS-CoV infection has only been found in dromedaries (1).
Reusken, Chantal B.E.M.   +10 more
openaire   +4 more sources

State of Knowledge and Data Gaps of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Humans [PDF]

open access: yes, 2013
Background: Between September 2012 and 22 October 2013, 144 laboratory-confirmed and 17 probable MERS-CoV cases from nine countries were notified to WHO.
MERS-CoV, Research Group WHO   +3 more
core   +2 more sources

Molecular aspects of MERS-CoV [PDF]

open access: yesFrontiers of Medicine, 2017
Middle East respiratory syndrome coronavirus (MERS-CoV) is a betacoronavirus which can cause acute respiratory distress in humans and is associated with a relatively high mortality rate. Since it was first identified in a patient who died in a Jeddah hospital in 2012, the World Health Organization has been notified of 1735 laboratory-confirmed cases ...
Rabaan, Ali A.   +3 more
openaire   +2 more sources

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus

open access: yesEmerging Microbes and Infections, 2020
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) causes a severe respiratory disease in humans. The MERS-CoV spike (S) glycoprotein mediates viral entry into target cells.
Hannah Kleine-Weber   +8 more
doaj   +1 more source

A Comparative Study of Clinical Presentation and Risk Factors for Adverse Outcome in Patients Hospitalised with Acute Respiratory Disease Due to MERS Coronavirus or Other Causes. [PDF]

open access: yesPLoS ONE, 2016
Middle East Respiratory syndrome (MERS) first emerged in Saudi Arabia in 2012 and remains a global health concern. The objective of this study was to compare the clinical features and risk factors for adverse outcome in patients with RT-PCR confirmed ...
Musa A Garbati   +8 more
doaj   +1 more source

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