Results 101 to 110 of about 3,785 (176)
Abstract We introduce a pseudoassembly approach to identifying variation in sets of genomic sequences via colored de Bruijn graphs. Our pseudoassembly method is implemented in a program called klue that assembles k-mers into sequences compatible with a variant-aware extension of ...
Delaney K. Sullivan +2 more
openaire +2 more sources
ChemistryEurope, Volume 4, Issue 9, September 2026.A single amino acid substitution combined with peptide macrocyclization enhances the affinity of a β‐hairpin peptide for the oncogenic protein β‐catenin. Crystallographic and molecular dynamics analyses reveal that solution‐state preorganization through β‐hairpin stabilization, rather than direct protein contacts, is responsible for the increased ...
Michael H. N. Meulendijks +11 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 9, September 2026.We present a high‐quality chromosome‐level genome assembly and population genomic analysis of the critically endangered Goliath grouper (Epinephelus itajara) using PacBio HiFi and Illumina sequencing technologies. The 1.12 Gb genome assembly showed high contiguity and identified 22,692 protein‐coding genes, while comparative analyses revealed conserved
Juan Esteban Jácome Castro +6 more
wiley +1 more source
European Journal of Immunology, Volume 56, Issue 9, September 2026.Whether viral lipids can directly interact with pattern recognition receptors to modulate antiviral immune responses remains unclear. We show that Mincle‐dependent recognition of HCMV viral particles induces proinflammatory cytokine production in primary human macrophages.
Vladimir Bokun +6 more
wiley +1 more source
Advanced Genetics, Volume 7, Issue 3, September 2026.Microbiome foundation models are framed as a multiscale route from sequence semantics to community ecology, multimodal alignment and future world models. By learning transferable representations across cohorts, habitats and perturbations, this roadmap highlights how microbiome AI can move beyond association‐driven analysis toward interpretable ...
Haohong Zhang, Zixin Kang, Kang Ning
wiley +1 more source
iNew Medicine, Volume 2, Issue 3, September 2026.ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu +22 more
wiley +1 more source
Predicting the Toxicity of Chemical Compounds via Hyperdimensional Computing
Molecular Informatics, Volume 45, Issue 9, September 2026.Hyperdimensional computing converts text representations of chemical structures (SMILES) into high‐dimensional vectors. New compounds are classified by comparison with learned toxic and nontoxic reference patterns; across 12 Tox21 targets, overlapping four‐character SMILES patterns performed best among tested representations, supporting fast ...
Fabio Cumbo +6 more
wiley +1 more source
Adult Blow Flies Host Diverse Carrion‐Associated Microbiomes
New Zealand Journal of Zoology, Volume 53, Issue 3, September 2026.Blow flies (Diptera: Calliphoridae) perform important yet often overlooked roles in ecosystems as decomposers, pollinators and vectors of disease. Central to these functions are their associations with microbial communities, which are maintained through close contact with diverse microbe‐rich substrates such as carrion, dung and flowers.
Paige Matheson +5 more
wiley +1 more source