Results 121 to 130 of about 3,785 (176)
The Thymic Microenvironment Shapes Age‐Related Qualitative Changes in the TCR Repertoire
Ageing profoundly alters the thymic microenvironment, but its impact on T‐cell receptor (TCR) repertoire selection remains unclear. By sequencing TCRαβ repertoires from young and aged thymus, hydrocortisone‐depleted thymus and RAG1‐deficient thymus transplantation models, we show that the aged thymic microenvironment drives qualitative changes in TCR ...
Jasmine Rowell +8 more
wiley +1 more source
ABSTRACT Using the US Agency for International Development (USAID) PREDICT program as a case study, I argue that mainstream emerging disease science (re)produces Orientalist imaginaries of pandemic risk through narratives about wildlife infections as inherently “backwards” in epidemic time relative to human and domestic animal infections. This temporal
Mollie Holmberg
wiley +1 more source
ABSTRACT Online dissemination of conspiracy theories (CTs) during epidemics poses significant risks to public health. This paper addresses the problem of detecting CTs in social media posts with an emphasis on the resource‐constrained scenarios characterized by the scarcity of labelled datasets and expert annotations, and the lack of computational ...
Ipek Baris Schlicht +4 more
wiley +1 more source
BAFF and APRIL Receptors in B Cell Immunity and Autoimmunity
ABSTRACT BAFF and APRIL are TNF superfamily proteins that bind to BAFFR, TACI and BCMA, members of the TNF receptor superfamily. These proteins have both unique and overlapping roles in B cell development and survival and are major therapeutic targets for antibody‐ and B‐cell‐driven pathologies.
Daisy H. Luff +2 more
wiley +1 more source
ABSTRACT Several species of North American bumble bees spanning the Pacific Coastal and Rocky Mountain regions converge onto distinct mimetic abdominal colour forms for each region by switching abdominal coloration from black to red. Previous genome‐wide association studies (GWAS) of red and black transitions in two mimics (Bombus melanopygus and ...
Tunç Dabak +5 more
wiley +1 more source
openaire +1 more source

