Results 131 to 140 of about 338,568 (266)
Bunching Transitions on Vicinal Surfaces and Quantum N-mers
We study vicinal crystal surfaces with the terrace-step-kink model on a discrete lattice. Including both a short-ranged attractive interaction and a long-ranged repulsive interaction arising from elastic forces, we discover a series of phases in which ...
B. Sutherland +16 more
core +1 more source
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng +9 more
wiley +1 more source
Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi +21 more
wiley +1 more source
Time‐Efficient and Informatic‐Skill‐Light Gap‐Filling for Telomere‐to‐Telomere Genome Assembly
The paper introduces a novel auxiliary software toolbox GapSuite, consisting of two tools Gap‐Aid and Gap‐Graph, which guides users to fill gaps in chromosome‐level genome assembly using sequence‐extension‐based and assembly‐graph‐based strategies. The two tools enable users with limited informatics expertise to efficiently complete gap‐filling on ...
Dong Xu +8 more
wiley +1 more source
Aerogel Scaffolds: Breathing Life Into Tissue Repair and Companion Diagnostics
Aerogel scaffolds are emerging as multifunctional biomedical platforms that bridge regenerative engineering and molecular diagnostics. By integrating hierarchical porosity, tunable mechanics, and programmable surface chemistry, aerogels can simultaneously support tissue reconstruction and enable localized biomarker sampling and signal transduction ...
Hanlin Zhang +5 more
wiley +1 more source
Insights into Api m 10‐Isoforms and Splice Variants: More Than One Major IgE‐Binding Epitope
The structural, clinical and preclinical insights into Api m 10 and its immunodominant epitopes gained in this study provide substantial insights for the future development of active and passive VIT as well as further treatment approaches. ABSTRACT Background Honey bee venom (HBV) often triggers severe IgE‐mediated allergies.
Kathrin Elisabeth Paulus‐Tremel +7 more
wiley +1 more source
Are Cancer Patients at Higher Risk of Death with COVID-19? [PDF]
Jacob J. Adashek +3 more
doaj +1 more source
Over-represented sequences located on UTRs are potentially involved in regulatory functions [PDF]
Eukaryotic gene expression must be coordinated for the proper functioning of biological processes. This coordination can be achieved both at the transcriptional and post-transcriptional levels.
Carolina B. Livi +6 more
core
Immunisation with adenovirus (Ad) vectors followed by Modified Vaccinia Virus Ankara—strain Bavarian Nordic (MVA‐BN) vectors expressing HPV16 and HPV18 engineered antigens induced antigen‐specific polyfunctional T cells in mice, rhesus macaques and persistent HPV16/HPV18 infected human females vaccines (n = 5). These data showed the promise of the Ad26‐
Selina Khan +15 more
wiley +1 more source

